Exact Mass: 440.1488
Exact Mass Matches: 440.1488
Found 154 metabolites which its exact mass value is equals to given mass value 440.1488
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Aminopterin
Aminopterin Syndrome Sine Aminopterin (ASSA, OMIM 600325) is an embryopathy caused by maternal treatment with the olic acid antagonist aminopterin has been recognized since 1952 when aminopterin was used as an abortifacient. The characteristic phenotype of the children who survived infancy after having been exposed to aminopterin or its methyl derivative, methotrexate, in early pregnancy included a very unusual facies, skull anomalies, and skeletal defects.(OMIM). Aminopterin is an antimetabolite drug used in treatment of cancer and autoimmune diseases. It acts by inhibiting the metabolism of folic acid. - Wikipedia. The effects of the drug on intracellular metabolic processes, due to the inhibitory action on the enzyme dihydrofolate reductase, show that the result of this inhibition is more complex and is not limited to blockade of the reduction of folic acid alone. Although rescue methods are important in prevention of lethal effects of methotrexate, some metabolic pathways are insufficiently rescued, resulting in toxic reactions following methotrexate administration.(PMID 6398629). Aminopterin Syndrome Sine Aminopterin (ASSA, OMIM 600325) is an embryopathy caused by maternal treatment with the olic acid antagonist aminopterin has been recognized since 1952 when aminopterin was used as an abortifacient. The characteristic phenotype of the children who survived infancy after having been exposed to aminopterin or its methyl derivative, methotrexate, in early pregnancy included a very unusual facies, skull anomalies, and skeletal defects.(OMIM);
Propylene glycol alginate
Propylene glycol alginate is a stabiliser, emulsifier, thickener, formulation aid, surface active agent and flavouring adjunct or adjuvant for foodstuffs Propylene glycol alginate (PGA) is an emulsifier, stabilizer, and thickener used in food products. It is a food additive with E number E405. Chemically, propylene glycol alginate is an ester of alginic acid, which is derived from kelp. Some of the carboxyl groups are esterified with propylene glycol, some are neutralized with an appropriate alkali, and some remain free. Stabiliser, emulsifier, thickener, formulation aid, surface active agent and flavouring adjunct or adjuvant for foodstuffs
Azobilirubin
Butyrolactone derivative
9,11-Dihydroxy-2,3,6-trimethoxy-8-prenhyl-6a,12a-didehydrorotenone
3,5,8-Trimethoxy-3,4-methylenedioxy-7-prenyloxyflavone
3,5,8-Tri-Me,3,4-methylene ether,7-O-(3-methyl-2-butenyl)-Gossypetin
(2E)-3,4-dimethoxycinnamyl 3-(3,4-diacetoxyphenyl)acrylate
19,20-alpha-epoxy-12,15-dihydroxy-11-methoxyicajine
5,7,5-trimethoxy-6-(3-hydroxy-3-methyl-trans-but-1-enyl)-3,4-methylenedioxy flavone
O4-[O4,O6-((Xi)-1-Carboxy-aethyliden)-beta-D-galactopyranosyl]-3,6-anhydro-L-galactose-dimethylacetal|O4-[O4,O6-((Xi)-1-carboxy-ethylidene)-beta-D-galactopyranosyl]-3,6-anhydro-L-galactose-dimethylacetal
JGB1741
JGB1741 (ILS-JGB-1741) is a potent and specific SIRT1 activity inhibitor with an IC50 of ~15 μM. JGB1741 is a weak SIRT2 and SIRT3 inhibitor with an all IC50>100 μM. JGB1741 increases the acetylated p53 levels leading to p53-mediated apoptosis with modulation of Bax/Bcl2 ratio, cytochrome c release and PARP cleavage. JGB1741 has the potential for breast cancer research[1].
