Exact Mass: 449.166323
Exact Mass Matches: 449.166323
Found 313 metabolites which its exact mass value is equals to given mass value 449.166323
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Glisoxepide
C20H27N5O5S (449.1732812000001)
Glisoxepide is one of the sulphonamide-derived oral antidiabetic drugs. It inhibits the uptake of bile acids into isolated rat hepatocytes. However it inhibits taurocholate uptake only in the absence of sodium ions. Glisoxepide uptake could be further inhibited by blockers of the hepatocellular monocarboxylate transporter, by the loop diuretic bumetanide, by 4,4-diisothiocyano-2,2-stilbenedisulfonate (DIDS) and by sulphate. These results are consistent with the transport of glisoxepide via the transport system for the unconjugated bile acid cholate. (PMID:1618280, 9017793). A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BB - Sulfonylureas C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C97936 - Sulfonylurea Antidiabetic Agent
4-(tert-Butyl)-N-({[2-methyl-5-(morpholinosulfonyl)-3-furyl]carbonyl}oxy)benzenecarboximidamide
C21H27N3O6S (449.1620482000001)
4-[[4-[Hydroxy(4-methoxyphenyl)methyl]-5-[(4-hydroxyphenyl)methyl]-1-methyl-1H-imidazol-2-yl]amino]-1-methyl-1H-imidazole-2,5-dione
Ser Thr Asn Glu
C16H27N5O10 (449.17578419999995)
Ala Ala Cys Trp
C20H27N5O5S (449.1732812000001)
Ala Ala Trp Cys
C20H27N5O5S (449.1732812000001)
Ala Cys Ala Trp
C20H27N5O5S (449.1732812000001)
Ala Cys Glu Gln
Ala Cys Gln Glu
Ala Cys Trp Ala
C20H27N5O5S (449.1732812000001)
Ala Asp Met Asn
Ala Asp Asn Met
Ala Glu Cys Gln
Ala Glu Gln Cys
Ala Met Asp Asn
Ala Met Asn Asp
Ala Asn Asp Met
Ala Asn Met Asp
Ala Gln Cys Glu
Ala Gln Glu Cys
Ala Trp Ala Cys
C20H27N5O5S (449.1732812000001)
Ala Trp Cys Ala
C20H27N5O5S (449.1732812000001)
Cys Ala Ala Trp
C20H27N5O5S (449.1732812000001)
Cys Ala Glu Gln
Cys Ala Gln Glu
Cys Ala Trp Ala
C20H27N5O5S (449.1732812000001)
Cys Asp Gly Arg
Cys Asp Asn Val
Cys Asp Arg Gly
Cys Asp Val Asn
Cys Glu Ala Gln
Cys Glu Gln Ala
Cys Gly Asp Arg
Cys Gly Arg Asp
Cys Asn Asp Val
Cys Asn Val Asp
Cys Gln Ala Glu
Cys Gln Glu Ala
Cys Arg Asp Gly
Cys Arg Gly Asp
Cys Val Asp Asn
Cys Val Asn Asp
Cys Trp Ala Ala
C20H27N5O5S (449.1732812000001)
Asp Ala Met Asn
Asp Ala Asn Met
Asp Cys Gly Arg
Asp Cys Asn Val
Asp Cys Arg Gly
Asp Cys Val Asn
Asp Gly Cys Arg
Asp Gly Met Gln
Asp Gly Gln Met
Asp Gly Arg Cys
Asp Met Ala Asn
Asp Met Gly Gln
Asp Met Asn Ala
Asp Met Gln Gly
Asp Asn Ala Met
Asp Asn Cys Val
Asp Asn Met Ala
Asp Asn Thr Thr
C16H27N5O10 (449.17578419999995)
Asp Asn Val Cys
Asp Gln Gly Met
Asp Gln Met Gly
Asp Gln Ser Thr
C16H27N5O10 (449.17578419999995)
Asp Gln Thr Ser
C16H27N5O10 (449.17578419999995)
Asp Arg Cys Gly
Asp Arg Gly Cys
Asp Ser Gln Thr
C16H27N5O10 (449.17578419999995)
Asp Ser Thr Gln
C16H27N5O10 (449.17578419999995)
Asp Thr Asn Thr
C16H27N5O10 (449.17578419999995)
Asp Thr Gln Ser
C16H27N5O10 (449.17578419999995)
Asp Thr Ser Gln
C16H27N5O10 (449.17578419999995)
Asp Thr Thr Asn
