Exact Mass: 449.1699
Exact Mass Matches: 449.1699
Found 204 metabolites which its exact mass value is equals to given mass value 449.1699
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Glisoxepide
Glisoxepide is one of the sulphonamide-derived oral antidiabetic drugs. It inhibits the uptake of bile acids into isolated rat hepatocytes. However it inhibits taurocholate uptake only in the absence of sodium ions. Glisoxepide uptake could be further inhibited by blockers of the hepatocellular monocarboxylate transporter, by the loop diuretic bumetanide, by 4,4-diisothiocyano-2,2-stilbenedisulfonate (DIDS) and by sulphate. These results are consistent with the transport of glisoxepide via the transport system for the unconjugated bile acid cholate. (PMID:1618280, 9017793). A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BB - Sulfonylureas C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C97936 - Sulfonylurea Antidiabetic Agent
N-[2,6-Bis(1-methylethyl)phenyl]-N'-[4-[(4-nitrophenyl)thio]phenyl]urea
4-(tert-Butyl)-N-({[2-methyl-5-(morpholinosulfonyl)-3-furyl]carbonyl}oxy)benzenecarboximidamide
4-[[4-[Hydroxy(4-methoxyphenyl)methyl]-5-[(4-hydroxyphenyl)methyl]-1-methyl-1H-imidazol-2-yl]amino]-1-methyl-1H-imidazole-2,5-dione
Ser Thr Asn Glu
Ala Ala Cys Trp
Ala Ala Trp Cys
Ala Cys Ala Trp
Ala Cys Trp Ala
Ala Trp Ala Cys
Ala Trp Cys Ala
Cys Ala Ala Trp
Cys Ala Trp Ala
Cys Cys Lys Pro
Cys Cys Pro Lys
Cys Asp Gly Arg
Cys Asp Arg Gly
Cys Gly Asp Arg
Cys Gly Arg Asp
Cys Lys Cys Pro
Cys Lys Pro Cys
Cys Pro Cys Lys
Cys Pro Lys Cys
Cys Arg Asp Gly
Cys Arg Gly Asp
Cys Trp Ala Ala
Asp Cys Gly Arg
Asp Cys Arg Gly
Asp Gly Cys Arg
Asp Gly Arg Cys
Asp Asn Thr Thr
Asp Gln Ser Thr
Asp Gln Thr Ser
Asp Arg Cys Gly
Asp Arg Gly Cys
Asp Ser Gln Thr
Asp Ser Thr Gln
Asp Thr Asn Thr
Asp Thr Gln Ser
Asp Thr Ser Gln
Asp Thr Thr Asn
Glu Asn Ser Thr
Glu Asn Thr Ser
Glu Gln Ser Ser
Glu Ser Asn Thr
Glu Ser Gln Ser
Glu Ser Ser Gln
Glu Ser Thr Asn
Glu Thr Asn Ser
Glu Thr Ser Asn
Gly Cys Asp Arg
Gly Cys Arg Asp
Gly Asp Cys Arg
Gly Asp Arg Cys
Gly Gly Met Trp
Gly Gly Trp Met
Gly Met Gly Trp
Gly Met Trp Gly
Gly Arg Cys Asp
Gly Arg Asp Cys
Gly Trp Gly Met
Gly Trp Met Gly
Lys Cys Cys Pro
Lys Cys Pro Cys
Lys Pro Cys Cys
Met Gly Gly Trp
Met Gly Trp Gly
Met Trp Gly Gly
Asn Asp Thr Thr
Asn Glu Ser Thr
Asn Glu Thr Ser
Asn Ser Glu Thr
Asn Ser Thr Glu
Asn Thr Asp Thr
Asn Thr Glu Ser
Asn Thr Ser Glu
Asn Thr Thr Asp
Pro Cys Cys Lys
Pro Cys Lys Cys
Pro Lys Cys Cys
Gln Asp Ser Thr
Gln Asp Thr Ser
Gln Glu Ser Ser
Gln Ser Asp Thr
Gln Ser Glu Ser
Gln Ser Ser Glu
Gln Ser Thr Asp
Gln Thr Asp Ser
Gln Thr Ser Asp
Arg Cys Asp Gly
Arg Cys Gly Asp
Arg Asp Cys Gly
Arg Asp Gly Cys
Arg Gly Cys Asp
Arg Gly Asp Cys
Ser Asp Gln Thr
Ser Asp Thr Gln
Ser Glu Asn Thr
Ser Glu Gln Ser
Ser Glu Ser Gln
Ser Glu Thr Asn
Ser Asn Glu Thr
Ser Asn Thr Glu
Ser Gln Asp Thr
Ser Gln Glu Ser
Ser Gln Ser Glu
Ser Gln Thr Asp
Ser Ser Glu Gln
Ser Ser Gln Glu
Ser Thr Asp Gln
Ser Thr Glu Asn
Ser Thr Gln Asp
