Exact Mass: 455.166739

Exact Mass Matches: 455.166739

Found 102 metabolites which its exact mass value is equals to given mass value 455.166739, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-methyl-2-oxo-3-phenylmethanesulfonylamino-2H-pyridin-1-yl)-acetamide

N-[(6-Imino-2-methyl-1,6-dihydropyridin-3-yl)methyl]-2-[6-methyl-2-oxo-3-(phenylmethanesulphonamido)-1,2-dihydropyridin-1-yl]ethanimidic acid

C22H25N5O4S (455.16271700000004)


   

N-Pyridazin-3-yl-4-[[3-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]methylidene]piperidine-1-carboxamide

N-(pyridazin-3-yl)-4-[(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methylidene]piperidine-1-carboxamide

C23H20F3N5O2 (455.1569016)


Redafamdastat (PF-04457845) is a highly efficacious and selective FAAH inhibitor with IC50 values is 7.2±0.63 nM and 7.4±0.62 nM for hFAAH and rFAAH, respectively.

   
   
   
   

Ala Asn His Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Ala Asp His Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-carboxypropanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanoic acid

C17H25N7O8 (455.176453)


   

Ala Asp Asn His

(3S)-3-[(2S)-2-aminopropanamido]-3-{[(1S)-2-carbamoyl-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Ala His Asp Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]-3-carbamoylpropanoic acid

C17H25N7O8 (455.176453)


   

Ala His Asn Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Ala Asn Asp His

(3S)-3-[(2S)-2-[(2S)-2-aminopropanamido]-3-carbamoylpropanamido]-3-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp Ala His Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]propanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanoic acid

C17H25N7O8 (455.176453)


   

Asp Ala Asn His

(3S)-3-amino-3-{[(1S)-1-{[(1S)-2-carbamoyl-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp Gly His Gln

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-carboxypropanamido]acetamido}-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanoic acid

C17H25N7O8 (455.176453)


   

Asp Gly Gln His

(3S)-3-amino-3-[({[(1S)-3-carbamoyl-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propyl]carbamoyl}methyl)carbamoyl]propanoic acid

C17H25N7O8 (455.176453)


   

Asp His Ala Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-3-(1H-imidazol-4-yl)propanamido]propanamido]-3-carbamoylpropanoic acid

C17H25N7O8 (455.176453)


   

Asp His Gly Gln

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-3-(1H-imidazol-4-yl)propanamido]acetamido}-4-carbamoylbutanoic acid

C17H25N7O8 (455.176453)


   

Asp His Asn Ala

(3S)-3-amino-3-{[(1S)-1-{[(1S)-2-carbamoyl-1-{[(1S)-1-carboxyethyl]carbamoyl}ethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp His Gln Gly

(3S)-3-amino-3-{[(1S)-1-{[(1S)-3-carbamoyl-1-[(carboxymethyl)carbamoyl]propyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp Asn Ala His

(3S)-3-amino-3-{[(1S)-2-carbamoyl-1-{[(1S)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp Asn His Ala

(3S)-3-amino-3-{[(1S)-2-carbamoyl-1-{[(1S)-1-{[(1S)-1-carboxyethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp Gln Gly His

(3S)-3-amino-3-{[(1S)-3-carbamoyl-1-[({[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}methyl)carbamoyl]propyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asp Gln His Gly

(3S)-3-amino-3-{[(1S)-3-carbamoyl-1-{[(1S)-1-[(carboxymethyl)carbamoyl]-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Glu Gly His Asn

(4S)-4-amino-4-[({[(1S)-1-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}methyl)carbamoyl]butanoic acid

C17H25N7O8 (455.176453)


   

Glu Gly Asn His

(4S)-4-amino-4-[({[(1S)-2-carbamoyl-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}methyl)carbamoyl]butanoic acid

C17H25N7O8 (455.176453)


   

Glu His Gly Asn

(4S)-4-amino-4-{[(1S)-1-[({[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}methyl)carbamoyl]-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Glu His Asn Gly

(4S)-4-amino-4-{[(1S)-1-{[(1S)-2-carbamoyl-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Glu Asn Gly His

(4S)-4-amino-4-{[(1S)-2-carbamoyl-1-[({[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}methyl)carbamoyl]ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Glu Asn His Gly

