Exact Mass: 449.1693

Exact Mass Matches: 449.1693

Found 205 metabolites which its exact mass value is equals to given mass value 449.1693, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

   

Glisoxepide

N-{2-[4-({[(azepan-1-yl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-5-methyl-1,2-oxazole-3-carboxamide

C20H27N5O5S (449.1733)


Glisoxepide is one of the sulphonamide-derived oral antidiabetic drugs. It inhibits the uptake of bile acids into isolated rat hepatocytes. However it inhibits taurocholate uptake only in the absence of sodium ions. Glisoxepide uptake could be further inhibited by blockers of the hepatocellular monocarboxylate transporter, by the loop diuretic bumetanide, by 4,4-diisothiocyano-2,2-stilbenedisulfonate (DIDS) and by sulphate. These results are consistent with the transport of glisoxepide via the transport system for the unconjugated bile acid cholate. (PMID:1618280, 9017793). A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BB - Sulfonylureas C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C97936 - Sulfonylurea Antidiabetic Agent

   

N-[2,6-Bis(1-methylethyl)phenyl]-N'-[4-[(4-nitrophenyl)thio]phenyl]urea

N-[2,6-bis(propan-2-yl)phenyl]-N-{4-[(4-nitrophenyl)sulphanyl]phenyl}carbamimidic acid

C25H27N3O3S (449.1773)


   

Lycorine-1-O-beta-D-glucoside

Lycorine-1-O-beta-D-glucoside

C22H27NO9 (449.1686)


   

4-(tert-Butyl)-N-({[2-methyl-5-(morpholinosulfonyl)-3-furyl]carbonyl}oxy)benzenecarboximidamide

4-(tert-Butyl)-N-({[2-methyl-5-(morpholinosulfonyl)-3-furyl]carbonyl}oxy)benzenecarboximidamide

C21H27N3O6S (449.162)


   

4-[[4-[Hydroxy(4-methoxyphenyl)methyl]-5-[(4-hydroxyphenyl)methyl]-1-methyl-1H-imidazol-2-yl]amino]-1-methyl-1H-imidazole-2,5-dione

4-[[4-[Hydroxy(4-methoxyphenyl)methyl]-5-[(4-hydroxyphenyl)methyl]-1-methyl-1H-imidazol-2-yl]amino]-1-methyl-1H-imidazole-2,5-dione

C23H23N5O5 (449.1699)


   
   

Gly Thr Gly Glu Ser

Gly Thr Gly Glu Ser

C16H27N5O10 (449.1758)


   
   
   
   

Ser Thr Asn Glu

(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-hydroxybutanamido]-3-carbamoylpropanamido]pentanedioic acid

C16H27N5O10 (449.1758)


   
   
   
   

Ala Ala Cys Trp

(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-aminopropanamido]propanamido]-3-sulfanylpropanamido]-3-(1H-indol-3-yl)propanoic acid

C20H27N5O5S (449.1733)


   

Ala Ala Trp Cys

(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]propanamido]-3-(1H-indol-3-yl)propanamido]-3-sulfanylpropanoic acid

C20H27N5O5S (449.1733)


   

Ala Cys Ala Trp

(2S)-2-[(2S)-2-[(2R)-2-[(2S)-2-aminopropanamido]-3-sulfanylpropanamido]propanamido]-3-(1H-indol-3-yl)propanoic acid

C20H27N5O5S (449.1733)


   

Ala Cys Trp Ala

(2S)-2-[(2S)-2-[(2R)-2-[(2S)-2-aminopropanamido]-3-sulfanylpropanamido]-3-(1H-indol-3-yl)propanamido]propanoic acid

C20H27N5O5S (449.1733)


   

Ala Trp Ala Cys

(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-sulfanylpropanoic acid

C20H27N5O5S (449.1733)


   

Ala Trp Cys Ala

(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-(1H-indol-3-yl)propanamido]-3-sulfanylpropanamido]propanoic acid

C20H27N5O5S (449.1733)


   

Cys Ala Ala Trp

(2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]propanamido]propanamido]-3-(1H-indol-3-yl)propanoic acid

C20H27N5O5S (449.1733)


   

Cys Ala Trp Ala

(2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]propanamido]-3-(1H-indol-3-yl)propanamido]propanoic acid

C20H27N5O5S (449.1733)


   

Cys Cys Lys Pro

(2S)-1-[(2S)-6-amino-2-[(2R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-sulfanylpropanamido]hexanoyl]pyrrolidine-2-carboxylic acid

