Exact Mass: 442.1314
Exact Mass Matches: 442.1314
Found 88 metabolites which its exact mass value is equals to given mass value 442.1314,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
12-Dehydrotetracycline
5a,11a-Dehydrotetracycline; 12-Dehydrotetracycline
The 12-dehydro derivative of tetracycline.
Methacycline
(4S,4aR,5S,5aR,12aS)-4-(dimethylamino)-5,10,12,12a-tetrahydroxy-6-methylidene-1,3,11-trioxo-1,2,3,4,4a,5,5a,6,11,12a-decahydrotetracene-2-carboxamide
Methacycline is only found in individuals that have used or taken this drug. It is a broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period. [PubChem]Methacycline, a tetracycline antibiotic, is a protein synthesis inhibitors, inhibiting the binding of aminoacyl-tRNA to the mRNA-ribosome complex. Methacycline inhibits cell growth by inhibiting translation. It binds to the 16S part of the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Tetracyclines also have been found to inhibit matrix metalloproteinases. This mechanism does not add to their antibiotic effects, but has led to extensive research on chemically modified tetracyclines or CMTs (like incyclinide) for the treatmet of rosacea, acne, and various types of neoplasms. J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01A - Tetracyclines > J01AA - Tetracyclines C784 - Protein Synthesis Inhibitor > C1595 - Tetracycline Antibiotic D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents C254 - Anti-Infective Agent > C258 - Antibiotic
Rondomycin
4-(Dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-3,4,4a,5,5a,6,12,12a-octahydrotetracene-2-carboximidate
Pratensin A
(E)-5,7-Dihydroxy-3,6-dimethoxy-2-(4-methoxyphenyl)-4-oxo-4H-1-benzopyran-8-yl ester 2-methyl-2-butenoic acid
(+)-phrymarin II|1-acetoxy-2e-piperonyl-6e-[6-methoxypiperonyl]-3,7-dioxabicyclo[3.3.0]octane
(+)-phrymarin II|1-acetoxy-2e-piperonyl-6e-[6-methoxypiperonyl]-3,7-dioxabicyclo[3.3.0]octane
(-)-sanguinolignan C|(8S,7S,8R)-7-acetoxy-3,4-methylenedioxy-3,4-dimethoxy-7-oxolignano-9,9-lactone
(-)-sanguinolignan C|(8S,7S,8R)-7-acetoxy-3,4-methylenedioxy-3,4-dimethoxy-7-oxolignano-9,9-lactone
2,3-Dimethoxy-14,15-dihydroxy-16,16-dimethyl-9,10-(epoxypropano)-5,11,13-trioxa-5H-benzo[4,5]cyclohepta[1,2-b]naphthalene-6(12H)-one
2,3-Dimethoxy-14,15-dihydroxy-16,16-dimethyl-9,10-(epoxypropano)-5,11,13-trioxa-5H-benzo[4,5]cyclohepta[1,2-b]naphthalene-6(12H)-one
(-)-(1R*,2S*,3S*,4S*,5R*,6R*)-2-O-acetyl-4-O-benzoyl-1-benzoyloxymethyl-1,6-epoxycyclohexan-2,3,4,5-tetrol|2-acetylrotepoxide B
(-)-(1R*,2S*,3S*,4S*,5R*,6R*)-2-O-acetyl-4-O-benzoyl-1-benzoyloxymethyl-1,6-epoxycyclohexan-2,3,4,5-tetrol|2-acetylrotepoxide B
2-acetyl-3-[(E)-caffeoyl]-1-[(E)-p-coumaroyl]glycerol|Lasiocarpin B
2-acetyl-3-[(E)-caffeoyl]-1-[(E)-p-coumaroyl]glycerol|Lasiocarpin B
Ala Cys Cys Phe
(2S)-2-[(2R)-2-[(2R)-2-[(2S)-2-aminopropanamido]-3-sulfanylpropanamido]-3-sulfanylpropanamido]-3-phenylpropanoic acid
Ala Cys Phe Cys
(2R)-2-[(2S)-2-[(2R)-2-[(2S)-2-aminopropanamido]-3-sulfanylpropanamido]-3-phenylpropanamido]-3-sulfanylpropanoic acid
