Exact Mass: 449.1637

Exact Mass Matches: 449.1637

Found 1 metabolites which its exact mass value is equals to given mass value 449.1637, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

OPC-14523 (hydrochloride)

OPC-14523 (hydrochloride)

C23H29Cl2N3O2 (449.1637)


OPC-14523 hydrochloride is an orally active sigma and 5-HT1A receptor agonist, with high affinity for sigma receptors (σ1/2 IC50=47/56 nM), the 5-HT1A receptor (IC50=2.3 nM), and the 5-HT transporter (IC50=80 nM). OPC-14523 hydrochloride shows antidepressant-like activity[1][2].