C16H27N5O10 (449.17578419999995)
Asp Val Cys Asn
Asp Val Asn Cys
Glu Ala Cys Gln
Glu Ala Gln Cys
Glu Cys Ala Gln
Glu Cys Gln Ala
Glu Gly Met Asn
Glu Gly Asn Met
Glu Met Gly Asn
Glu Met Asn Gly
Glu Asn Gly Met
Glu Asn Met Gly
Glu Asn Ser Thr
C16H27N5O10 (449.17578419999995)
Glu Asn Thr Ser
C16H27N5O10 (449.17578419999995)
Glu Gln Ala Cys
Glu Gln Cys Ala
Glu Gln Ser Ser
C16H27N5O10 (449.17578419999995)
Glu Ser Asn Thr
C16H27N5O10 (449.17578419999995)
Glu Ser Gln Ser
C16H27N5O10 (449.17578419999995)
Glu Ser Ser Gln
C16H27N5O10 (449.17578419999995)
Glu Ser Thr Asn
C16H27N5O10 (449.17578419999995)
Glu Thr Asn Ser
C16H27N5O10 (449.17578419999995)
Glu Thr Ser Asn
C16H27N5O10 (449.17578419999995)
Gly Cys Asp Arg
Gly Cys Arg Asp
Gly Asp Cys Arg
Gly Asp Met Gln
Gly Asp Gln Met
Gly Asp Arg Cys
Gly Glu Met Asn
Gly Glu Asn Met
Gly Gly Met Trp
C20H27N5O5S (449.1732812000001)
Gly Gly Trp Met
C20H27N5O5S (449.1732812000001)
Gly Met Asp Gln
Gly Met Glu Asn
Gly Met Gly Trp
C20H27N5O5S (449.1732812000001)
Gly Met Asn Glu
Gly Met Gln Asp
Gly Met Trp Gly
C20H27N5O5S (449.1732812000001)
Gly Asn Glu Met
Gly Asn Met Glu
Gly Gln Asp Met
Gly Gln Met Asp
Gly Arg Cys Asp
Gly Arg Asp Cys
Gly Trp Gly Met
C20H27N5O5S (449.1732812000001)
Gly Trp Met Gly
C20H27N5O5S (449.1732812000001)
Met Ala Asp Asn
Met Ala Asn Asp
Met Asp Ala Asn
Met Asp Gly Gln
Met Asp Asn Ala
Met Asp Gln Gly
Met Glu Gly Asn
Met Glu Asn Gly
Met Gly Asp Gln
Met Gly Glu Asn
Met Gly Gly Trp
C20H27N5O5S (449.1732812000001)
Met Gly Asn Glu
Met Gly Gln Asp
Met Gly Trp Gly
C20H27N5O5S (449.1732812000001)
Met Asn Ala Asp
Met Asn Asp Ala
Met Asn Glu Gly
Met Asn Gly Glu
Met Gln Asp Gly
Met Gln Gly Asp
Met Trp Gly Gly
C20H27N5O5S (449.1732812000001)
Asn Ala Asp Met
Asn Ala Met Asp
Asn Cys Asp Val
Asn Cys Val Asp
Asn Asp Ala Met
Asn Asp Cys Val
Asn Asp Met Ala
Asn Asp Thr Thr
C16H27N5O10 (449.17578419999995)
Asn Asp Val Cys
Asn Glu Gly Met
Asn Glu Met Gly
Asn Glu Ser Thr
C16H27N5O10 (449.17578419999995)
Asn Glu Thr Ser
C16H27N5O10 (449.17578419999995)
Asn Gly Glu Met
Asn Gly Met Glu
Asn Met Ala Asp
Asn Met Asp Ala
Asn Met Glu Gly
Asn Met Gly Glu
Asn Ser Glu Thr
C16H27N5O10 (449.17578419999995)
Asn Ser Thr Glu
C16H27N5O10 (449.17578419999995)
Asn Thr Asp Thr
C16H27N5O10 (449.17578419999995)
Asn Thr Glu Ser
C16H27N5O10 (449.17578419999995)
Asn Thr Ser Glu
C16H27N5O10 (449.17578419999995)
Asn Thr Thr Asp
C16H27N5O10 (449.17578419999995)
Asn Val Cys Asp
Asn Val Asp Cys
Gln Ala Cys Glu
Gln Ala Glu Cys
Gln Cys Ala Glu
Gln Cys Glu Ala
Gln Asp Gly Met
Gln Asp Met Gly
Gln Asp Ser Thr
C16H27N5O10 (449.17578419999995)
Gln Asp Thr Ser
C16H27N5O10 (449.17578419999995)
Gln Glu Ala Cys
Gln Glu Cys Ala
Gln Glu Ser Ser
C16H27N5O10 (449.17578419999995)
Gln Gly Asp Met
Gln Gly Met Asp
Gln Met Asp Gly
Gln Met Gly Asp
Gln Ser Asp Thr
C16H27N5O10 (449.17578419999995)
Gln Ser Glu Ser
C16H27N5O10 (449.17578419999995)
Gln Ser Ser Glu
C16H27N5O10 (449.17578419999995)
Gln Ser Thr Asp
C16H27N5O10 (449.17578419999995)
Gln Thr Asp Ser
C16H27N5O10 (449.17578419999995)
Gln Thr Ser Asp
C16H27N5O10 (449.17578419999995)
Arg Cys Asp Gly
Arg Cys Gly Asp
Arg Asp Cys Gly
Arg Asp Gly Cys
Arg Gly Cys Asp
Arg Gly Asp Cys
Ser Asp Gln Thr
C16H27N5O10 (449.17578419999995)
Ser Asp Thr Gln
C16H27N5O10 (449.17578419999995)
Ser Glu Asn Thr
C16H27N5O10 (449.17578419999995)
Ser Glu Gln Ser
C16H27N5O10 (449.17578419999995)
Ser Glu Ser Gln
C16H27N5O10 (449.17578419999995)
Ser Glu Thr Asn
C16H27N5O10 (449.17578419999995)
Ser Asn Glu Thr
C16H27N5O10 (449.17578419999995)
Ser Asn Thr Glu
C16H27N5O10 (449.17578419999995)
Ser Gln Asp Thr
C16H27N5O10 (449.17578419999995)
Ser Gln Glu Ser
C16H27N5O10 (449.17578419999995)
Ser Gln Ser Glu
C16H27N5O10 (449.17578419999995)
Ser Gln Thr Asp
C16H27N5O10 (449.17578419999995)
Ser Ser Glu Gln
C16H27N5O10 (449.17578419999995)
Ser Ser Gln Glu
C16H27N5O10 (449.17578419999995)
Ser Thr Asp Gln
C16H27N5O10 (449.17578419999995)
Ser Thr Glu Asn
C16H27N5O10 (449.17578419999995)
Ser Thr Gln Asp
C16H27N5O10 (449.17578419999995)
Thr Asp Asn Thr
C16H27N5O10 (449.17578419999995)
Thr Asp Gln Ser
C16H27N5O10 (449.17578419999995)
Thr Asp Ser Gln
C16H27N5O10 (449.17578419999995)
Thr Asp Thr Asn
C16H27N5O10 (449.17578419999995)
Thr Glu Asn Ser
C16H27N5O10 (449.17578419999995)
Thr Glu Ser Asn
C16H27N5O10 (449.17578419999995)
Thr Asn Asp Thr
C16H27N5O10 (449.17578419999995)
Thr Asn Glu Ser
C16H27N5O10 (449.17578419999995)
Thr Asn Ser Glu
C16H27N5O10 (449.17578419999995)
Thr Asn Thr Asp
C16H27N5O10 (449.17578419999995)
Thr Gln Asp Ser
C16H27N5O10 (449.17578419999995)
Thr Gln Ser Asp
C16H27N5O10 (449.17578419999995)
Thr Ser Asp Gln
C16H27N5O10 (449.17578419999995)
Thr Ser Glu Asn
C16H27N5O10 (449.17578419999995)
Thr Ser Asn Glu
C16H27N5O10 (449.17578419999995)
Thr Ser Gln Asp
C16H27N5O10 (449.17578419999995)
Thr Thr Asp Asn
C16H27N5O10 (449.17578419999995)
Thr Thr Asn Asp
C16H27N5O10 (449.17578419999995)
Val Cys Asp Asn
Val Cys Asn Asp
Val Asp Cys Asn
Val Asp Asn Cys
Val Asn Cys Asp
Val Asn Asp Cys
Trp Ala Ala Cys
C20H27N5O5S (449.1732812000001)
Trp Ala Cys Ala
C20H27N5O5S (449.1732812000001)
Trp Cys Ala Ala
C20H27N5O5S (449.1732812000001)
Trp Gly Gly Met
C20H27N5O5S (449.1732812000001)
Trp Gly Met Gly
C20H27N5O5S (449.1732812000001)
Trp Met Gly Gly
C20H27N5O5S (449.1732812000001)
Glisoxepid
C20H27N5O5S (449.1732812000001)
A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BB - Sulfonylureas C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C97936 - Sulfonylurea Antidiabetic Agent
Sarmoxicillin
C21H27N3O6S (449.1620482000001)
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
Pyrrolo[1,2-a]pyrazine-3-acetic acid, 7-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]octahydro-1,4-dioxo-, (3S,7S,8aS)- (9CI)
4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenyl-butyric acid
C27H28ClNO3 (449.17576080000003)
B-spiro[9H-fluorene-9,8-indolo[3,2,1-de]acridin]-2-yl-Boronic acid
B-spiro[9H-Fluorene-9,8-indolo[3,2,1-de]acridin]-3-ylboronic acid