C17H31N5O5S2 (449.1767)


   

Cys Cys Pro Lys

(2S)-6-amino-2-{[(2S)-1-[(2R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-sulfanylpropanoyl]pyrrolidin-2-yl]formamido}hexanoic acid

C17H31N5O5S2 (449.1767)


   

Cys Asp Gly Arg

(2S)-2-{2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-carboxypropanamido]acetamido}-5-carbamimidamidopentanoic acid

C15H27N7O7S (449.1693)


   

Cys Asp Arg Gly

(3S)-3-[(2R)-2-amino-3-sulfanylpropanamido]-3-{[(1S)-4-carbamimidamido-1-[(carboxymethyl)carbamoyl]butyl]carbamoyl}propanoic acid

C15H27N7O7S (449.1693)


   

Cys Gly Asp Arg

(2S)-2-[(2S)-2-{2-[(2R)-2-amino-3-sulfanylpropanamido]acetamido}-3-carboxypropanamido]-5-carbamimidamidopentanoic acid

C15H27N7O7S (449.1693)


   

Cys Gly Arg Asp

(2S)-2-[(2S)-2-{2-[(2R)-2-amino-3-sulfanylpropanamido]acetamido}-5-carbamimidamidopentanamido]butanedioic acid

C15H27N7O7S (449.1693)


   

Cys Lys Cys Pro

(2S)-1-[(2R)-2-[(2S)-6-amino-2-[(2R)-2-amino-3-sulfanylpropanamido]hexanamido]-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid

C17H31N5O5S2 (449.1767)


   

Cys Lys Pro Cys

(2R)-2-{[(2S)-1-[(2S)-6-amino-2-[(2R)-2-amino-3-sulfanylpropanamido]hexanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid

C17H31N5O5S2 (449.1767)


   

Cys Pro Cys Lys

(2S)-6-amino-2-[(2R)-2-{[(2S)-1-[(2R)-2-amino-3-sulfanylpropanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]hexanoic acid

C17H31N5O5S2 (449.1767)


   

Cys Pro Lys Cys

(2R)-2-[(2S)-6-amino-2-{[(2S)-1-[(2R)-2-amino-3-sulfanylpropanoyl]pyrrolidin-2-yl]formamido}hexanamido]-3-sulfanylpropanoic acid

C17H31N5O5S2 (449.1767)


   

Cys Arg Asp Gly

(3S)-3-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-5-carbamimidamidopentanamido]-3-[(carboxymethyl)carbamoyl]propanoic acid

C15H27N7O7S (449.1693)


   

Cys Arg Gly Asp

(2S)-2-{2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-5-carbamimidamidopentanamido]acetamido}butanedioic acid

C15H27N7O7S (449.1693)


   

Cys Trp Ala Ala

(2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid

C20H27N5O5S (449.1733)


   

Asp Cys Gly Arg

(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-carboxypropanamido]-3-sulfanylpropanamido]acetamido}-5-carbamimidamidopentanoic acid

C15H27N7O7S (449.1693)


   

Asp Cys Arg Gly

(3S)-3-amino-3-{[(1R)-1-{[(1S)-4-carbamimidamido-1-[(carboxymethyl)carbamoyl]butyl]carbamoyl}-2-sulfanylethyl]carbamoyl}propanoic acid

C15H27N7O7S (449.1693)


   

Asp Gly Cys Arg

(2S)-2-[(2R)-2-{2-[(2S)-2-amino-3-carboxypropanamido]acetamido}-3-sulfanylpropanamido]-5-carbamimidamidopentanoic acid

C15H27N7O7S (449.1693)


   

Asp Gly Arg Cys

(3S)-3-amino-3-[({[(1S)-4-carbamimidamido-1-{[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}butyl]carbamoyl}methyl)carbamoyl]propanoic acid

C15H27N7O7S (449.1693)


   

Asp Asn Thr Thr

(2S,3R)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-3-carbamoylpropanamido]-3-hydroxybutanamido]-3-hydroxybutanoic acid

C16H27N5O10 (449.1758)


   

Asp Gln Ser Thr

(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-4-carbamoylbutanamido]-3-hydroxypropanamido]-3-hydroxybutanoic acid

C16H27N5O10 (449.1758)


   

Asp Gln Thr Ser

(3S)-3-amino-3-{[(1S)-3-carbamoyl-1-{[(1S,2R)-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]carbamoyl}propanoic acid

C16H27N5O10 (449.1758)