Ala Phe Cys Cys
(2R)-2-[(2R)-2-[(2S)-2-[(2S)-2-aminopropanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]-3-sulfanylpropanoic acid
Cys Ala Cys Phe
(2S)-2-[(2R)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]propanamido]-3-sulfanylpropanamido]-3-phenylpropanoic acid
Cys Ala Phe Cys
(2R)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]propanamido]-3-phenylpropanamido]-3-sulfanylpropanoic acid
Cys Cys Ala Phe
(2S)-2-[(2S)-2-[(2R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-sulfanylpropanamido]propanamido]-3-phenylpropanoic acid
Cys Cys Phe Ala
(2S)-2-[(2S)-2-[(2R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-sulfanylpropanamido]-3-phenylpropanamido]propanoic acid
Cys Phe Ala Cys
(2R)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-phenylpropanamido]propanamido]-3-sulfanylpropanoic acid
Cys Phe Cys Ala
(2S)-2-[(2R)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]propanoic acid
Mometasone Metabolite (Pregna-1,4-diene-3,20-dione, 9,21-dichloro-6,11,17-trihydroxy-16-methyl-, (6b
Mometasone Metabolite (Pregna-1,4-diene-3,20-dione, 9,21-dichloro-6,11,17-trihydroxy-16-methyl-, (6b
Mometasone Metabolite (Pregna-1,4-diene-3,20-dione, 9,21-dichloro-6,11,17-trihydroxy-16-methyl-, (6a
Mometasone Metabolite (Pregna-1,4-diene-3,20-dione, 9,21-dichloro-6,11,17-trihydroxy-16-methyl-, (6a
Phe Ala Cys Cys
(2R)-2-[(2R)-2-[(2S)-2-[(2S)-2-amino-3-phenylpropanamido]propanamido]-3-sulfanylpropanamido]-3-sulfanylpropanoic acid
Phe Cys Ala Cys
(2R)-2-[(2S)-2-[(2R)-2-[(2S)-2-amino-3-phenylpropanamido]-3-sulfanylpropanamido]propanamido]-3-sulfanylpropanoic acid
Phe Cys Cys Ala
(2S)-2-[(2R)-2-[(2R)-2-[(2S)-2-amino-3-phenylpropanamido]-3-sulfanylpropanamido]-3-sulfanylpropanamido]propanoic acid
methacycline
methacycline
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01A - Tetracyclines > J01AA - Tetracyclines A tetracycline that is the 6-methylene analogue of oxytetracycline, obtained by formal dehydration at position 6. C784 - Protein Synthesis Inhibitor > C1595 - Tetracycline Antibiotic D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents C254 - Anti-Infective Agent > C258 - Antibiotic
(1S,2S)-1,2-Bis(4-dimethylaminophenyl)-1,2-ethanediamine tetrahydrochloride
(1S,2S)-1,2-Bis(4-dimethylaminophenyl)-1,2-ethanediamine tetrahydrochloride
Methyl 2-oxo-3-{[2-(5-oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)-4-biphenylyl]methyl}-2,3-dihydro-1H-benzimidazole-4-carboxylate
Methyl 2-oxo-3-{[2-(5-oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)-4-biphenylyl]methyl}-2,3-dihydro-1H-benzimidazole-4-carboxylate
(4S,4aR,5S,5aR,12aR)-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methylidene-1,3,12-trioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
(4S,4aR,5S,5aR,12aR)-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methylidene-1,3,12-trioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
(-)-sanguinolignan C
(-)-sanguinolignan C
A lignan isolated from the leaves of Piper sanguineispicum.
