Exact Mass: 456.04983999999996

Exact Mass Matches: 456.04983999999996

Found 4 metabolites which its exact mass value is equals to given mass value 456.04983999999996, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

CAY10561

N-[1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]-4-[4-(3-chlorophenyl)-1H-pyrazol-3-yl]-1H-pyrrole-2-carboxamide

C22H15Cl2FN4O2 (456.05560419999995)


   
   

UNC9994 (hydrochloride)

UNC9994 (hydrochloride)

C21H23Cl3N2OS (456.0596598)


UNC9994 hydrochloride is a functionally selective, β-arrestin–biased dopamine D2 receptor (D2R) agonist that selectively activates β-arrestin recruitment and signaling. UNC9994 hydrochloride shows a binding affinity with a Ki of 79 nM for D2R. UNC9994 hydrochloride is also an antagonist of Gi-regulated cAMP production and partial agonist for D2R/β-arrestin-2 interactions. UNC9994 hydrochloride shows antipsychotic-like activity[1].