Exact Mass: 442.1376092

Exact Mass Matches: 442.1376092

Found 12 metabolites which its exact mass value is equals to given mass value 442.1376092, within given mass tolerance error 8.0E-6 dalton. Try search metabolite list with more accurate mass tolerance error 1.6E-6 dalton.

12-Dehydrotetracycline

5a,11a-Dehydrotetracycline; 12-Dehydrotetracycline

C22H22N2O8 (442.1376092)


The 12-dehydro derivative of tetracycline.

   

Methacycline

(4S,4aR,5S,5aR,12aS)-4-(dimethylamino)-5,10,12,12a-tetrahydroxy-6-methylidene-1,3,11-trioxo-1,2,3,4,4a,5,5a,6,11,12a-decahydrotetracene-2-carboxamide

C22H22N2O8 (442.1376092)


Methacycline is only found in individuals that have used or taken this drug. It is a broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period. [PubChem]Methacycline, a tetracycline antibiotic, is a protein synthesis inhibitors, inhibiting the binding of aminoacyl-tRNA to the mRNA-ribosome complex. Methacycline inhibits cell growth by inhibiting translation. It binds to the 16S part of the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Tetracyclines also have been found to inhibit matrix metalloproteinases. This mechanism does not add to their antibiotic effects, but has led to extensive research on chemically modified tetracyclines or CMTs (like incyclinide) for the treatmet of rosacea, acne, and various types of neoplasms. J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01A - Tetracyclines > J01AA - Tetracyclines C784 - Protein Synthesis Inhibitor > C1595 - Tetracycline Antibiotic D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents C254 - Anti-Infective Agent > C258 - Antibiotic

   

Rondomycin

4-(Dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-3,4,4a,5,5a,6,12,12a-octahydrotetracene-2-carboximidate

C22H22N2O8 (442.1376092)


   

methacycline

methacycline

C22H22N2O8 (442.1376092)


J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01A - Tetracyclines > J01AA - Tetracyclines A tetracycline that is the 6-methylene analogue of oxytetracycline, obtained by formal dehydration at position 6. C784 - Protein Synthesis Inhibitor > C1595 - Tetracycline Antibiotic D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents C254 - Anti-Infective Agent > C258 - Antibiotic

   

alpha-apo-oxytetracycline

alpha-apo-oxytetracycline

C22H22N2O8 (442.1376092)


   

α-Apo-oxytetracycline

α-Apo-oxytetracycline

C22H22N2O8 (442.1376092)


   

Rondomycin

Rondomycin

C22H22N2O8 (442.1376092)


D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents

   

5a,11a-Dehydrotetracycline

5a,11a-Dehydrotetracycline

C22H22N2O8 (442.1376092)


   

(4S,4aR,5S,5aR,12aR)-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methylidene-1,3,12-trioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide

(4S,4aR,5S,5aR,12aR)-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methylidene-1,3,12-trioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide

C22H22N2O8 (442.1376092)


   

(4R,4aR,5R,5aR,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide

(4R,4aR,5R,5aR,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide

C22H22N2O8 (442.1376092)


   

12-dehydrotetracycline zwitterion

12-dehydrotetracycline zwitterion

C22H22N2O8 (442.1376092)


Zwitterionic form of 12-dehydrotetracycline arising from transfer of a proton from the 2-hydroxy group to the adjacent tertiary amino group.