Exact Mass: 463.1968
Exact Mass Matches: 463.1968
Found 329 metabolites which its exact mass value is equals to given mass value 463.1968
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
4-Hydroxynonenal glutathione
4-Hydroxynonenal glutathione (4-HNE-GSH) is the conjugated product of 4-hydroxy-2-nonenal with glutathione that is synthesized from a reaction catalyzed by glutathione transferases (GSTs). 4-Hydroxy-2-nonenal (4-HNE) is a major lipid peroxidation end product that is known to be highly toxic and very stable. It has been implicated in the pathogenesis and progression of a multitude of human diseases (e.g. cataractogenesis, diabetes, atherosclerosis, osteoporosis, Alzheimers disease, Parkinsons disease, multiple schlerosis, cancer, etc.) (PMID: 23848536). The primary mechanism of 4-HNE detoxification is via its conjugation to glutathione (PMID: 12892994).
Lys Ser Asp Asp
Asp Ser Lys Asp
Ala Gly Met Trp
Ala Gly Trp Met
Ala Met Gly Trp
Ala Met Trp Gly
Ala Asn Pro Tyr
Ala Asn Tyr Pro
Ala Pro Asn Tyr
Ala Pro Tyr Asn
Ala Ser Thr Trp
Ala Ser Trp Thr
Ala Thr Ser Trp
Ala Thr Trp Ser
Ala Trp Gly Met
Ala Trp Met Gly
Ala Trp Ser Thr
Ala Trp Thr Ser
Ala Tyr Asn Pro
Ala Tyr Pro Asn
Cys Gly Val Trp
Cys Gly Trp Val
Cys Val Gly Trp
Cys Val Trp Gly
Cys Trp Gly Val
Cys Trp Val Gly
Asp Asp Lys Ser
Asp Asp Ser Lys
Asp Lys Asp Ser
Asp Lys Ser Asp
Asp Gln Thr Thr
Asp Arg Ser Ser
Asp Ser Asp Lys
Asp Ser Arg Ser
Asp Ser Ser Arg
Asp Thr Gln Thr
Asp Thr Thr Gln
Glu Asn Thr Thr
Glu Gln Ser Thr
Glu Gln Thr Ser
Glu Ser Gln Thr
Glu Ser Thr Gln
Glu Thr Asn Thr
Glu Thr Gln Ser
Glu Thr Ser Gln
Glu Thr Thr Asn
Phe Asn Pro Ser
Phe Asn Ser Pro
Phe Pro Asn Ser
Phe Pro Ser Asn
Phe Ser Asn Pro
Phe Ser Pro Asn
Gly Ala Met Trp
Gly Ala Trp Met
Gly Cys Val Trp
Gly Cys Trp Val
Gly His His Asn
Gly His Asn His
Gly Met Ala Trp
Gly Met Trp Ala
Gly Asn His His
Gly Pro Gln Tyr
Gly Pro Tyr Gln
Gly Gln Pro Tyr
Gly Gln Tyr Pro
Gly Thr Thr Trp
Gly Thr Trp Thr
Gly Val Cys Trp
Gly Val Trp Cys
Gly Trp Ala Met
Gly Trp Cys Val
Gly Trp Met Ala
Gly Trp Thr Thr
Gly Trp Val Cys
Gly Tyr Pro Gln
Gly Tyr Gln Pro
His Gly His Asn
His Gly Asn His
His His Gly Asn
His His Asn Gly
His Asn Gly His
His Asn His Gly
Lys Asp Asp Ser
Lys Asp Ser Asp
Met Ala Gly Trp
Met Ala Trp Gly
Met Gly Ala Trp
Met Gly Trp Ala
Met Trp Ala Gly
Met Trp Gly Ala
Asn Ala Pro Tyr
Asn Ala Tyr Pro
Asn Glu Thr Thr
Asn Phe Pro Ser
Asn Phe Ser Pro
Asn Gly His His
Asn His Gly His
Asn His His Gly
Asn Pro Ala Tyr
Asn Pro Phe Ser
Asn Pro Ser Phe
Asn Pro Tyr Ala
Asn Ser Phe Pro
Asn Ser Pro Phe
Asn Thr Glu Thr
Asn Thr Thr Glu
Asn Tyr Ala Pro
Asn Tyr Pro Ala
Pro Ala Asn Tyr
Pro Ala Tyr Asn
Pro Phe Asn Ser
Pro Phe Ser Asn
Pro Gly Gln Tyr
Pro Gly Tyr Gln
Pro Asn Ala Tyr
Pro Asn Phe Ser
Pro Asn Ser Phe
Pro Asn Tyr Ala
Pro Gln Gly Tyr
