Exact Mass: 453.0252

Exact Mass Matches: 453.0252

Found 3 metabolites which its exact mass value is equals to given mass value 453.0252, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

1-Benzyl-3-Methylimidazolium Bis((Trifluoromethyl)Sulfonyl)Imide

1-Benzyl-3-Methylimidazolium Bis((Trifluoromethyl)Sulfonyl)Imide

C13H13F6N3O4S2 (453.0252)


   

4-Bromo-3-(Carboxymethoxy)-5-[3-(Cyclohexylamino)phenyl]thiophene-2-Carboxylic Acid

4-Bromo-3-(Carboxymethoxy)-5-[3-(Cyclohexylamino)phenyl]thiophene-2-Carboxylic Acid

C19H20BrNO5S (453.0245)


   

NDI-091143

NDI-091143

C20H14ClF2NO5S (453.0249)


NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), a Ki of 7.0 nM and a Kd of 2.2 nM. NDI-091143 inhibits ACLY catalysis allosterically, by stabilizing large conformational changes in the citrate domain that indirectly block the binding and recognition of citrate[1].