4-methyl-N-(2-phenylphenyl)-3-(phenylsulfamoyl)benzamide
4-methyl-N-(2-phenylphenyl)-3-(phenylsulfamoyl)benzamide
2-[[2-[4-(4-Chlorophenyl)-1-piperazinyl]-2-oxoethyl]thio]-3-ethyl-4-quinazolinone
2-[[2-[4-(4-Chlorophenyl)-1-piperazinyl]-2-oxoethyl]thio]-3-ethyl-4-quinazolinone
3-[[[[3-[(4-Chlorophenyl)methyl]-2-methyl-4-oxo-6-quinazolinyl]amino]-oxomethyl]amino]propanoic acid ethyl ester
3-[[[[3-[(4-Chlorophenyl)methyl]-2-methyl-4-oxo-6-quinazolinyl]amino]-oxomethyl]amino]propanoic acid ethyl ester
[5-(2-Furanyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone
[5-(2-Furanyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]-[4-(2-pyridinyl)-1-piperazinyl]methanone
methyl (1S,3R)-2-(chloroacetyl)-1-[4-(methoxycarbonyl)phenyl]-2,3,4,4a,9,9a-hexahydro-1H-beta-carboline-3-carboxylate
methyl (1S,3R)-2-(chloroacetyl)-1-[4-(methoxycarbonyl)phenyl]-2,3,4,4a,9,9a-hexahydro-1H-beta-carboline-3-carboxylate
2-[2-(2,5-difluoroanilino)-2-hydroxyethyl]sulfanyl-3-ethyl-7-phenyl-5H-pyrrolo[3,2-d]pyrimidin-4-one
2-[2-(2,5-difluoroanilino)-2-hydroxyethyl]sulfanyl-3-ethyl-7-phenyl-5H-pyrrolo[3,2-d]pyrimidin-4-one
3-[(4aS,12aR)-2-methyl-1,3,4,5,12,12a-hexahydropyrido[3,4-b]acridin-4a-yl]phenol;hydrate;hydrobromide
3-[(4aS,12aR)-2-methyl-1,3,4,5,12,12a-hexahydropyrido[3,4-b]acridin-4a-yl]phenol;hydrate;hydrobromide
15-(1,3-Dihydroxy-3-methylbutyl)-4,18-dihydroxy-2-methoxy-7,9,13-trioxapentacyclo[10.8.0.03,10.04,8.014,19]icosa-1,3(10),5,11,14,16,18-heptaen-20-one
15-(1,3-Dihydroxy-3-methylbutyl)-4,18-dihydroxy-2-methoxy-7,9,13-trioxapentacyclo[10.8.0.03,10.04,8.014,19]icosa-1,3(10),5,11,14,16,18-heptaen-20-one
(4R,4aR,5R,5aR,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
(4R,4aR,5R,5aR,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
S-adenosyl-S-carboxymethyl-L-homocysteine dizwitterion
S-adenosyl-S-carboxymethyl-L-homocysteine dizwitterion
A sulfonium betaine obtained by deprotonation of the carboxy groups and protonation of the amino group of S-adenosyl-S-carboxymethyl-L-homocysteine. Major microspecies at pH 7.3
12-dehydrotetracycline zwitterion
12-dehydrotetracycline zwitterion
Zwitterionic form of 12-dehydrotetracycline arising from transfer of a proton from the 2-hydroxy group to the adjacent tertiary amino group.
PF-739
PF-739
PF-739 is an orally active and non-selective activator of AMPK. PF-739 activates 12 heterotrimeric AMPK complexes and significantly reduces the level of glucose in plasma complexes[1][2].
