Exact Mass: 449.1750756
Exact Mass Matches: 449.1750756
Found 199 metabolites which its exact mass value is equals to given mass value 449.1750756
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Glisoxepide
C20H27N5O5S (449.1732812000001)
Glisoxepide is one of the sulphonamide-derived oral antidiabetic drugs. It inhibits the uptake of bile acids into isolated rat hepatocytes. However it inhibits taurocholate uptake only in the absence of sodium ions. Glisoxepide uptake could be further inhibited by blockers of the hepatocellular monocarboxylate transporter, by the loop diuretic bumetanide, by 4,4-diisothiocyano-2,2-stilbenedisulfonate (DIDS) and by sulphate. These results are consistent with the transport of glisoxepide via the transport system for the unconjugated bile acid cholate. (PMID:1618280, 9017793). A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BB - Sulfonylureas C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C97936 - Sulfonylurea Antidiabetic Agent
N-Ethyl-N-(6,6-dimethyl-2-hepten-4-ynyl)-3-((3,3'-bithiophen-5-yl)methoxy)benzenemethanamine
N-[2,6-Bis(1-methylethyl)phenyl]-N'-[4-[(4-nitrophenyl)thio]phenyl]urea
C25H27N3O3S (449.1773032000001)
4-[[4-[Hydroxy(4-methoxyphenyl)methyl]-5-[(4-hydroxyphenyl)methyl]-1-methyl-1H-imidazol-2-yl]amino]-1-methyl-1H-imidazole-2,5-dione
Ser Thr Asn Glu
C16H27N5O10 (449.17578419999995)
Ala Ala Cys Trp
C20H27N5O5S (449.1732812000001)
Ala Ala Trp Cys
C20H27N5O5S (449.1732812000001)
Ala Cys Ala Trp
C20H27N5O5S (449.1732812000001)
Ala Cys Trp Ala
C20H27N5O5S (449.1732812000001)
Ala Trp Ala Cys
C20H27N5O5S (449.1732812000001)
Ala Trp Cys Ala
C20H27N5O5S (449.1732812000001)
Cys Ala Ala Trp
C20H27N5O5S (449.1732812000001)
Cys Ala Trp Ala
C20H27N5O5S (449.1732812000001)
Cys Cys Lys Pro
Cys Cys Pro Lys
Cys Asp Gly Arg
Cys Asp Arg Gly
Cys Gly Asp Arg
Cys Gly Arg Asp
Cys Lys Cys Pro
Cys Lys Pro Cys
Cys Pro Cys Lys
Cys Pro Lys Cys
Cys Arg Asp Gly
Cys Arg Gly Asp
Cys Trp Ala Ala
C20H27N5O5S (449.1732812000001)
Asp Cys Gly Arg
Asp Cys Arg Gly
Asp Gly Cys Arg
Asp Gly Arg Cys
Asp Asn Thr Thr
C16H27N5O10 (449.17578419999995)
Asp Gln Ser Thr
C16H27N5O10 (449.17578419999995)
Asp Gln Thr Ser
C16H27N5O10 (449.17578419999995)
Asp Arg Cys Gly
Asp Arg Gly Cys
Asp Ser Gln Thr
C16H27N5O10 (449.17578419999995)
Asp Ser Thr Gln
C16H27N5O10 (449.17578419999995)
Asp Thr Asn Thr
C16H27N5O10 (449.17578419999995)
Asp Thr Gln Ser
C16H27N5O10 (449.17578419999995)
Asp Thr Ser Gln
C16H27N5O10 (449.17578419999995)
Asp Thr Thr Asn
C16H27N5O10 (449.17578419999995)
Glu Asn Ser Thr
C16H27N5O10 (449.17578419999995)
Glu Asn Thr Ser
C16H27N5O10 (449.17578419999995)
Glu Gln Ser Ser
C16H27N5O10 (449.17578419999995)
Glu Ser Asn Thr
C16H27N5O10 (449.17578419999995)
Glu Ser Gln Ser
C16H27N5O10 (449.17578419999995)
Glu Ser Ser Gln
C16H27N5O10 (449.17578419999995)
Glu Ser Thr Asn
C16H27N5O10 (449.17578419999995)
Glu Thr Asn Ser
C16H27N5O10 (449.17578419999995)
Glu Thr Ser Asn
C16H27N5O10 (449.17578419999995)
Gly Cys Asp Arg
Gly Cys Arg Asp
Gly Asp Cys Arg
Gly Asp Arg Cys
Gly Gly Met Trp
C20H27N5O5S (449.1732812000001)
Gly Gly Trp Met
C20H27N5O5S (449.1732812000001)
Gly Met Gly Trp
C20H27N5O5S (449.1732812000001)
Gly Met Trp Gly
C20H27N5O5S (449.1732812000001)
Gly Arg Cys Asp
Gly Arg Asp Cys
Gly Trp Gly Met
C20H27N5O5S (449.1732812000001)
Gly Trp Met Gly