   

Asp Arg Cys Gly

(3S)-3-amino-3-{[(1S)-4-carbamimidamido-1-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl]carbamoyl}butyl]carbamoyl}propanoic acid

C15H27N7O7S (449.1693)


   

Asp Arg Gly Cys

(3S)-3-amino-3-{[(1S)-4-carbamimidamido-1-[({[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}methyl)carbamoyl]butyl]carbamoyl}propanoic acid

C15H27N7O7S (449.1693)


   

Asp Ser Gln Thr

(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-3-hydroxypropanamido]-4-carbamoylbutanamido]-3-hydroxybutanoic acid

C16H27N5O10 (449.1758)


   

Asp Ser Thr Gln

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-3-hydroxypropanamido]-3-hydroxybutanamido]-4-carbamoylbutanoic acid

C16H27N5O10 (449.1758)


   

Asp Thr Asn Thr

(2S,3R)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-3-carboxypropanamido]-3-hydroxybutanamido]-3-carbamoylpropanamido]-3-hydroxybutanoic acid

C16H27N5O10 (449.1758)


   

Asp Thr Gln Ser

(3S)-3-amino-3-{[(1S,2R)-1-{[(1S)-3-carbamoyl-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propanoic acid

C16H27N5O10 (449.1758)


   

Asp Thr Ser Gln

(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-3-carboxypropanamido]-3-hydroxybutanamido]-3-hydroxypropanamido]-4-carbamoylbutanoic acid

C16H27N5O10 (449.1758)


   

Asp Thr Thr Asn

(2S)-2-[(2S,3R)-2-[(2S,3R)-2-[(2S)-2-amino-3-carboxypropanamido]-3-hydroxybutanamido]-3-hydroxybutanamido]-3-carbamoylpropanoic acid

C16H27N5O10 (449.1758)


   

Glu Asn Ser Thr

(4S)-4-amino-4-{[(1S)-2-carbamoyl-1-{[(1S)-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-2-hydroxyethyl]carbamoyl}ethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Glu Asn Thr Ser

(4S)-4-amino-4-{[(1S)-2-carbamoyl-1-{[(1S,2R)-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}ethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Glu Gln Ser Ser

(4S)-4-amino-4-{[(1S)-3-carbamoyl-1-{[(1S)-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}propyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Glu Ser Asn Thr

(4S)-4-amino-4-{[(1S)-1-{[(1S)-2-carbamoyl-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}ethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Glu Ser Gln Ser

(4S)-4-amino-4-{[(1S)-1-{[(1S)-3-carbamoyl-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}propyl]carbamoyl}-2-hydroxyethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Glu Ser Ser Gln

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carboxybutanamido]-3-hydroxypropanamido]-3-hydroxypropanamido]-4-carbamoylbutanoic acid

C16H27N5O10 (449.1758)


   

Glu Ser Thr Asn

(4S)-4-amino-4-{[(1S)-1-{[(1S,2R)-1-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-2-hydroxyethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Glu Thr Asn Ser

(4S)-4-amino-4-{[(1S,2R)-1-{[(1S)-2-carbamoyl-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Glu Thr Ser Asn

(4S)-4-amino-4-{[(1S,2R)-1-{[(1S)-1-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Gly Cys Asp Arg

(2S)-2-[(2S)-2-[(2R)-2-(2-aminoacetamido)-3-sulfanylpropanamido]-3-carboxypropanamido]-5-carbamimidamidopentanoic acid

C15H27N7O7S (449.1693)


   

Gly Cys Arg Asp

(2S)-2-[(2S)-2-[(2R)-2-(2-aminoacetamido)-3-sulfanylpropanamido]-5-carbamimidamidopentanamido]butanedioic acid

C15H27N7O7S (449.1693)


   

Gly Asp Cys Arg

(2S)-2-[(2R)-2-[(2S)-2-(2-aminoacetamido)-3-carboxypropanamido]-3-sulfanylpropanamido]-5-carbamimidamidopentanoic acid

C15H27N7O7S (449.1693)


   

Gly Asp Arg Cys

(3S)-3-(2-aminoacetamido)-3-{[(1S)-4-carbamimidamido-1-{[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}butyl]carbamoyl}propanoic acid

C15H27N7O7S (449.1693)


   

Gly Gly Met Trp

(2S)-2-[(2S)-2-[2-(2-aminoacetamido)acetamido]-4-(methylsulfanyl)butanamido]-3-(1H-indol-3-yl)propanoic acid

C20H27N5O5S (449.1733)


   

Gly Gly Trp Met

(2S)-2-[(2S)-2-[2-(2-aminoacetamido)acetamido]-3-(1H-indol-3-yl)propanamido]-4-(methylsulfanyl)butanoic acid

C20H27N5O5S (449.1733)


   

Gly Met Gly Trp

(2S)-2-{2-[(2S)-2-(2-aminoacetamido)-4-(methylsulfanyl)butanamido]acetamido}-3-(1H-indol-3-yl)propanoic acid

C20H27N5O5S (449.1733)


   

Gly Met Trp Gly

2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-4-(methylsulfanyl)butanamido]-3-(1H-indol-3-yl)propanamido]acetic acid

C20H27N5O5S (449.1733)


   

Gly Arg Cys Asp

(2S)-2-[(2R)-2-[(2S)-2-(2-aminoacetamido)-5-carbamimidamidopentanamido]-3-sulfanylpropanamido]butanedioic acid

C15H27N7O7S (449.1693)


   

Gly Arg Asp Cys

(3S)-3-[(2S)-2-(2-aminoacetamido)-5-carbamimidamidopentanamido]-3-{[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}propanoic acid

C15H27N7O7S (449.1693)


   

Gly Trp Gly Met

(2S)-2-{2-[(2S)-2-(2-aminoacetamido)-3-(1H-indol-3-yl)propanamido]acetamido}-4-(methylsulfanyl)butanoic acid

C20H27N5O5S (449.1733)


   

Gly Trp Met Gly

2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-indol-3-yl)propanamido]-4-(methylsulfanyl)butanamido]acetic acid

C20H27N5O5S (449.1733)


   
   
   

Lys Cys Cys Pro

(2S)-1-[(2R)-2-[(2R)-2-[(2S)-2,6-diaminohexanamido]-3-sulfanylpropanamido]-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid

C17H31N5O5S2 (449.1767)


   

Lys Cys Pro Cys

(2R)-2-{[(2S)-1-[(2R)-2-[(2S)-2,6-diaminohexanamido]-3-sulfanylpropanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanoic acid

C17H31N5O5S2 (449.1767)


   
   

Lys Pro Cys Cys

(2R)-2-[(2R)-2-{[(2S)-1-[(2S)-2,6-diaminohexanoyl]pyrrolidin-2-yl]formamido}-3-sulfanylpropanamido]-3-sulfanylpropanoic acid

C17H31N5O5S2 (449.1767)


   
   
   

Met Gly Gly Trp

(2S)-2-(2-{2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]acetamido}acetamido)-3-(1H-indol-3-yl)propanoic acid

C20H27N5O5S (449.1733)


   

Met Gly Trp Gly

2-[(2S)-2-{2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]acetamido}-3-(1H-indol-3-yl)propanamido]acetic acid

C20H27N5O5S (449.1733)


   
   

Met Trp Gly Gly

2-{2-[(2S)-2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]-3-(1H-indol-3-yl)propanamido]acetamido}acetic acid

C20H27N5O5S (449.1733)


   

Asn Asp Thr Thr

(2S,3R)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-carboxypropanamido]-3-hydroxybutanamido]-3-hydroxybutanoic acid

C16H27N5O10 (449.1758)


   

Asn Glu Ser Thr

(4S)-4-[(2S)-2-amino-3-carbamoylpropanamido]-4-{[(1S)-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}-2-hydroxyethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Asn Glu Thr Ser

(4S)-4-[(2S)-2-amino-3-carbamoylpropanamido]-4-{[(1S,2R)-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Asn Ser Glu Thr

(4S)-4-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-hydroxypropanamido]-4-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Asn Ser Thr Glu

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-hydroxypropanamido]-3-hydroxybutanamido]pentanedioic acid

C16H27N5O10 (449.1758)


   

Asn Thr Asp Thr

(2S,3R)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-hydroxybutanamido]-3-carboxypropanamido]-3-hydroxybutanoic acid

C16H27N5O10 (449.1758)


   

Asn Thr Glu Ser

(4S)-4-[(2S,3R)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-hydroxybutanamido]-4-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Asn Thr Ser Glu

(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-hydroxybutanamido]-3-hydroxypropanamido]pentanedioic acid

C16H27N5O10 (449.1758)


   

Asn Thr Thr Asp

(2S)-2-[(2S,3R)-2-[(2S,3R)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-hydroxybutanamido]-3-hydroxybutanamido]butanedioic acid

C16H27N5O10 (449.1758)


   

Pro Cys Cys Lys

(2S)-6-amino-2-[(2R)-2-[(2R)-2-[(2S)-pyrrolidin-2-ylformamido]-3-sulfanylpropanamido]-3-sulfanylpropanamido]hexanoic acid

C17H31N5O5S2 (449.1767)


   

Pro Cys Lys Cys

(2R)-2-[(2S)-6-amino-2-[(2R)-2-[(2S)-pyrrolidin-2-ylformamido]-3-sulfanylpropanamido]hexanamido]-3-sulfanylpropanoic acid

C17H31N5O5S2 (449.1767)


   
   

Pro Lys Cys Cys

(2R)-2-[(2R)-2-[(2S)-6-amino-2-[(2S)-pyrrolidin-2-ylformamido]hexanamido]-3-sulfanylpropanamido]-3-sulfanylpropanoic acid

C17H31N5O5S2 (449.1767)


   
   

Gln Asp Ser Thr

(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-carboxypropanamido]-3-hydroxypropanamido]-3-hydroxybutanoic acid

C16H27N5O10 (449.1758)


   

Gln Asp Thr Ser

(3S)-3-[(2S)-2-amino-4-carbamoylbutanamido]-3-{[(1S,2R)-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propanoic acid

C16H27N5O10 (449.1758)


   

Gln Glu Ser Ser

(4S)-4-[(2S)-2-amino-4-carbamoylbutanamido]-4-{[(1S)-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Gln Ser Asp Thr

(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxypropanamido]-3-carboxypropanamido]-3-hydroxybutanoic acid

C16H27N5O10 (449.1758)


   

Gln Ser Glu Ser

(4S)-4-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxypropanamido]-4-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Gln Ser Ser Glu

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxypropanamido]-3-hydroxypropanamido]pentanedioic acid

C16H27N5O10 (449.1758)


   

Gln Ser Thr Asp

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxypropanamido]-3-hydroxybutanamido]butanedioic acid

C16H27N5O10 (449.1758)


   

Gln Thr Asp Ser

(3S)-3-[(2S,3R)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxybutanamido]-3-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}propanoic acid

C16H27N5O10 (449.1758)


   

Gln Thr Ser Asp

(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-4-carbamoylbutanamido]-3-hydroxybutanamido]-3-hydroxypropanamido]butanedioic acid

C16H27N5O10 (449.1758)


   

Arg Cys Asp Gly

(3S)-3-[(2R)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-sulfanylpropanamido]-3-[(carboxymethyl)carbamoyl]propanoic acid

C15H27N7O7S (449.1693)


   

Arg Cys Gly Asp

(2S)-2-{2-[(2R)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-sulfanylpropanamido]acetamido}butanedioic acid

C15H27N7O7S (449.1693)


   

Arg Asp Cys Gly

(3S)-3-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl]carbamoyl}propanoic acid

C15H27N7O7S (449.1693)


   

Arg Asp Gly Cys

(3S)-3-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-[({[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}methyl)carbamoyl]propanoic acid

C15H27N7O7S (449.1693)


   

Arg Gly Cys Asp

(2S)-2-[(2R)-2-{2-[(2S)-2-amino-5-carbamimidamidopentanamido]acetamido}-3-sulfanylpropanamido]butanedioic acid

C15H27N7O7S (449.1693)


   

Arg Gly Asp Cys

(3S)-3-{2-[(2S)-2-amino-5-carbamimidamidopentanamido]acetamido}-3-{[(1R)-1-carboxy-2-sulfanylethyl]carbamoyl}propanoic acid

C15H27N7O7S (449.1693)


   
   
   

Ser Asp Gln Thr

(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-carboxypropanamido]-4-carbamoylbutanamido]-3-hydroxybutanoic acid

C16H27N5O10 (449.1758)


   

Ser Asp Thr Gln

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-carboxypropanamido]-3-hydroxybutanamido]-4-carbamoylbutanoic acid

C16H27N5O10 (449.1758)


   

Ser Glu Asn Thr

(4S)-4-[(2S)-2-amino-3-hydroxypropanamido]-4-{[(1S)-2-carbamoyl-1-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}ethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Ser Glu Gln Ser

(4S)-4-[(2S)-2-amino-3-hydroxypropanamido]-4-{[(1S)-3-carbamoyl-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}propyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Ser Glu Ser Gln

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-4-carboxybutanamido]-3-hydroxypropanamido]-4-carbamoylbutanoic acid

C16H27N5O10 (449.1758)


   

Ser Glu Thr Asn

(4S)-4-[(2S)-2-amino-3-hydroxypropanamido]-4-{[(1S,2R)-1-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Ser Asn Glu Thr

(4S)-4-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-carbamoylpropanamido]-4-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Ser Asn Thr Glu

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-carbamoylpropanamido]-3-hydroxybutanamido]pentanedioic acid

C16H27N5O10 (449.1758)


   
   

Ser Gln Asp Thr

(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-4-carbamoylbutanamido]-3-carboxypropanamido]-3-hydroxybutanoic acid

C16H27N5O10 (449.1758)


   

Ser Gln Glu Ser

(4S)-4-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-4-carbamoylbutanamido]-4-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Ser Gln Ser Glu

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-4-carbamoylbutanamido]-3-hydroxypropanamido]pentanedioic acid

C16H27N5O10 (449.1758)


   

Ser Gln Thr Asp

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-4-carbamoylbutanamido]-3-hydroxybutanamido]butanedioic acid

C16H27N5O10 (449.1758)


   

Ser Ser Glu Gln

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-hydroxypropanamido]-4-carboxybutanamido]-4-carbamoylbutanoic acid

C16H27N5O10 (449.1758)


   

Ser Ser Gln Glu

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-hydroxypropanamido]-4-carbamoylbutanamido]pentanedioic acid

C16H27N5O10 (449.1758)


   

Ser Thr Asp Gln

(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-hydroxybutanamido]-3-carboxypropanamido]-4-carbamoylbutanoic acid

C16H27N5O10 (449.1758)


   

Ser Thr Glu Asn

(4S)-4-[(2S,3R)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-hydroxybutanamido]-4-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Ser Thr Gln Asp

(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-hydroxybutanamido]-4-carbamoylbutanamido]butanedioic acid

C16H27N5O10 (449.1758)


   

Thr Asp Asn Thr

(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-carboxypropanamido]-3-carbamoylpropanamido]-3-hydroxybutanoic acid

C16H27N5O10 (449.1758)


   

Thr Asp Gln Ser

(3S)-3-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-{[(1S)-3-carbamoyl-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}propyl]carbamoyl}propanoic acid

C16H27N5O10 (449.1758)


   

Thr Asp Ser Gln

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-carboxypropanamido]-3-hydroxypropanamido]-4-carbamoylbutanoic acid

C16H27N5O10 (449.1758)


   

Thr Asp Thr Asn

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-carboxypropanamido]-3-hydroxybutanamido]-3-carbamoylpropanoic acid

C16H27N5O10 (449.1758)


   
   

Thr Glu Asn Ser

(4S)-4-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-{[(1S)-2-carbamoyl-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}ethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Thr Glu Ser Asn

(4S)-4-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-{[(1S)-1-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Thr Asn Asp Thr

(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-carbamoylpropanamido]-3-carboxypropanamido]-3-hydroxybutanoic acid

C16H27N5O10 (449.1758)


   

Thr Asn Glu Ser

(4S)-4-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-carbamoylpropanamido]-4-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Thr Asn Ser Glu

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-carbamoylpropanamido]-3-hydroxypropanamido]pentanedioic acid

C16H27N5O10 (449.1758)


   

Thr Asn Thr Asp

(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-carbamoylpropanamido]-3-hydroxybutanamido]butanedioic acid

C16H27N5O10 (449.1758)


   

Thr Gln Asp Ser

(3S)-3-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-carbamoylbutanamido]-3-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}propanoic acid

C16H27N5O10 (449.1758)


   

Thr Gln Ser Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-4-carbamoylbutanamido]-3-hydroxypropanamido]butanedioic acid

C16H27N5O10 (449.1758)


   

Thr Ser Asp Gln

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-hydroxypropanamido]-3-carboxypropanamido]-4-carbamoylbutanoic acid

C16H27N5O10 (449.1758)


   

Thr Ser Glu Asn

(4S)-4-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-hydroxypropanamido]-4-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}butanoic acid

C16H27N5O10 (449.1758)


   

Thr Ser Asn Glu

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-hydroxypropanamido]-3-carbamoylpropanamido]pentanedioic acid

C16H27N5O10 (449.1758)


   

Thr Ser Gln Asp

(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-hydroxypropanamido]-4-carbamoylbutanamido]butanedioic acid

C16H27N5O10 (449.1758)


   