Thr Asp Asn Thr
Thr Asp Gln Ser
Thr Asp Ser Gln
Thr Asp Thr Asn
Thr Glu Asn Ser
Thr Glu Ser Asn
Thr Asn Asp Thr
Thr Asn Glu Ser
Thr Asn Ser Glu
Thr Asn Thr Asp
Thr Gln Asp Ser
Thr Gln Ser Asp
Thr Ser Asp Gln
Thr Ser Glu Asn
Thr Ser Asn Glu
Thr Ser Gln Asp
Thr Thr Asp Asn
Thr Thr Asn Asp
Trp Ala Ala Cys
Trp Ala Cys Ala
Trp Cys Ala Ala
Trp Gly Gly Met
Trp Gly Met Gly
Trp Met Gly Gly
Glisoxepid
A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BB - Sulfonylureas C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C97936 - Sulfonylurea Antidiabetic Agent
Sarmoxicillin
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenyl-butyric acid
N-[2,6-Bis(1-methylethyl)phenyl]-N-[4-[(4-nitrophenyl)thio]phenyl]urea
VULM 1457 is a potent inhibitor of cholesterol acyltransferase (acyl-CoA). VULM1457 significantly reduces production and secretion of adrenomedullin (AM) and down-regulates AM receptors on human hepatoblastic cells. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM 1457 has the potential for the research of diabetes mellitus and hypercholesterolaemia[1][2].
N-(3,5-dimethylphenyl)-2-[[4-(4-fluorophenyl)-5-[(1-methyl-2-pyrrolyl)methyl]-1,2,4-triazol-3-yl]thio]acetamide
N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide
N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamide
N-[3-(3,5-dimethyl-1-pyrazolyl)-2-hydroxypropyl]-N-(4-methylphenyl)-2-naphthalenesulfonamide
(2S,3S,3aR,9bR)-7-(2-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(pyridin-4-ylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester
methyl (2S,3S,3aR,9bR)-1-[(3-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-7-pyridin-3-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylate
methyl (1R,9S,10S,11S)-5-(4-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylate
2-[(2R,5S,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
2-[(2S,5S,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
2-[(2S,5R,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
methyl (1S,9R,10R,11R)-5-(4-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylate
2-[(2S,5R,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
2-[(2R,5R,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
2-[(2S,5S,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
2-[(2R,5R,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
2-[(2R,5S,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
(2R,3R,3aS,9bS)-7-(2-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(pyridin-4-ylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester
(2R,3R,3aS,9bS)-1-[(3-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-7-(3-pyridinyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester
OPC-14523 (hydrochloride)
OPC-14523 hydrochloride is an orally active sigma and 5-HT1A receptor agonist, with high affinity for sigma receptors (σ1/2 IC50=47/56 nM), the 5-HT1A receptor (IC50=2.3 nM), and the 5-HT transporter (IC50=80 nM). OPC-14523 hydrochloride shows antidepressant-like activity[1][2].