Exact Mass: 460.2573

Exact Mass Matches: 460.2573

Found 1 metabolites which its exact mass value is equals to given mass value 460.2573, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

Entereg

Alvimopan

C25H36N2O6 (460.2573)


C78272 - Agent Affecting Nervous System > C681 - Opiate Antagonist D005765 - Gastrointestinal Agents Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan dihydrate has selectivity for μ-opioid receptor (Ki=0.47 nM) over κ- and δ-opioid receptors (Kis=100, 12 nM, respectively). Alvimopan dihydrate can be used for the research of postoperative ileus[1][2][3].