Exact Mass: 449.1273
Exact Mass Matches: 449.1273
Found 1 metabolites which its exact mass value is equals to given mass value 449.1273,
within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error
8.0E-6 dalton.
Brilaroxazine
C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent Brilaroxazine (RP5603) is a potent and orally active multimodal dopamine (DA)/serotonin (5-HT) modulator. Brilaroxazine is a partial agonist of dopamine (DA) D2, D3, and D4?receptors, 5-HT1A (Ki=1.5 nM)?and 5-HT2A (Ki=2.5 nM), and has antagonist activity at 5-HT2B (Ki=0.19 nM), and 5-HT7 (Ki=2.7 nM) receptors[1]. Brilaroxazine is an atypical antipsychotic agent, and has the potential to improve cognitive impairments in neuropsychiatric and neurological diseases in vivo[2].