C20H27N5O5S (449.1732812000001)
Lys Cys Cys Pro
Lys Cys Pro Cys
Lys Pro Cys Cys
Met Gly Gly Trp
C20H27N5O5S (449.1732812000001)
Met Gly Trp Gly
C20H27N5O5S (449.1732812000001)
Met Trp Gly Gly
C20H27N5O5S (449.1732812000001)
Asn Asp Thr Thr
C16H27N5O10 (449.17578419999995)
Asn Glu Ser Thr
C16H27N5O10 (449.17578419999995)
Asn Glu Thr Ser
C16H27N5O10 (449.17578419999995)
Asn Ser Glu Thr
C16H27N5O10 (449.17578419999995)
Asn Ser Thr Glu
C16H27N5O10 (449.17578419999995)
Asn Thr Asp Thr
C16H27N5O10 (449.17578419999995)
Asn Thr Glu Ser
C16H27N5O10 (449.17578419999995)
Asn Thr Ser Glu
C16H27N5O10 (449.17578419999995)
Asn Thr Thr Asp
C16H27N5O10 (449.17578419999995)
Pro Cys Cys Lys
Pro Cys Lys Cys
Pro Lys Cys Cys
Gln Asp Ser Thr
C16H27N5O10 (449.17578419999995)
Gln Asp Thr Ser
C16H27N5O10 (449.17578419999995)
Gln Glu Ser Ser
C16H27N5O10 (449.17578419999995)
Gln Ser Asp Thr
C16H27N5O10 (449.17578419999995)
Gln Ser Glu Ser
C16H27N5O10 (449.17578419999995)
Gln Ser Ser Glu
C16H27N5O10 (449.17578419999995)
Gln Ser Thr Asp
C16H27N5O10 (449.17578419999995)
Gln Thr Asp Ser
C16H27N5O10 (449.17578419999995)
Gln Thr Ser Asp
C16H27N5O10 (449.17578419999995)
Arg Cys Asp Gly
Arg Cys Gly Asp
Arg Asp Cys Gly
Arg Asp Gly Cys
Arg Gly Cys Asp
Arg Gly Asp Cys
Ser Asp Gln Thr
C16H27N5O10 (449.17578419999995)
Ser Asp Thr Gln
C16H27N5O10 (449.17578419999995)
Ser Glu Asn Thr
C16H27N5O10 (449.17578419999995)
Ser Glu Gln Ser
C16H27N5O10 (449.17578419999995)
Ser Glu Ser Gln
C16H27N5O10 (449.17578419999995)
Ser Glu Thr Asn
C16H27N5O10 (449.17578419999995)
Ser Asn Glu Thr
C16H27N5O10 (449.17578419999995)
Ser Asn Thr Glu
C16H27N5O10 (449.17578419999995)
Ser Gln Asp Thr
C16H27N5O10 (449.17578419999995)
Ser Gln Glu Ser
C16H27N5O10 (449.17578419999995)
Ser Gln Ser Glu
C16H27N5O10 (449.17578419999995)
Ser Gln Thr Asp
C16H27N5O10 (449.17578419999995)
Ser Ser Glu Gln
C16H27N5O10 (449.17578419999995)
Ser Ser Gln Glu
C16H27N5O10 (449.17578419999995)
Ser Thr Asp Gln
C16H27N5O10 (449.17578419999995)
Ser Thr Glu Asn
C16H27N5O10 (449.17578419999995)
Ser Thr Gln Asp
C16H27N5O10 (449.17578419999995)
Thr Asp Asn Thr
C16H27N5O10 (449.17578419999995)
Thr Asp Gln Ser
C16H27N5O10 (449.17578419999995)
Thr Asp Ser Gln
C16H27N5O10 (449.17578419999995)
Thr Asp Thr Asn
C16H27N5O10 (449.17578419999995)
Thr Glu Asn Ser
C16H27N5O10 (449.17578419999995)
Thr Glu Ser Asn
C16H27N5O10 (449.17578419999995)
Thr Asn Asp Thr
C16H27N5O10 (449.17578419999995)
Thr Asn Glu Ser
C16H27N5O10 (449.17578419999995)
Thr Asn Ser Glu
C16H27N5O10 (449.17578419999995)
Thr Asn Thr Asp
C16H27N5O10 (449.17578419999995)
Thr Gln Asp Ser
C16H27N5O10 (449.17578419999995)
Thr Gln Ser Asp
C16H27N5O10 (449.17578419999995)
Thr Ser Asp Gln
C16H27N5O10 (449.17578419999995)
Thr Ser Glu Asn
C16H27N5O10 (449.17578419999995)
Thr Ser Asn Glu
C16H27N5O10 (449.17578419999995)
Thr Ser Gln Asp
C16H27N5O10 (449.17578419999995)
Thr Thr Asp Asn
C16H27N5O10 (449.17578419999995)
Thr Thr Asn Asp
C16H27N5O10 (449.17578419999995)
Trp Ala Ala Cys
C20H27N5O5S (449.1732812000001)
Trp Ala Cys Ala
C20H27N5O5S (449.1732812000001)
Trp Cys Ala Ala
C20H27N5O5S (449.1732812000001)
Trp Gly Gly Met
C20H27N5O5S (449.1732812000001)
Trp Gly Met Gly
C20H27N5O5S (449.1732812000001)
Trp Met Gly Gly
C20H27N5O5S (449.1732812000001)
Glisoxepid
C20H27N5O5S (449.1732812000001)
