Exact Mass: 485.08822019999997
Exact Mass Matches: 485.08822019999997
Found 10 metabolites which its exact mass value is equals to given mass value 485.08822019999997
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Crizotinib (hydrochloride)
Crizotinib hydrochloride (PF-02341066 hydrochloride) is an orally bioavailable, selective, and ATP-competitive dual ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib hydrochloride (PF-02341066 hydrochloride) inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. It is also a ROS proto-oncogene 1 (ROS1) inhibitor. Crizotinib hydrochloride (PF-02341066 hydrochloride) has effective tumor growth inhibition[1][2][3].
CHIR-98014
C20H17Cl2N9O2 (485.08822019999997)
(E)-ethyl 5-(benzyloxy)-6-broMo-2-(3-ethoxy-3-oxoprop-1-en-1-yl)-1-Methyl-1H-indole-3-carboxylate
C24H24BrNO5 (485.08377540000004)
Asciminib hydrochloride
C20H19Cl2F2N5O3 (485.0832948000001)
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor