Exact Mass: 449.1637

Exact Mass Matches: 449.1637

Found 1 metabolites which its exact mass value is equals to given mass value 449.1637, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

OPC-14523 (hydrochloride)

OPC-14523 (hydrochloride)

C23H29Cl2N3O2 (449.1637)


OPC-14523 hydrochloride is an orally active sigma and 5-HT1A receptor agonist, with high affinity for sigma receptors (σ1/2 IC50=47/56 nM), the 5-HT1A receptor (IC50=2.3 nM), and the 5-HT transporter (IC50=80 nM). OPC-14523 hydrochloride shows antidepressant-like activity[1][2].