(E)-3-[1-[(E)-but-2-en-2-yl]-9-hydroxy-10-(hydroxymethyl)-3-methoxy-4-methyl-6-oxobenzo[b][1,4]benzodioxepin-7-yl]but-2-enoic acid
methyl 2-[[3-[(3,3-dimethyloxiran-2-yl)methyl]-4-hydroxyphenyl]methyl]-4-hydroxy-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylate
Aminopterin
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite C471 - Enzyme Inhibitor > C2153 - Dihydrofolate Reductase Inhibitor D004791 - Enzyme Inhibitors > D005493 - Folic Acid Antagonists
methyl 2-[[3-[(3,3-dimethyloxiran-2-yl)methyl]-4-hydroxyphenyl]methyl]-4-hydroxy-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylate
(E)-3-[1-[(E)-but-2-en-2-yl]-9-hydroxy-10-(hydroxymethyl)-3-methoxy-4-methyl-6-oxobenzo[b][1,4]benzodioxepin-7-yl]but-2-enoic acid [IIN-based on: CCMSLIB00000845225]
(E)-3-[1-[(E)-but-2-en-2-yl]-9-hydroxy-10-(hydroxymethyl)-3-methoxy-4-methyl-6-oxobenzo[b][1,4]benzodioxepin-7-yl]but-2-enoic acid [IIN-based: Match]
methyl 2-[[3-[(3,3-dimethyloxiran-2-yl)methyl]-4-hydroxyphenyl]methyl]-4-hydroxy-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylate [IIN-based on: CCMSLIB00000846943]
methyl 2-[[3-[(3,3-dimethyloxiran-2-yl)methyl]-4-hydroxyphenyl]methyl]-4-hydroxy-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylate [IIN-based: Match]
methyl 2-[[3-[(3,3-dimethyloxiran-2-yl)methyl]-4-hydroxyphenyl]methyl]-4-hydroxy-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylate [IIN-based on: CCMSLIB00000846940]
(E)-3-[1-[(E)-but-2-en-2-yl]-9-hydroxy-10-(hydroxymethyl)-3-methoxy-4-methyl-6-oxobenzo[b][1,4]benzodioxepin-7-yl]but-2-enoic acid [IIN-based on: CCMSLIB00000845223]
methyl 2-[[3-[(3,3-dimethyloxiran-2-yl)methyl]-4-hydroxyphenyl]methyl]-4-hydroxy-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylate_major
Cys Met Ser Thr
Cys Met Thr Ser
Cys Ser Met Thr
Cys Ser Thr Met
Cys Thr Met Ser
Cys Thr Ser Met
Asp Gly Ser Tyr
Asp Gly Tyr Ser
Asp Ser Gly Tyr
Asp Ser Tyr Gly
Asp Tyr Gly Ser
Asp Tyr Ser Gly
Gly Asp Ser Tyr
Gly Asp Tyr Ser
Gly Ser Asp Tyr
Gly Ser Tyr Asp
Gly Tyr Asp Ser
Gly Tyr Ser Asp
Met Cys Ser Thr
Met Cys Thr Ser
Met Ser Cys Thr
Met Ser Thr Cys
Met Thr Cys Ser
Met Thr Ser Cys
Ser Cys Met Thr
Ser Cys Thr Met
Ser Asp Gly Tyr
Ser Asp Tyr Gly
Ser Gly Asp Tyr
Ser Gly Tyr Asp
Ser Met Cys Thr
Ser Met Thr Cys
Ser Thr Cys Met
Ser Thr Met Cys
Ser Tyr Asp Gly
Ser Tyr Gly Asp
Thr Cys Met Ser
Thr Cys Ser Met
Thr Met Cys Ser
Thr Met Ser Cys
Thr Ser Cys Met
Thr Ser Met Cys
Tyr Asp Gly Ser
Tyr Asp Ser Gly
Tyr Gly Asp Ser
Tyr Gly Ser Asp
Tyr Ser Asp Gly
Tyr Ser Gly Asp
(4-CHLOROBENZYL)TRIPHEYLPHOSPHONIUM TETRAFLUOROBORATE
4-[[4-(aminocarbonyl)phenyl]azo]-3-hydroxy-N-(2-methoxyphenyl)naphthalene-2-carboxamide
2-((4-METHOXYPHENYL)AMINO)-1-(2-(TRIFLUOROMETHYL)BENZYL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXAMIDE
1,4-bis(4-phenylphenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-3,6-dione
3-hydroxy-4-[(2-methyl-5-nitrophenyl)azo]-N-(o-tolyl)naphthalene-2-carboxamide
1-METHYL-3-TRIFLUOROMETHYL-5-TRIBUTYLSTANNYLPYRAZOLE
4-Thiazolidinecarboxylic acid, 3-[[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]acetyl]-2,2-dimethyl-, (4R)-
(4Z)-4-[(5-carbamoyl-2-methoxyphenyl)hydrazinylidene]-3-oxo-N-phenylnaphthalene-2-carboxamide
(4Z)-4-[[2-methoxy-5-(phenylcarbamoyl)phenyl]hydrazinylidene]-3-oxonaphthalene-2-carboxamide
2-[[(3,4-dimethoxyphenyl)-oxomethyl]amino]-N-(2-furanylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
4-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-3-propyl-1H-pyrrol-2-yl]diazenyl]benzenesulfonic acid
6-[[4-(3,4-dihydro-2H-quinolin-1-ylsulfonyl)anilino]-oxomethyl]-1-cyclohex-3-enecarboxylic acid
4,5-Dimethoxy-2-[[1-oxo-2-[(3,5,8-trimethyl-2-quinolinyl)thio]ethyl]amino]benzoic acid
2-[N-(benzenesulfonyl)-4-ethoxyanilino]-N-(2-methoxyphenyl)acetamide
JP1302 dihydrochloride
JP1302 dihydrochloride is a potent, selective, high affinity antagonist of the α2C-adrenoceptor, with a Kb of 16 nM and a Ki of 28 nM for the human α2C-receptor. JP1302 dihydrochloride shows antidepressant and antipsychotic-like effects. JP1302 dihydrochloride can be used for neuropsychiatric disorders and renal dysfunction research[1][2][3].