Exact Mass: 444.1169

Exact Mass Matches: 444.1169

Found 2 metabolites which its exact mass value is equals to given mass value 444.1169, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

4-Hydroxyphenytoin glucuronide

(2S,3S,4S,5R)-6-[4-(2,5-dioxo-4-phenylimidazolidin-4-yl)phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid

C21H20N2O9 (444.1169)


4-Hydroxyphenytoin glucuronide is a metabolite of phenytoin. Phenytoin sodium is a commonly used antiepileptic. Phenytoin acts to suppress the abnormal brain activity seen in seizure by reducing electrical conductance among brain cells by stabilizing the inactive state of voltage-gated sodium channels. Aside from seizures, it is an option in the treatment of trigeminal neuralgia in the event that carbamazepine or other first-line treatment seems inappropriate. It is sometimes considered a class 1b antiarrhythmic. (Wikipedia)

   

p-Hydroxyphenytoin glucuronide

p-Hydroxyphenytoin glucuronide

C21H20N2O9 (444.1169)