Exact Mass: 460.2573

Exact Mass Matches: 460.2573

Found 1 metabolites which its exact mass value is equals to given mass value 460.2573, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

Entereg

Alvimopan

C25H36N2O6 (460.2573)


C78272 - Agent Affecting Nervous System > C681 - Opiate Antagonist D005765 - Gastrointestinal Agents Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC50 of 1.7 nM. Alvimopan dihydrate has selectivity for μ-opioid receptor (Ki=0.47 nM) over κ- and δ-opioid receptors (Kis=100, 12 nM, respectively). Alvimopan dihydrate can be used for the research of postoperative ileus[1][2][3].