Thr Thr Asp Asn

(3S)-3-[(2S,3R)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-hydroxybutanamido]-3-{[(1S)-2-carbamoyl-1-carboxyethyl]carbamoyl}propanoic acid

C16H27N5O10 (449.1758)


   

Thr Thr Asn Asp

(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-hydroxybutanamido]-3-carbamoylpropanamido]butanedioic acid

C16H27N5O10 (449.1758)


   

Trp Ala Ala Cys

(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]propanamido]propanamido]-3-sulfanylpropanoic acid

C20H27N5O5S (449.1733)


   

Trp Ala Cys Ala

(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]propanamido]-3-sulfanylpropanamido]propanoic acid

C20H27N5O5S (449.1733)


   

Trp Cys Ala Ala

(2S)-2-[(2S)-2-[(2R)-2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]-3-sulfanylpropanamido]propanamido]propanoic acid

C20H27N5O5S (449.1733)


   

Trp Gly Gly Met

(2S)-2-(2-{2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]acetamido}acetamido)-4-(methylsulfanyl)butanoic acid

C20H27N5O5S (449.1733)


   

Trp Gly Met Gly

2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]acetamido}-4-(methylsulfanyl)butanamido]acetic acid

C20H27N5O5S (449.1733)


   

Trp Met Gly Gly

2-{2-[(2S)-2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]-4-(methylsulfanyl)butanamido]acetamido}acetic acid

C20H27N5O5S (449.1733)


   

GTGES

Gly-Thr-Gly-Glu-Ser

C16H27N5O10 (449.1758)


   

Glisoxepid

N-{2-[4-({[(azepan-1-yl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-5-methyl-1,2-oxazole-3-carboxamide

C20H27N5O5S (449.1733)


A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BB - Sulfonylureas C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C97936 - Sulfonylurea Antidiabetic Agent

   

Sarmoxicillin

METHOXYMETHYL 7-[4-(4-HYDROXYPHENYL)-2,2-DIMETHYL-5-OXO-IMIDAZOLIDIN-1-YL]-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLATE

C21H27N3O6S (449.162)


D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams

   

hydrocodone bitartrate

hydrocodone bitartrate

C22H27NO9 (449.1686)


   

H-Arg-Gly-Asp-Cys-OH trifluoroacetate salt

H-Arg-Gly-Asp-Cys-OH trifluoroacetate salt

C15H27N7O7S (449.1693)


   

4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenyl-butyric acid

4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenyl-butyric acid

C27H28ClNO3 (449.1758)


   

Brexpiprazole S-oxide

Brexpiprazole S-oxide

C25H27N3O3S (449.1773)


   
   

Coelenterazine e

Coelenterazine e

C28H23N3O3 (449.1739)


   

N-[2,6-Bis(1-methylethyl)phenyl]-N-[4-[(4-nitrophenyl)thio]phenyl]urea

N-[2,6-Bis(1-methylethyl)phenyl]-N-[4-[(4-nitrophenyl)thio]phenyl]urea

C25H27N3O3S (449.1773)


VULM 1457 is a potent inhibitor of cholesterol acyltransferase (acyl-CoA). VULM1457 significantly reduces production and secretion of adrenomedullin (AM) and down-regulates AM receptors on human hepatoblastic cells. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM 1457 has the potential for the research of diabetes mellitus and hypercholesterolaemia[1][2].

   

N-(3,5-dimethylphenyl)-2-[[4-(4-fluorophenyl)-5-[(1-methyl-2-pyrrolyl)methyl]-1,2,4-triazol-3-yl]thio]acetamide

N-(3,5-dimethylphenyl)-2-[[4-(4-fluorophenyl)-5-[(1-methyl-2-pyrrolyl)methyl]-1,2,4-triazol-3-yl]thio]acetamide

C24H24FN5OS (449.1686)


   

1-{[(3R)-3-methyl-4-({4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]phenyl}sulfonyl)piperazin-1-yl]methyl}cyclopropanecarboxamide

1-{[(3R)-3-methyl-4-({4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]phenyl}sulfonyl)piperazin-1-yl]methyl}cyclopropanecarboxamide

C19H26F3N3O4S (449.1596)


   

N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide

N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide

C24H21F2N5O2 (449.1663)


   

N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamide

N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamide

C25H27N3O3S (449.1773)


   

N-[3-(3,5-dimethyl-1-pyrazolyl)-2-hydroxypropyl]-N-(4-methylphenyl)-2-naphthalenesulfonamide