5,7-dihydroxy-3,6-dimethoxy-2-(4-methoxyphenyl)-4-oxochromen-8-yl 2-methylbut-2-enoate
5,7-dihydroxy-3,6-dimethoxy-2-(4-methoxyphenyl)-4-oxochromen-8-yl 2-methylbut-2-enoate
2-amino-4-[(1-carboxy-2-{[3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-en-1-yl]sulfanyl}ethyl)-c-hydroxycarbonimidoyl]butanoic acid
2-amino-4-[(1-carboxy-2-{[3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-en-1-yl]sulfanyl}ethyl)-c-hydroxycarbonimidoyl]butanoic acid
4-[(10r,11r,15r,16r)-16-hydroxy-12-oxo-4,6,13-trioxatetracyclo[7.7.0.0³,⁷.0¹¹,¹⁵]hexadeca-1,3(7),8-trien-10-yl]-2,6-dimethoxyphenyl acetate
4-[(10r,11r,15r,16r)-16-hydroxy-12-oxo-4,6,13-trioxatetracyclo[7.7.0.0³,⁷.0¹¹,¹⁵]hexadeca-1,3(7),8-trien-10-yl]-2,6-dimethoxyphenyl acetate
2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-8-methoxy-4-oxochromen-3-yl 2-methylbut-2-enoate
2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-8-methoxy-4-oxochromen-3-yl 2-methylbut-2-enoate
methyl (1s,2s,4r)-2,4,5,7,12-pentahydroxy-6,11-dioxo-2-propyl-3,4-dihydro-1h-tetracene-1-carboxylate
methyl (1s,2s,4r)-2,4,5,7,12-pentahydroxy-6,11-dioxo-2-propyl-3,4-dihydro-1h-tetracene-1-carboxylate
3-(acetyloxy)-2-[4-(acetyloxy)phenyl]-5-methoxy-6-methyl-4-oxo-2,3-dihydro-1-benzopyran-7-yl acetate
3-(acetyloxy)-2-[4-(acetyloxy)phenyl]-5-methoxy-6-methyl-4-oxo-2,3-dihydro-1-benzopyran-7-yl acetate
[(2r,3r)-3-(3,4-dimethoxyphenyl)-5-methoxy-9-oxo-2h,3h-[1,4]dioxino[2,3-h]chromen-2-yl]methyl acetate
[(2r,3r)-3-(3,4-dimethoxyphenyl)-5-methoxy-9-oxo-2h,3h-[1,4]dioxino[2,3-h]chromen-2-yl]methyl acetate
[3-(3,4-dimethoxyphenyl)-5-methoxy-9-oxo-2h,3h-[1,4]dioxino[2,3-h]chromen-2-yl]methyl acetate
[3-(3,4-dimethoxyphenyl)-5-methoxy-9-oxo-2h,3h-[1,4]dioxino[2,3-h]chromen-2-yl]methyl acetate
(1s,6r,13r,21s)-10,13,21-trihydroxy-16,17-dimethoxy-6-(prop-1-en-2-yl)-2,7,20-trioxapentacyclo[11.8.0.0³,¹¹.0⁴,⁸.0¹⁴,¹⁹]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one
(1s,6r,13r,21s)-10,13,21-trihydroxy-16,17-dimethoxy-6-(prop-1-en-2-yl)-2,7,20-trioxapentacyclo[11.8.0.0³,¹¹.0⁴,⁸.0¹⁴,¹⁹]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one
1,4-dimethyl 2-(2h-1,3-benzodioxol-5-ylmethylidene)-3-[(7-methoxy-2h-1,3-benzodioxol-5-yl)methyl]butanedioate
1,4-dimethyl 2-(2h-1,3-benzodioxol-5-ylmethylidene)-3-[(7-methoxy-2h-1,3-benzodioxol-5-yl)methyl]butanedioate
(1s,2s,3s,4s,5r,6s)-5-(acetyloxy)-6-[(benzoyloxy)methyl]-2,4-dihydroxy-7-oxabicyclo[4.1.0]heptan-3-yl benzoate
(1s,2s,3s,4s,5r,6s)-5-(acetyloxy)-6-[(benzoyloxy)methyl]-2,4-dihydroxy-7-oxabicyclo[4.1.0]heptan-3-yl benzoate
3-hydroxy-2-{[hydroxy(4-hydroxy-1-methyl-2-oxopteridin-6-yl)methylidene]amino}-n-[2-(methoxycarbonyl)phenyl]propanimidic acid
3-hydroxy-2-{[hydroxy(4-hydroxy-1-methyl-2-oxopteridin-6-yl)methylidene]amino}-n-[2-(methoxycarbonyl)phenyl]propanimidic acid
