Exact Mass: 488.3039

Exact Mass Matches: 488.3039

Found 36 metabolites which its exact mass value is equals to given mass value 488.3039, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

N-Eicosapentaenoyl Tryptophan

2-(icosa-5,8,11,14,17-pentaenamido)-3-(1H-indol-3-yl)propanoic acid

C31H40N2O3 (488.3039)


N-eicosapentaenoyl tryptophan belongs to the class of compounds known as N-acylamides. These are molecules characterized by a fatty acyl group linked to a primary amine by an amide bond. More specifically, it is an Eicosapentaenoic acid amide of Tryptophan. It is believed that there are more than 800 types of N-acylamides in the human body. N-acylamides fall into several categories: amino acid conjugates (e.g., those acyl amides conjugated with amino acids), neurotransmitter conjugates (e.g., those acylamides conjugated with neurotransmitters), ethanolamine conjugates (e.g., those acylamides conjugated to ethanolamine), and taurine conjugates (e.g., those acyamides conjugated to taurine). N-Eicosapentaenoyl Tryptophan is an amino acid conjugate. N-acylamides can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain N-acylamides; 2) medium-chain N-acylamides; 3) long-chain N-acylamides; and 4) very long-chain N-acylamides; 5) hydroxy N-acylamides; 6) branched chain N-acylamides; 7) unsaturated N-acylamides; 8) dicarboxylic N-acylamides and 9) miscellaneous N-acylamides. N-Eicosapentaenoyl Tryptophan is therefore classified as a long chain N-acylamide. N-acyl amides have a variety of signaling functions in physiology, including in cardiovascular activity, metabolic homeostasis, memory, cognition, pain, motor control and others (PMID: 15655504). N-acyl amides have also been shown to play a role in cell migration, inflammation and certain pathological conditions such as diabetes, cancer, neurodegenerative disease, and obesity (PMID: 23144998; PMID: 25136293; PMID: 28854168).N-acyl amides can be synthesized both endogenously and by gut microbiota (PMID: 28854168). N-acylamides can be biosynthesized via different routes, depending on the parent amine group. N-acyl ethanolamines (NAEs) are formed via the hydrolysis of an unusual phospholipid precursor, N-acyl-phosphatidylethanolamine (NAPE), by a specific phospholipase D. N-acyl amino acids are synthesized via a circulating peptidase M20 domain containing 1 (PM20D1), which can catalyze the bidirectional the condensation and hydrolysis of a variety of N-acyl amino acids. The degradation of N-acylamides is largely mediated by an enzyme called fatty acid amide hydrolase (FAAH), which catalyzes the hydrolysis of N-acylamides into fatty acids and the biogenic amines. Many N-acylamides are involved in lipid signaling system through interactions with transient receptor potential channels (TRP). TRP channel proteins interact with N-acyl amides such as N-arachidonoyl ethanolamide (Anandamide), N-arachidonoyl dopamine and others in an opportunistic fashion (PMID: 23178153). This signaling system has been shown to play a role in the physiological processes involved in inflammation (PMID: 25136293). Other N-acyl amides, including N-oleoyl-glutamine, have also been characterized as TRP channel antagonists (PMID: 29967167). N-acylamides have also been shown to have G-protein-coupled receptors (GPCRs) binding activity (PMID: 28854168). The study of N-acylamides is an active area of research and it is likely that many novel N-acylamides will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered for these molecules.

   

Ile Ile Ile Met

(2S)-2-[(2S,3S)-2-[(2S,3S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-3-methylpentanamido]-3-methylpentanamido]-4-(methylsulfanyl)butanoic acid

C23H44N4O5S (488.3032)


   

Ile Ile Leu Met

(2S)-2-[(2S)-2-[(2S,3S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-3-methylpentanamido]-4-methylpentanamido]-4-(methylsulfanyl)butanoic acid

C23H44N4O5S (488.3032)


   

Ile Ile Met Ile

(2S,3S)-2-[(2S)-2-[(2S,3S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-3-methylpentanamido]-4-(methylsulfanyl)butanamido]-3-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Ile Ile Met Leu

(2S)-2-[(2S)-2-[(2S,3S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-3-methylpentanamido]-4-(methylsulfanyl)butanamido]-4-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Ile Leu Ile Met

(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-4-methylpentanamido]-3-methylpentanamido]-4-(methylsulfanyl)butanoic acid

C23H44N4O5S (488.3032)


   

Ile Leu Leu Met

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-4-methylpentanamido]-4-methylpentanamido]-4-(methylsulfanyl)butanoic acid

C23H44N4O5S (488.3032)


   