N-[3-(3,5-dimethyl-1-pyrazolyl)-2-hydroxypropyl]-N-(4-methylphenyl)-2-naphthalenesulfonamide

C25H27N3O3S (449.1773)


   

(2S,3S,3aR,9bR)-7-(2-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(pyridin-4-ylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester

(2S,3S,3aR,9bR)-7-(2-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(pyridin-4-ylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester

C25H24FN3O4 (449.1751)


   

methyl (2S,3S,3aR,9bR)-1-[(3-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-7-pyridin-3-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylate

methyl (2S,3S,3aR,9bR)-1-[(3-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-7-pyridin-3-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylate

C25H24FN3O4 (449.1751)


   

methyl (1R,9S,10S,11S)-5-(4-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylate

methyl (1R,9S,10S,11S)-5-(4-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylate

C25H24FN3O4 (449.1751)


   

2-[(2R,5S,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

2-[(2R,5S,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

C21H27N3O6S (449.162)


   

2-[(2S,5S,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

2-[(2S,5S,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

C21H27N3O6S (449.162)


   

2-[(2S,5R,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

2-[(2S,5R,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

C21H27N3O6S (449.162)


   

methyl (1S,9R,10R,11R)-5-(4-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylate

methyl (1S,9R,10R,11R)-5-(4-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylate

C25H24FN3O4 (449.1751)


   

2-[(2S,5R,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

2-[(2S,5R,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

C21H27N3O6S (449.162)


   

2-[(2R,5R,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

2-[(2R,5R,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

C21H27N3O6S (449.162)


   

2-[(2S,5S,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

2-[(2S,5S,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

C21H27N3O6S (449.162)


   

2-[(2R,5R,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

2-[(2R,5R,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

C21H27N3O6S (449.162)


   

2-[(2R,5S,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

2-[(2R,5S,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide

C21H27N3O6S (449.162)


   

(2R,3R,3aS,9bS)-7-(2-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(pyridin-4-ylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester

(2R,3R,3aS,9bS)-7-(2-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(pyridin-4-ylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester

C25H24FN3O4 (449.1751)


   

(2R,3R,3aS,9bS)-1-[(3-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-7-(3-pyridinyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester

(2R,3R,3aS,9bS)-1-[(3-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-7-(3-pyridinyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester

C25H24FN3O4 (449.1751)


   
   
   
   
   
   
   
   
   
   
   
   
   

ST 20:5;O7;Gly

ST 20:5;O7;Gly

C22H27NO9 (449.1686)


   

OPC-14523 (hydrochloride)

OPC-14523 (hydrochloride)

C23H29Cl2N3O2 (449.1637)


OPC-14523 hydrochloride is an orally active sigma and 5-HT1A receptor agonist, with high affinity for sigma receptors (σ1/2 IC50=47/56 nM), the 5-HT1A receptor (IC50=2.3 nM), and the 5-HT transporter (IC50=80 nM). OPC-14523 hydrochloride shows antidepressant-like activity[1][2].

   

(2r,3r,4s,5s,6r)-2-{[(1s,17s,18s,19r)-17-hydroxy-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraen-18-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

(2r,3r,4s,5s,6r)-2-{[(1s,17s,18s,19r)-17-hydroxy-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraen-18-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

C22H27NO9 (449.1686)


   

2-({17-hydroxy-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraen-18-yl}oxy)-6-(hydroxymethyl)oxane-3,4,5-triol

2-({17-hydroxy-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraen-18-yl}oxy)-6-(hydroxymethyl)oxane-3,4,5-triol

C22H27NO9 (449.1686)


   

(2r,3s,4r,5s,6r)-2-{[(1r,17s,18s,19r)-17-hydroxy-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraen-18-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

(2r,3s,4r,5s,6r)-2-{[(1r,17s,18s,19r)-17-hydroxy-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraen-18-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol

C22H27NO9 (449.1686)


   

(7s)-5-chloro-3-[(5r,6r)-6-hydroxy-3,5-dimethylhepta-1,3-dien-1-yl]-2-(2-hydroxyethyl)-7-methyl-6,8-dioxoisoquinolin-7-yl acetate

(7s)-5-chloro-3-[(5r,6r)-6-hydroxy-3,5-dimethylhepta-1,3-dien-1-yl]-2-(2-hydroxyethyl)-7-methyl-6,8-dioxoisoquinolin-7-yl acetate

C23H28ClNO6 (449.1605)