(4S)-4-amino-4-{[(1S)-2-carbamoyl-1-{[(1S)-1-[(carboxymethyl)carbamoyl]-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Gly Asp His Gln

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-carboxypropanamido]-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanoic acid

C17H25N7O8 (455.176453)


   

Gly Asp Gln His

(3S)-3-(2-aminoacetamido)-3-{[(1S)-3-carbamoyl-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Gly Glu His Asn

(4S)-4-(2-aminoacetamido)-4-{[(1S)-1-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Gly Glu Asn His

(4S)-4-(2-aminoacetamido)-4-{[(1S)-2-carbamoyl-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Gly His Asp Gln

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]-4-carbamoylbutanoic acid

C17H25N7O8 (455.176453)


   

Gly His Glu Asn

(4S)-4-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]-4-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Gly His Asn Glu

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]pentanedioic acid

C17H25N7O8 (455.176453)


   

Gly His Gln Asp

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Gly Asn Glu His

(4S)-4-[(2S)-2-(2-aminoacetamido)-3-carbamoylpropanamido]-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Gly Asn His Glu

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]pentanedioic acid

C17H25N7O8 (455.176453)


   

Gly Gln Asp His

(3S)-3-[(2S)-2-(2-aminoacetamido)-4-carbamoylbutanamido]-3-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Gly Gln His Asp

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-4-carbamoylbutanamido]-3-(1H-imidazol-4-yl)propanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

His Ala Asp Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]propanamido]-3-carboxypropanamido]-3-carbamoylpropanoic acid

C17H25N7O8 (455.176453)


   

His Ala Asn Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]propanamido]-3-carbamoylpropanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

His Asp Ala Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]propanamido]-3-carbamoylpropanoic acid

C17H25N7O8 (455.176453)


   

His Asp Gly Gln

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]acetamido}-4-carbamoylbutanoic acid

C17H25N7O8 (455.176453)


   

His Asp Asn Ala

(3S)-3-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-{[(1S)-2-carbamoyl-1-{[(1S)-1-carboxyethyl]carbamoyl}ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

His Asp Gln Gly

(3S)-3-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-{[(1S)-3-carbamoyl-1-[(carboxymethyl)carbamoyl]propyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

His Glu Gly Asn

(4S)-4-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-[({[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}methyl)carbamoyl]butanoic acid

C17H25N7O8 (455.176453)


   

His Glu Asn Gly

(4S)-4-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-{[(1S)-2-carbamoyl-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

His Gly Asp Gln

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}-3-carboxypropanamido]-4-carbamoylbutanoic acid

C17H25N7O8 (455.176453)


   

His Gly Glu Asn

(4S)-4-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}-4-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

His Gly Asn Glu

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}-3-carbamoylpropanamido]pentanedioic acid

C17H25N7O8 (455.176453)


   

His Gly Gln Asp

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}-4-carbamoylbutanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

His Asn Ala Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]propanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

His Asn Asp Ala

(3S)-3-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]-3-{[(1S)-1-carboxyethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

His Asn Glu Gly

(4S)-4-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]-4-[(carboxymethyl)carbamoyl]butanoic acid

C17H25N7O8 (455.176453)


   

His Asn Gly Glu

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]acetamido}pentanedioic acid

C17H25N7O8 (455.176453)


   

His Gln Asp Gly

(3S)-3-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanamido]-3-[(carboxymethyl)carbamoyl]propanoic acid

C17H25N7O8 (455.176453)


   

His Gln Gly Asp

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-4-carbamoylbutanamido]acetamido}butanedioic acid

C17H25N7O8 (455.176453)


   

Asn Ala Asp His

(3S)-3-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]propanamido]-3-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asn Ala His Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]propanamido]-3-(1H-imidazol-4-yl)propanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Asn Asp Ala His

(3S)-3-[(2S)-2-amino-3-carbamoylpropanamido]-3-{[(1S)-1-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asn Asp His Ala

(3S)-3-[(2S)-2-amino-3-carbamoylpropanamido]-3-{[(1S)-1-{[(1S)-1-carboxyethyl]carbamoyl}-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asn Glu Gly His

(4S)-4-[(2S)-2-amino-3-carbamoylpropanamido]-4-[({[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}methyl)carbamoyl]butanoic acid

C17H25N7O8 (455.176453)


   

Asn Glu His Gly

(4S)-4-[(2S)-2-amino-3-carbamoylpropanamido]-4-{[(1S)-1-[(carboxymethyl)carbamoyl]-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Asn Gly Glu His

(4S)-4-{2-[(2S)-2-amino-3-carbamoylpropanamido]acetamido}-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}butanoic acid

C17H25N7O8 (455.176453)


   

Asn Gly His Glu

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-carbamoylpropanamido]acetamido}-3-(1H-imidazol-4-yl)propanamido]pentanedioic acid

C17H25N7O8 (455.176453)


   

Asn His Ala Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]propanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Asn His Asp Ala

(3S)-3-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-3-{[(1S)-1-carboxyethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Asn His Glu Gly

(4S)-4-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-4-[(carboxymethyl)carbamoyl]butanoic acid

C17H25N7O8 (455.176453)


   

Asn His Gly Glu

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]acetamido}pentanedioic acid

C17H25N7O8 (455.176453)


   

Gln Asp Gly His

(3S)-3-[(2S)-2-amino-4-carbamoylbutanamido]-3-[({[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}methyl)carbamoyl]propanoic acid

C17H25N7O8 (455.176453)


   

Gln Asp His Gly

(3S)-3-[(2S)-2-amino-4-carbamoylbutanamido]-3-{[(1S)-1-[(carboxymethyl)carbamoyl]-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Gln Gly Asp His

(3S)-3-{2-[(2S)-2-amino-4-carbamoylbutanamido]acetamido}-3-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]carbamoyl}propanoic acid

C17H25N7O8 (455.176453)


   

Gln Gly His Asp

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-4-carbamoylbutanamido]acetamido}-3-(1H-imidazol-4-yl)propanamido]butanedioic acid

C17H25N7O8 (455.176453)


   

Gln His Asp Gly

(3S)-3-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-(1H-imidazol-4-yl)propanamido]-3-[(carboxymethyl)carbamoyl]propanoic acid

C17H25N7O8 (455.176453)


   

Gln His Gly Asp

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-(1H-imidazol-4-yl)propanamido]acetamido}butanedioic acid

C17H25N7O8 (455.176453)


   

16-carboxy-Delta(13)-17,18,19,20-tetranor-N-acetyl-leukotriene E4

(5Z,7E,9E,11R,12S)-11-(N-acetyl-L-cystein-S-yl)-12-hydroxyhexadeca-3,5,7,9-tetraenedioic acid;(5Z,7E,9E,11R,12S)-11-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-12-hydroxyhexadeca-3,5,7,9-tetraenedioic acid

C21H29NO8S (455.16137940000004)


   

Lisdexamfetamine dimesylate

(2S)-2,6-diamino-N-[(2S)-1-phenylpropan-2-yl]hexanamide,methanesulfonic acid

C17H33N3O7S2 (455.1759828)


D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant C78272 - Agent Affecting Nervous System > C29728 - Anorexiant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators

   

1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]-1-propanone

1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]-1-propanone

C29H26ClNO2 (455.16519660000006)


   

13H-spiro[benzo[c]indeno[2,1-a]carbazole-14,9-fluorene]

13H-spiro[benzo[c]indeno[2,1-a]carbazole-14,9-fluorene]

C35H21N (455.16739060000003)


   

Moxifloxacin hydrochloride monohydrate

Moxifloxacin hydrochloride monohydrate

C21H27ClFN3O5 (455.16231740000006)


D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones D004791 - Enzyme Inhibitors

   

Allyl-{6-[3-(4-bromo-phenyl)-1-methyl-1H-indazol-6-YL]oxy}hexyl)-N-methylamine

Allyl-{6-[3-(4-bromo-phenyl)-1-methyl-1H-indazol-6-YL]oxy}hexyl)-N-methylamine

C24H30BrN3O (455.157211)


   

3-(2-Chlorophenyl)-1-(2-{[(1S)-2-hydroxy-1,2-dimethylpropyl]amino}pyrimidin-4-YL)-1-(4-methoxyphenyl)urea

3-(2-Chlorophenyl)-1-(2-{[(1S)-2-hydroxy-1,2-dimethylpropyl]amino}pyrimidin-4-YL)-1-(4-methoxyphenyl)urea

C23H26ClN5O3 (455.17240760000004)


   

4-(2-amino-3-cyano-5-oxo-5,6,7,8-tetrahydro-4H-chromen-4-yl)-2,6-dimethoxyphenyl morpholine-4-carboxylate

4-(2-amino-3-cyano-5-oxo-5,6,7,8-tetrahydro-4H-chromen-4-yl)-2,6-dimethoxyphenyl morpholine-4-carboxylate

C23H25N3O7 (455.169242)


   
   
   

AD57

AD57

C22H20F3N7O (455.16813460000003)


AD57 is an orally active multikinase inhibitor, inhibits RET, BRAF, S6K and Src, with greatly reduces mTOR activity[1].

   

GNE-9815

GNE-9815

C26H22FN5O2 (455.1757444)


GNE-9815 (compound 7) is a highly selective, pan-RAF inhibitor with good oral bioavailability. GNE-9815 exhibits Ki values of 0.062 and 0.19 nM for CRAF and BRAF, respectively. GNE-9815 combines with MEK inhibitor Cobimetinib (HY-13064) shows synergistic modulation of MAPK pathway. GNE-9815 can be used in studies of KRAS mutant cancers[1].

   

(1s,6r,10r,12r,19s,20r,21s)-21-(dimethylamino)-16,20-dihydroxy-12,19-dimethyl-7,11,23-trioxahexacyclo[17.3.1.0²,¹⁸.0³,¹⁵.0⁵,¹³.0⁶,¹⁰]tricosa-2,5(13),15,17-tetraene-4,8,14-trione

(1s,6r,10r,12r,19s,20r,21s)-21-(dimethylamino)-16,20-dihydroxy-12,19-dimethyl-7,11,23-trioxahexacyclo[17.3.1.0²,¹⁸.0³,¹⁵.0⁵,¹³.0⁶,¹⁰]tricosa-2,5(13),15,17-tetraene-4,8,14-trione

C24H25NO8 (455.158009)


   

[(2r,3r,4r,5s,6r)-2-{[(2s,3r,4r,5r,6s)-4,5-dihydroxy-2-{[(2s)-1-hydroxy-3-oxopropan-2-yl]oxy}-6-methyloxan-3-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]amino acetate

[(2r,3r,4r,5s,6r)-2-{[(2s,3r,4r,5r,6s)-4,5-dihydroxy-2-{[(2s)-1-hydroxy-3-oxopropan-2-yl]oxy}-6-methyloxan-3-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]amino acetate

C17H29NO13 (455.16388240000003)


   

[2-({4,5-dihydroxy-2-[(1-hydroxy-3-oxopropan-2-yl)oxy]-6-methyloxan-3-yl}oxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]amino acetate

[2-({4,5-dihydroxy-2-[(1-hydroxy-3-oxopropan-2-yl)oxy]-6-methyloxan-3-yl}oxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]amino acetate

C17H29NO13 (455.16388240000003)


   

(2e,4e)-n-[(3s)-7,9-dichloro-2-hydroxy-8-oxo-1-oxaspiro[4.5]deca-6,9-dien-3-yl]-4,6-dimethyldodeca-2,4-dienimidic acid

(2e,4e)-n-[(3s)-7,9-dichloro-2-hydroxy-8-oxo-1-oxaspiro[4.5]deca-6,9-dien-3-yl]-4,6-dimethyldodeca-2,4-dienimidic acid

C23H31Cl2NO4 (455.1630026)


   

3-[({10-amino-10-benzyl-7,9,10a-trihydroxy-3-oxo-1h,2h,5h-pyrrolo[1,2-b]isoquinolin-5-yl}(hydroxy)methylidene)amino]propanoic acid

3-[({10-amino-10-benzyl-7,9,10a-trihydroxy-3-oxo-1h,2h,5h-pyrrolo[1,2-b]isoquinolin-5-yl}(hydroxy)methylidene)amino]propanoic acid

C23H25N3O7 (455.169242)


   