(2s)-2-amino-4-{[(1r)-1-carboxy-2-{[(2e)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-en-1-yl]sulfanyl}ethyl]-c-hydroxycarbonimidoyl}butanoic acid
(2s)-2-amino-4-{[(1r)-1-carboxy-2-{[(2e)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-en-1-yl]sulfanyl}ethyl]-c-hydroxycarbonimidoyl}butanoic acid
1,4-dimethyl (2z)-2-(2h-1,3-benzodioxol-5-ylmethylidene)-3-[(7-methoxy-2h-1,3-benzodioxol-5-yl)methyl]butanedioate
1,4-dimethyl (2z)-2-(2h-1,3-benzodioxol-5-ylmethylidene)-3-[(7-methoxy-2h-1,3-benzodioxol-5-yl)methyl]butanedioate
1,4-dimethyl (2z,3s)-2-(2h-1,3-benzodioxol-5-ylmethylidene)-3-[(7-methoxy-2h-1,3-benzodioxol-5-yl)methyl]butanedioate
1,4-dimethyl (2z,3s)-2-(2h-1,3-benzodioxol-5-ylmethylidene)-3-[(7-methoxy-2h-1,3-benzodioxol-5-yl)methyl]butanedioate
10,13,21-trihydroxy-16,17-dimethoxy-6-(prop-1-en-2-yl)-2,7,20-trioxapentacyclo[11.8.0.0³,¹¹.0⁴,⁸.0¹⁴,¹⁹]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one
10,13,21-trihydroxy-16,17-dimethoxy-6-(prop-1-en-2-yl)-2,7,20-trioxapentacyclo[11.8.0.0³,¹¹.0⁴,⁸.0¹⁴,¹⁹]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one
(11r,15r,17r)-17-ethyl-2-hydroxy-5-[(2r,4r,6r)-4-hydroxy-6-methyl-5-oxooxan-2-yl]-12,16-dioxatetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadeca-1,3(8),5,9-tetraene-4,7,13-trione
(11r,15r,17r)-17-ethyl-2-hydroxy-5-[(2r,4r,6r)-4-hydroxy-6-methyl-5-oxooxan-2-yl]-12,16-dioxatetracyclo[8.7.0.0³,⁸.0¹¹,¹⁵]heptadeca-1,3(8),5,9-tetraene-4,7,13-trione
2-(acetyloxy)-3-{[3-(4-hydroxyphenyl)prop-2-enoyl]oxy}propyl 3-(3,4-dihydroxyphenyl)prop-2-enoate
2-(acetyloxy)-3-{[3-(4-hydroxyphenyl)prop-2-enoyl]oxy}propyl 3-(3,4-dihydroxyphenyl)prop-2-enoate
(2r)-2-(acetyloxy)-3-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}propyl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate
(2r)-2-(acetyloxy)-3-{[(2e)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy}propyl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate
(2s)-3-hydroxy-2-{[hydroxy(4-hydroxy-1-methyl-2-oxopteridin-6-yl)methylidene]amino}-n-[2-(methoxycarbonyl)phenyl]propanimidic acid
(2s)-3-hydroxy-2-{[hydroxy(4-hydroxy-1-methyl-2-oxopteridin-6-yl)methylidene]amino}-n-[2-(methoxycarbonyl)phenyl]propanimidic acid
methyl 2,4,5,7,12-pentahydroxy-6,11-dioxo-2-propyl-3,4-dihydro-1h-tetracene-1-carboxylate
methyl 2,4,5,7,12-pentahydroxy-6,11-dioxo-2-propyl-3,4-dihydro-1h-tetracene-1-carboxylate
(2s,3s)-3-(acetyloxy)-2-[4-(acetyloxy)phenyl]-5-methoxy-6-methyl-4-oxo-2,3-dihydro-1-benzopyran-7-yl acetate
(2s,3s)-3-(acetyloxy)-2-[4-(acetyloxy)phenyl]-5-methoxy-6-methyl-4-oxo-2,3-dihydro-1-benzopyran-7-yl acetate
[4-(2h-1,3-benzodioxole-5-carbonyl)-5-oxooxolan-3-yl](3,4-dimethoxyphenyl)methyl acetate
[4-(2h-1,3-benzodioxole-5-carbonyl)-5-oxooxolan-3-yl](3,4-dimethoxyphenyl)methyl acetate
