Exact Mass: 444.3022

Exact Mass Matches: 444.3022

Found 143 metabolites which its exact mass value is equals to given mass value 444.3022, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Menatetrenone

2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl]-1,4-dihydronaphthalene-1,4-dione

C31H40O2 (444.3028)

Menatetrenone, also known as MK-4, is a vitamin K compound used as a hemostatic agent, and also as adjunctive therapy for the pain of osteoporosis. Menatetrenone is one of the nine forms of vitamin K2 and is a short-chain menaquinone. MK-4 is produced via conversion of vitamin K1 in the body, in the testes, pancreas and arterial walls (Wikipedia). Vitamin K2 is found in brassicas. Vitamin K2 is widely distributed in green leaves and vegetables. It is a fat-soluble dietary factor effective in controlling blood coagulation. All members of the vitamin K group of vitamins share a methylated naphthoquinone ring structure and vary in the aliphatic side chain attached at the 3-position. Phylloquinone (also known as vitamin K1) invariably contains in its side chain four isoprenoid residues, one of which is unsaturated. Human milk contains between 1 and 4 micrograms/litre of vitamin K1, while formula-derived milk can contain up to 100 micrograms/litre in supplemented formulas. Vitamin K2 concentrations in human milk appear to be much lower than those of vitamin K1. It is estimated that there is a 0.25 to 1.7 percent occurrence of vitamin K deficiency bleeding in the first week of the infants life with a prevalence of 2-10 cases per 100,000 births. The biochemistry of how vitamin K is used to convert glutamic acid (Glu) to gamma-carboxyglutamic acid (Gla) has been elucidated over the past thirty years in academic laboratories throughout the world. Within the cell, vitamin K undergoes electron reduction to a reduced form of vitamin K (called vitamin K hydroquinone) by the enzyme vitamin K epoxide reductase (or VKOR). Another enzyme then oxidizes vitamin K hydroquinone to allow carboxylation of Glu to Gla; this enzyme is called the gamma-glutamyl carboxylase or the vitamin K-dependent carboxylase. The carboxylation reaction will only proceed if the carboxylase enzyme is able to oxidize vitamin K hydroquinone to vitamin K epoxide at the same time. The carboxylation and epoxidation reactions are said to be coupled reactions. Vitamin K epoxide is then re-converted into vitamin K by the vitamin K epoxide reductase. These two enzymes comprise the so-called vitamin K cycle. Vitamin K2 is one of the reasons why vitamin K is rarely deficient in a human diet (vitamin K is continually recycled in our cells). Vitamin K1 is also known as phylloquinone or phytomenadione (also called phytonadione). Vitamin K2 (menaquinone, menatetrenone) is normally produced by bacteria in the large intestine, and dietary deficiency is extremely rare unless the intestines are heavily damaged or are unable to absorb the molecule, or due to decreased production by normal flora, as seen in broad spectrum antibiotic use. Menaquinone-4 is a menaquinone whose side-chain contains 4 isoprene units in an all-trans-configuration. It has a role as a bone density conservation agent, a human metabolite, an antioxidant, an anti-inflammatory agent and a neuroprotective agent. Menatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State, and Hepatocellular Carcinoma. Menatetrenone is a menaquinone compound and form of vitamin K2 with potential antineoplastic activity. Menatetrenone may act by modulating the signalling of certain tyrosine kinases, thereby affecting several transcription factors including c-myc and c-fos. This agent inhibits tumor cell growth by inducing apoptosis and cell cycle arrest. M - Musculo-skeletal system > M05 - Drugs for treatment of bone diseases > M05B - Drugs affecting bone structure and mineralization Inhibits bone resorption via PGE2 synthesis inhibition and other mechanisms. Antihaemorrhagic vitamin [CCD] A menaquinone whose side-chain contains 4 isoprene units in an all-trans-configuration. D006401 - Hematologic Agents > D003029 - Coagulants > D006490 - Hemostatics Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

Stearyl citrate

2-hydroxy-2-[2-(octadecyloxy)-2-oxoethyl]butanedioic acid

C24H44O7 (444.3087)

Stearyl citrate is used as a food additive [EAFUS] ("EAFUS: Everything Added to Food in the United States. [http://www.eafus.com/]")

2-Stearyl citrate

3-hydroxy-3-[(octadecyloxy)carbonyl]pentanedioic acid

C24H44O7 (444.3087)

Antioxidant, sequestrant and emulsifier for use in margarine. Plasticiser for food contact packaging. Antioxidant, sequestrant and emulsifier for use in margarine. Plasticiser for food contact packaging

vitamin K2

2-methyl-3-(3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl)-1,4-dihydronaphthalene-1,4-dione

C31H40O2 (444.3028)

[(3S,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] octadec-9-enoate

[(3S,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] octadec-9-enoic acid

C24H44O7 (444.3087)

Triophaxanthin

C31H40O2 (444.3028)

12(R)-(beta-D-glucopyranosyloxy)octadecanoic acid 1,2-cyclic ester|gallicaside H

C24H44O7 (444.3087)

Ala Lys Lys Val

(2S)-2-[(2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]hexanamido]-3-methylbutanoic acid

C20H40N6O5 (444.306)

Ala Lys Val Lys

(2S)-6-amino-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-aminopropanamido]hexanamido]-3-methylbutanamido]hexanoic acid

C20H40N6O5 (444.306)

Ala Val Lys Lys

(2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylbutanamido]hexanamido]hexanoic acid

C20H40N6O5 (444.306)

Gly Ile Lys Lys

(2S)-6-amino-2-[(2S)-6-amino-2-[(2S,3S)-2-(2-aminoacetamido)-3-methylpentanamido]hexanamido]hexanoic acid

C20H40N6O5 (444.306)

Gly Lys Ile Lys

(2S)-6-amino-2-[(2S,3S)-2-[(2S)-6-amino-2-(2-aminoacetamido)hexanamido]-3-methylpentanamido]hexanoic acid

C20H40N6O5 (444.306)

Gly Lys Lys Ile

(2S,3S)-2-[(2S)-6-amino-2-[(2S)-6-amino-2-(2-aminoacetamido)hexanamido]hexanamido]-3-methylpentanoic acid

C20H40N6O5 (444.306)

Gly Lys Lys Leu

(2S)-2-[(2S)-6-amino-2-[(2S)-6-amino-2-(2-aminoacetamido)hexanamido]hexanamido]-4-methylpentanoic acid

C20H40N6O5 (444.306)

Gly Lys Leu Lys

(2S)-6-amino-2-[(2S)-2-[(2S)-6-amino-2-(2-aminoacetamido)hexanamido]-4-methylpentanamido]hexanoic acid

C20H40N6O5 (444.306)

Gly Leu Lys Lys

(2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-2-(2-aminoacetamido)-4-methylpentanamido]hexanamido]hexanoic acid

C20H40N6O5 (444.306)

Ile Gly Lys Lys

(2S)-6-amino-2-[(2S)-6-amino-2-{2-[(2S,3S)-2-amino-3-methylpentanamido]acetamido}hexanamido]hexanoic acid

C20H40N6O5 (444.306)

Ile Ile Ile Ser

(2S)-2-[(2S,3S)-2-[(2S,3S)-2-[(2S,3S)-2-amino-3-methylpentanamido]-3-methylpentanamido]-3-methylpentanamido]-3-hydroxypropanoic acid