A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BB - Sulfonylureas C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C97936 - Sulfonylurea Antidiabetic Agent
4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenyl-butyric acid
C27H28ClNO3 (449.17576080000003)
(E)-N-ethyl-6,6-dimethyl-N-[[3-[(4-thiophen-3-ylthiophen-2-yl)methoxy]phenyl]methyl]hept-2-en-4-yn-1-amine
NB-598 is a potent and competitive inhibitor of squalene epoxidase (SE), and suppresses triglyceride biosynthesis through the farnesol pathway. NB-598 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
N-[2,6-Bis(1-methylethyl)phenyl]-N-[4-[(4-nitrophenyl)thio]phenyl]urea
C25H27N3O3S (449.1773032000001)
VULM 1457 is a potent inhibitor of cholesterol acyltransferase (acyl-CoA). VULM1457 significantly reduces production and secretion of adrenomedullin (AM) and down-regulates AM receptors on human hepatoblastic cells. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM 1457 has the potential for the research of diabetes mellitus and hypercholesterolaemia[1][2].
N-(3,5-dimethylphenyl)-2-[[4-(4-fluorophenyl)-5-[(1-methyl-2-pyrrolyl)methyl]-1,2,4-triazol-3-yl]thio]acetamide
N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide
N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamide
C25H27N3O3S (449.1773032000001)
trans-4-[({2-[(2-oxo-3-phenyl-2H-chromen-7-yl)oxy]propanoyl}amino)methyl]cyclohexanecarboxylic acid
C26H27NO6 (449.18382820000005)
N-[3-(3,5-dimethyl-1-pyrazolyl)-2-hydroxypropyl]-N-(4-methylphenyl)-2-naphthalenesulfonamide
C25H27N3O3S (449.1773032000001)
(2S,3S,3aR,9bR)-7-(2-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(pyridin-4-ylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester
methyl (2S,3S,3aR,9bR)-1-[(3-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-7-pyridin-3-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylate
methyl (1R,9S,10S,11S)-5-(4-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylate
methyl (1S,9R,10R,11R)-5-(4-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylate
(2R,3R,3aS,9bS)-7-(2-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(pyridin-4-ylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester
(2R,3R,3aS,9bS)-1-[(3-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-7-(3-pyridinyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester
(2r,3r,4s,5s,6r)-2-{[(1s,17s,18s,19r)-17-hydroxy-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraen-18-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
2-({17-hydroxy-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraen-18-yl}oxy)-6-(hydroxymethyl)oxane-3,4,5-triol
(2r,3s,4r,5s,6r)-2-{[(1r,17s,18s,19r)-17-hydroxy-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraen-18-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
(4r,8r,10s,18r,19r)-18-(furan-3-yl)-10-hydroxy-4,9,9,19-tetramethyl-5,17-dioxa-2-azapentacyclo[11.8.0.0³,¹¹.0⁴,⁸.0¹⁴,¹⁹]henicosa-1(13),2,11,14-tetraene-6,16-dione
C26H27NO6 (449.18382820000005)
(4s,8s,10r,18r,19r)-18-(furan-3-yl)-10-hydroxy-4,9,9,19-tetramethyl-5,17-dioxa-2-azapentacyclo[11.8.0.0³,¹¹.0⁴,⁸.0¹⁴,¹⁹]henicosa-1(13),2,11,14-tetraene-6,16-dione
C26H27NO6 (449.18382820000005)
18-(furan-3-yl)-10-hydroxy-4,9,9,19-tetramethyl-5,17-dioxa-2-azapentacyclo[11.8.0.0³,¹¹.0⁴,⁸.0¹⁴,¹⁹]henicosa-1,3(11),12,14-tetraene-6,16-dione
C26H27NO6 (449.18382820000005)