B-spiro[9H-Fluorene-9,8-indolo[3,2,1-de]acridin]-4-ylboronic acid
N-(3,5-dimethylphenyl)-2-[[4-(4-fluorophenyl)-5-[(1-methyl-2-pyrrolyl)methyl]-1,2,4-triazol-3-yl]thio]acetamide
1-{[(3R)-3-methyl-4-({4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]phenyl}sulfonyl)piperazin-1-yl]methyl}cyclopropanecarboxamide
C19H26F3N3O4S (449.15960320000005)
N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide
(2S,3S,3aR,9bR)-7-(2-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(pyridin-4-ylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester
methyl (2S,3S,3aR,9bR)-1-[(3-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-7-pyridin-3-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylate
methyl (1R,9S,10S,11S)-5-(4-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylate
2-[(2R,5S,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
C21H27N3O6S (449.1620482000001)
2-[(2S,5S,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
C21H27N3O6S (449.1620482000001)
2-[(2S,5R,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
C21H27N3O6S (449.1620482000001)
methyl (1S,9R,10R,11R)-5-(4-fluorophenyl)-10-(hydroxymethyl)-6-oxo-12-(pyridin-3-ylmethyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxylate
2-[(2S,5R,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
C21H27N3O6S (449.1620482000001)
2-[(2R,5R,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
C21H27N3O6S (449.1620482000001)
2-[(2S,5S,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
C21H27N3O6S (449.1620482000001)
2-[(2R,5R,6R)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
C21H27N3O6S (449.1620482000001)
2-[(2R,5S,6S)-6-(hydroxymethyl)-5-[(3-methoxyphenyl)sulfonylamino]-2-oxanyl]-N-(pyridin-4-ylmethyl)acetamide
C21H27N3O6S (449.1620482000001)
(2R,3R,3aS,9bS)-7-(2-fluorophenyl)-3-(hydroxymethyl)-6-oxo-1-(pyridin-4-ylmethyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester
(2R,3R,3aS,9bS)-1-[(3-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-7-(3-pyridinyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxylic acid methyl ester
OPC-14523 (hydrochloride)
OPC-14523 hydrochloride is an orally active sigma and 5-HT1A receptor agonist, with high affinity for sigma receptors (σ1/2 IC50=47/56 nM), the 5-HT1A receptor (IC50=2.3 nM), and the 5-HT transporter (IC50=80 nM). OPC-14523 hydrochloride shows antidepressant-like activity[1][2].
(2r,3r,4s,5s,6r)-2-{[(1s,17s,18s,19r)-17-hydroxy-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraen-18-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
2-({17-hydroxy-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraen-18-yl}oxy)-6-(hydroxymethyl)oxane-3,4,5-triol
(2r,3s,4r,5s,6r)-2-{[(1r,17s,18s,19r)-17-hydroxy-5,7-dioxa-12-azapentacyclo[10.6.1.0²,¹⁰.0⁴,⁸.0¹⁵,¹⁹]nonadeca-2,4(8),9,15-tetraen-18-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
(7s)-5-chloro-3-[(5r,6r)-6-hydroxy-3,5-dimethylhepta-1,3-dien-1-yl]-2-(2-hydroxyethyl)-7-methyl-6,8-dioxoisoquinolin-7-yl acetate
C23H28ClNO6 (449.16050580000007)