Exact Mass: 481.09916699999997

Exact Mass Matches: 481.09916699999997

Found 1 metabolites which its exact mass value is equals to given mass value 481.09916699999997, within given mass tolerance error 1.6E-6 dalton. Try search metabolite list with more accurate mass tolerance error 3.2E-7 dalton.

UC2288

UC2288

C20H18ClF6N3O2 (481.09916699999997)


UC2288 is a novel, cell-permeable, and orally active p21 attenuator (relatively selective activity for p21), which is synthesized based Sorafenib (HY-10201). UC2288 decreases p21 mRNA expression independently of p53, and attenuates p21 protein levels with minimal effect on p21 protein stability. UC2288 has no inhibition of VEGFR2 and Raf kinases even at 10 μM[1].