(1's,14'r)-1'-{[(4s)-3-hydroxy-6-oxo-1h,4h-pyrazino[2,1-b]quinazolin-4-yl]methyl}-13'-oxa-8',11'-diazaspiro[cyclopropane-1,10'-tetracyclo[6.5.1.0²,⁷.0¹¹,¹⁴]tetradecane]-2',4',6'-trien-9'-one

(1's,14'r)-1'-{[(4s)-3-hydroxy-6-oxo-1h,4h-pyrazino[2,1-b]quinazolin-4-yl]methyl}-13'-oxa-8',11'-diazaspiro[cyclopropane-1,10'-tetracyclo[6.5.1.0²,⁷.0¹¹,¹⁴]tetradecane]-2',4',6'-trien-9'-one

C25H21N5O4 (455.15934660000005)


   

21-(dimethylamino)-16,20-dihydroxy-12,19-dimethyl-7,11,23-trioxahexacyclo[17.3.1.0²,¹⁸.0³,¹⁵.0⁵,¹³.0⁶,¹⁰]tricosa-2,5(13),15,17-tetraene-4,8,14-trione

21-(dimethylamino)-16,20-dihydroxy-12,19-dimethyl-7,11,23-trioxahexacyclo[17.3.1.0²,¹⁸.0³,¹⁵.0⁵,¹³.0⁶,¹⁰]tricosa-2,5(13),15,17-tetraene-4,8,14-trione

C24H25NO8 (455.158009)


   

(2e,4e,6r)-n-[(2s,3s)-7,9-dichloro-2-hydroxy-8-oxo-1-oxaspiro[4.5]deca-6,9-dien-3-yl]-4,6-dimethyldodeca-2,4-dienimidic acid

(2e,4e,6r)-n-[(2s,3s)-7,9-dichloro-2-hydroxy-8-oxo-1-oxaspiro[4.5]deca-6,9-dien-3-yl]-4,6-dimethyldodeca-2,4-dienimidic acid

C23H31Cl2NO4 (455.1630026)


   

(2s)-3-acetyl-2-aminopentanedioic acid; bis(oxindole)

(2s)-3-acetyl-2-aminopentanedioic acid; bis(oxindole)

C23H25N3O7 (455.169242)


   

(2e,4e)-n-{7,9-dichloro-2-hydroxy-8-oxo-1-oxaspiro[4.5]deca-6,9-dien-3-yl}-4,6-dimethyldodeca-2,4-dienimidic acid

(2e,4e)-n-{7,9-dichloro-2-hydroxy-8-oxo-1-oxaspiro[4.5]deca-6,9-dien-3-yl}-4,6-dimethyldodeca-2,4-dienimidic acid

C23H31Cl2NO4 (455.1630026)


   

(1r,6r,10r,12r,19r,20s,21r)-21-(dimethylamino)-16,20-dihydroxy-12,19-dimethyl-7,11,23-trioxahexacyclo[17.3.1.0²,¹⁸.0³,¹⁵.0⁵,¹³.0⁶,¹⁰]tricosa-2,5(13),15,17-tetraene-4,8,14-trione

(1r,6r,10r,12r,19r,20s,21r)-21-(dimethylamino)-16,20-dihydroxy-12,19-dimethyl-7,11,23-trioxahexacyclo[17.3.1.0²,¹⁸.0³,¹⁵.0⁵,¹³.0⁶,¹⁰]tricosa-2,5(13),15,17-tetraene-4,8,14-trione

C24H25NO8 (455.158009)


   

1'-({3-hydroxy-6-oxo-1h,4h-pyrazino[2,1-b]quinazolin-4-yl}methyl)-13'-oxa-8',11'-diazaspiro[cyclopropane-1,10'-tetracyclo[6.5.1.0²,⁷.0¹¹,¹⁴]tetradecane]-2',4',6'-trien-9'-one

1'-({3-hydroxy-6-oxo-1h,4h-pyrazino[2,1-b]quinazolin-4-yl}methyl)-13'-oxa-8',11'-diazaspiro[cyclopropane-1,10'-tetracyclo[6.5.1.0²,⁷.0¹¹,¹⁴]tetradecane]-2',4',6'-trien-9'-one

C25H21N5O4 (455.15934660000005)