Exact Mass: 451.93362160000004

Exact Mass Matches: 451.93362160000004

Found 3 metabolites which its exact mass value is equals to given mass value 451.93362160000004, within given mass tolerance error 8.0E-6 dalton. Try search metabolite list with more accurate mass tolerance error 1.6E-6 dalton.

Fipronil sulfone

5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-trifluoromethanesulfonyl-1H-pyrazole-3-carbonitrile

C12H4Cl2F6N4O2S (451.93362160000004)


D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018756 - GABA Antagonists D010575 - Pesticides > D007306 - Insecticides D016573 - Agrochemicals Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits GABA receptor with IC50 of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site).

   

Fipronil sulfone

FIPRONIL-SULFONE

C12H4Cl2F6N4O2S (451.93362160000004)


D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018756 - GABA Antagonists D010575 - Pesticides > D007306 - Insecticides D016573 - Agrochemicals CONFIDENCE standard compound; INTERNAL_ID 2421 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 8846 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2667 Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits GABA receptor with IC50 of 175 nM (assayed by displacement of 4′-ethynyl-4-n-[2,3-3H2]- propylbicycloorthobenzoate ([3H]EBOB) from the noncompetitive blocker site).

   

FIPRONIL-SULFONE

FIPRONIL-SULFONE

C12H4Cl2F6N4O2S (451.93362160000004)


A member of the class of pyrazoles that is 1H-pyrazole that is substituted at positions 1, 3, 4, and 5 by 2,6-dichloro-4-(trifluoromethyl)phenyl, cyano, (trifluoromethyl)sulfonyl, and amino groups, respectively. It is a metabolite of the agrochemical fipronil.