Ile Leu Met Ile

(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-4-methylpentanamido]-4-(methylsulfanyl)butanamido]-3-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Ile Leu Met Leu

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-4-methylpentanamido]-4-(methylsulfanyl)butanamido]-4-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Ile Met Ile Ile

(2S,3S)-2-[(2S,3S)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-4-(methylsulfanyl)butanamido]-3-methylpentanamido]-3-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Ile Met Ile Leu

(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-4-(methylsulfanyl)butanamido]-3-methylpentanamido]-4-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Ile Met Leu Ile

(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-4-(methylsulfanyl)butanamido]-4-methylpentanamido]-3-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Ile Met Leu Leu

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-4-(methylsulfanyl)butanamido]-4-methylpentanamido]-4-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Leu Ile Ile Met

(2S)-2-[(2S,3S)-2-[(2S,3S)-2-[(2S)-2-amino-4-methylpentanamido]-3-methylpentanamido]-3-methylpentanamido]-4-(methylsulfanyl)butanoic acid

C23H44N4O5S (488.3032)


   

Leu Ile Leu Met

(2S)-2-[(2S)-2-[(2S,3S)-2-[(2S)-2-amino-4-methylpentanamido]-3-methylpentanamido]-4-methylpentanamido]-4-(methylsulfanyl)butanoic acid

C23H44N4O5S (488.3032)


   

Leu Ile Met Ile

(2S,3S)-2-[(2S)-2-[(2S,3S)-2-[(2S)-2-amino-4-methylpentanamido]-3-methylpentanamido]-4-(methylsulfanyl)butanamido]-3-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Leu Ile Met Leu

(2S)-2-[(2S)-2-[(2S,3S)-2-[(2S)-2-amino-4-methylpentanamido]-3-methylpentanamido]-4-(methylsulfanyl)butanamido]-4-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Leu Leu Ile Met

(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanamido]-3-methylpentanamido]-4-(methylsulfanyl)butanoic acid

C23H44N4O5S (488.3032)


   

Leu Leu Leu Met

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanamido]-4-methylpentanamido]-4-(methylsulfanyl)butanoic acid

C23H44N4O5S (488.3032)


   

Leu Leu Met Ile

(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanamido]-4-(methylsulfanyl)butanamido]-3-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Leu Leu Met Leu

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanamido]-4-(methylsulfanyl)butanamido]-4-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Leu Met Ile Ile

(2S,3S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-(methylsulfanyl)butanamido]-3-methylpentanamido]-3-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Leu Met Ile Leu

(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-(methylsulfanyl)butanamido]-3-methylpentanamido]-4-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Leu Met Leu Ile

(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-(methylsulfanyl)butanamido]-4-methylpentanamido]-3-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Leu Met Leu Leu

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-(methylsulfanyl)butanamido]-4-methylpentanamido]-4-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Met Ile Ile Ile

(2S,3S)-2-[(2S,3S)-2-[(2S,3S)-2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]-3-methylpentanamido]-3-methylpentanamido]-3-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Met Ile Ile Leu

(2S)-2-[(2S,3S)-2-[(2S,3S)-2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]-3-methylpentanamido]-3-methylpentanamido]-4-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Met Ile Leu Ile

(2S,3S)-2-[(2S)-2-[(2S,3S)-2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]-3-methylpentanamido]-4-methylpentanamido]-3-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Met Ile Leu Leu

(2S)-2-[(2S)-2-[(2S,3S)-2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]-3-methylpentanamido]-4-methylpentanamido]-4-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Met Leu Ile Ile

(2S,3S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]-4-methylpentanamido]-3-methylpentanamido]-3-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Met Leu Ile Leu

(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]-4-methylpentanamido]-3-methylpentanamido]-4-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Met Leu Leu Ile

(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]-4-methylpentanamido]-4-methylpentanamido]-3-methylpentanoic acid

C23H44N4O5S (488.3032)


   

Met Leu Leu Leu

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]-4-methylpentanamido]-4-methylpentanamido]-4-methylpentanoic acid

C23H44N4O5S (488.3032)


   

tridecylbenzenesulphonic acid, compound with 2,2,2-nitrilotriethanol (1:1)

tridecylbenzenesulphonic acid, compound with 2,2,2-nitrilotriethanol (1:1)

C25H46NO6S (488.3046)


   

N-Eicosapentaenoyl Tryptophan

N-Eicosapentaenoyl Tryptophan

C31H40N2O3 (488.3039)


   

NA-Trp 20:5(5Z,8Z,11Z,14Z,17Z)

NA-Trp 20:5(5Z,8Z,11Z,14Z,17Z)

C31H40N2O3 (488.3039)