Pro Gln Tyr Gly
Pro Ser Phe Asn
Pro Ser Asn Phe
Pro Tyr Ala Asn
Pro Tyr Gly Gln
Pro Tyr Asn Ala
Pro Tyr Gln Gly
Gln Asp Thr Thr
Gln Glu Ser Thr
Gln Glu Thr Ser
Gln Gly Pro Tyr
Gln Gly Tyr Pro
Gln Pro Gly Tyr
Gln Pro Tyr Gly
Gln Ser Glu Thr
Gln Ser Thr Glu
Gln Thr Asp Thr
Gln Thr Glu Ser
Gln Thr Ser Glu
Gln Thr Thr Asp
Gln Tyr Gly Pro
Gln Tyr Pro Gly
Arg Asp Ser Ser
Arg Ser Asp Ser
Arg Ser Ser Asp
Ser Ala Thr Trp
Ser Ala Trp Thr
Ser Asp Asp Lys
Ser Asp Lys Asp
Ser Asp Arg Ser
Ser Asp Ser Arg
Ser Glu Gln Thr
Ser Glu Thr Gln
Ser Phe Asn Pro
Ser Phe Pro Asn
Ser Lys Asp Asp
Ser Asn Phe Pro
Ser Asn Pro Phe
Ser Pro Phe Asn
Ser Pro Asn Phe
Ser Gln Glu Thr
Ser Gln Thr Glu
Ser Arg Asp Ser
Ser Arg Ser Asp
Ser Ser Asp Arg
Ser Ser Arg Asp
Ser Thr Ala Trp
Ser Thr Glu Gln
Ser Thr Gln Glu
Ser Thr Trp Ala
Ser Trp Ala Thr
Ser Trp Thr Ala
Thr Ala Ser Trp
Thr Ala Trp Ser
Thr Asp Gln Thr
Thr Asp Thr Gln
Thr Glu Asn Thr
Thr Glu Gln Ser
Thr Glu Ser Gln
Thr Glu Thr Asn
Thr Gly Thr Trp
Thr Gly Trp Thr
Thr Asn Glu Thr
Thr Asn Thr Glu
Thr Gln Asp Thr
Thr Gln Glu Ser
Thr Gln Ser Glu
Thr Gln Thr Asp
Thr Ser Ala Trp
Thr Ser Glu Gln
Thr Ser Gln Glu
Thr Ser Trp Ala
Thr Thr Asp Gln
Thr Thr Glu Asn
Thr Thr Gly Trp
Thr Thr Asn Glu
Thr Thr Gln Asp
Thr Thr Trp Gly
Thr Trp Ala Ser
Thr Trp Gly Thr
Thr Trp Ser Ala
Thr Trp Thr Gly
Val Cys Gly Trp
Val Cys Trp Gly
Val Gly Cys Trp
Val Gly Trp Cys
Val Trp Cys Gly
Val Trp Gly Cys
Trp Ala Gly Met
Trp Ala Met Gly
Trp Ala Ser Thr
Trp Ala Thr Ser
Trp Cys Gly Val
Trp Cys Val Gly
Trp Gly Ala Met
Trp Gly Cys Val
Trp Gly Met Ala
Trp Gly Thr Thr
Trp Gly Val Cys
Trp Met Ala Gly
Trp Met Gly Ala
Trp Ser Ala Thr
Trp Ser Thr Ala
Trp Thr Ala Ser
Trp Thr Gly Thr
Trp Thr Ser Ala
Trp Thr Thr Gly
Trp Val Cys Gly
Trp Val Gly Cys
Tyr Ala Asn Pro
Tyr Ala Pro Asn
Tyr Gly Pro Gln
Tyr Gly Gln Pro
Tyr Asn Ala Pro
Tyr Asn Pro Ala
Tyr Pro Ala Asn
Tyr Pro Gly Gln
Tyr Pro Asn Ala
Tyr Pro Gln Gly
Tyr Gln Gly Pro
Tyr Gln Pro Gly
OPC 31260 HCl
C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist > C2180 - Vasopressin Antagonist D045283 - Natriuretic Agents > D065092 - Antidiuretic Hormone Receptor Antagonists D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents
1-(2-Fluorobenzyl)-3-butyl-8-(N-acetyl-4-aminobenzyl)-xanthine
6-{4-[(1-{[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]carbonyl}azetidin-3-yl)oxy]benzyl}-2-oxa-6-azoniaspiro[3.3]heptane
(2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-(4-hydroxy-1-oxononan-3-yl)sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
4-methyl-N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamide
5-(dimethylsulfamoyl)-N-(diphenylmethyl)-2-(1-pyrrolidinyl)benzamide
5-Methyl-4-[(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)-[1-(1-naphthalenylmethyl)-3-indolyl]methyl]-1,2-dihydropyrazol-3-one
