Exact Mass: 467.17663440000007
Exact Mass Matches: 467.17663440000007
Found 2 metabolites which its exact mass value is equals to given mass value 467.17663440000007,
within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error
8.0E-6 dalton.
4-Hydroxytamoxifen sulfate
C26H29NO5S (467.17663440000007)
4-Hydroxytamoxifen sulfate is a metabolite of tamoxifen. Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a mixed agonist/antagonist. Tamoxifen is the usual endocrine therapy for hormone receptor-positive breast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting. (Wikipedia)