1-[5-(Diethylsulfamoyl)-2-(4-methyl-1-piperazinyl)phenyl]-3-(2-fluorophenyl)urea
2-[(5,5-dimethyl-6H-[1,2,4]triazolo[3,4-a]isoquinolin-3-yl)thio]-1-[4-(2-methoxyphenyl)-1-piperazinyl]ethanone
3,17beta-dihydroxyestra-1,3,5(10)-trien-2-yl beta-D-glucopyranosiduronate
16alpha,17alpha-dihydroxyestra-1(10),2,4-trien-3-yl beta-D-glucopyranosiduronate
Glycine, L-gamma-glutamyl-S-[2-hydroxy-1-(2-oxoethyl)heptyl]-L-cysteinyl-
3,16alpha-dihydroxyestra-1(10),2,4-trien-17alpha-yl beta-D-glucopyranosiduronate
16beta,17beta-dihydroxyestra-1(10),2,4-trien-3-yl beta-D-glucopyranosiduronate
3,17beta-dihydroxyestra-1(10),2,4-trien-4-yl beta-D-glucopyranosiduronate
estriol 16-O-(beta-D-glucuronide)(1-)
A steroid glucuronide anion that is the conjugate base of estriol 16-O-(beta-D-glucuronide) arising from deprotonation of the carboxylic acid function; major species at pH 7.3.
3,17alpha-dihydroxyestra-1(10),2,4-trien-16alpha-yl beta-D-glucopyranosiduronate
3,17beta-dihydroxyestra-1(10),2,4-trien-16beta-yl beta-D-glucopyranosiduronate
2,17beta-dihydroxyestra-1,3,5(10)-trien-3-yl beta-D-glucopyranosiduronate
4,17beta-dihydroxyestra-1(10),2,4-trien-3-yl beta-D-glucopyranosiduronate
2-[2-[2-[(4-Tert-butyl-2,6-dimethylphenyl)thio]ethyl]-1-pyridin-1-iumyl]-1-(4-nitrophenyl)ethanone
N4-(2-amino-5-thiophen-2-ylphenyl)-N1-[2-(4-methyl-1-piperazinyl)ethyl]benzene-1,4-dicarboxamide
1-(4-chlorophenyl)-3-[(2S,3R,6S)-6-[2-[4-(1-hydroxycyclopentyl)-1-triazolyl]ethyl]-2-(hydroxymethyl)-3-oxanyl]urea
1-(4-chlorophenyl)-3-[(2R,3R,6R)-6-[2-[4-(1-hydroxycyclopentyl)-1-triazolyl]ethyl]-2-(hydroxymethyl)-3-oxanyl]urea
1-(4-chlorophenyl)-3-[(2S,3S,6S)-6-[2-[4-(1-hydroxycyclopentyl)-1-triazolyl]ethyl]-2-(hydroxymethyl)-3-oxanyl]urea
1-(4-chlorophenyl)-3-[(2R,3S,6R)-6-[2-[4-(1-hydroxycyclopentyl)-1-triazolyl]ethyl]-2-(hydroxymethyl)-3-oxanyl]urea
1-(4-chlorophenyl)-3-[(2S,3S,6R)-6-[2-[4-(1-hydroxycyclopentyl)-1-triazolyl]ethyl]-2-(hydroxymethyl)-3-oxanyl]urea
1-(4-chlorophenyl)-3-[(2S,3R,6R)-6-[2-[4-(1-hydroxycyclopentyl)-1-triazolyl]ethyl]-2-(hydroxymethyl)-3-oxanyl]urea
1-(4-chlorophenyl)-3-[(2R,3S,6S)-6-[2-[4-(1-hydroxycyclopentyl)-1-triazolyl]ethyl]-2-(hydroxymethyl)-3-oxanyl]urea
1-(4-chlorophenyl)-3-[(2R,3R,6S)-6-[2-[4-(1-hydroxycyclopentyl)-1-triazolyl]ethyl]-2-(hydroxymethyl)-3-oxanyl]urea
estra-1,3,5(10)-triene-3,16alpha,17beta-triol 17-D-glucuronide
SM1-71
SM1-71 (compound 5) is a potent TAK1 inhibitor, with a Ki of 160 nM, it also can covalently inhibit MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2. SM1-71 can inhibit proliferation of multiple cancer cell lines[1][2][3].
Takeda103A
Takeda103A is a potent inhibitor of GRK2. G protein-coupled receptors (GPCRs) are central to many physiological processes. Takeda103A has the potential for the research of heart failure[1].