Exact Mass: 436.3427
Exact Mass Matches: 436.3427
Found 63 metabolites which its exact mass value is equals to given mass value 436.3427,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Demethylphylloquinone
Demethylphylloquinone is a form of vitamin K that occurs in nature as part of a series of compounds with a common 2-methyl-1,4 naphthoquinone nucleus and differing isoprenoid side chains at the 3 position. Vitamin K forms comprise a single major plant form, phylloquinone with a phytyl side chain and a family of bacterially synthesized menaquinones (MKs) with multiprenyl side chains. Bacterially produced menaquinones are biologically active forms of vitamin K that are present in high concentrations in the human lower bowel. Both phylloquinone and menaquinones are bioactive in hepatic gamma-carboxylation but long-chain MKs are less well absorbed. Liver stores of vitamin K are relatively small. The hepatic reserves of phylloquinone (approximately 10\\% of the total) are labile and turn over at a faster rate than menaquinones. Vitamin K is recognised as a factor required for normal blood coagulation, and in relation to its role in bone metabolism. Vitamin K is a substrate for a liver microsomal enzyme that catalyzes the conversion of specific glutamyl residues to gamma-carboxyglutamyl residues in a limited number of proteins. These include the vitamin K-dependent clotting factors: prothrombin (factor II), factor VII, factor IX, and factor X. In the absence of vitamin K, nonfunctional clotting factors are synthesized and hemorrhage can result. Vitamin K is a coenzyme for glutamate carboxylase, which mediates the conversion of glutamate to gamma-carboxyglutamate (Gla). There are at least three Gla proteins associated with bone tissue, of which osteocalcin is the most abundant and best known. Trabecular and cortical bone appear to contain substantial concentrations of both phylloquinone and menaquinones. (PMID: 8642453, 8527227, 15018483, 1573141) [HMDB] Demethylphylloquinone is a form of vitamin K that occurs in nature as part of a series of compounds with a common 2-methyl-1,4 naphthoquinone nucleus and differing isoprenoid side chains at the 3 position. Vitamin K forms comprise a single major plant form, phylloquinone with a phytyl side chain and a family of bacterially synthesized menaquinones (MKs) with multiprenyl side chains. Bacterially produced menaquinones are biologically active forms of vitamin K that are present in high concentrations in the human lower bowel. Both phylloquinone and menaquinones are bioactive in hepatic gamma-carboxylation but long-chain MKs are less well absorbed. Liver stores of vitamin K are relatively small. The hepatic reserves of phylloquinone (approximately 10\\% of the total) are labile and turn over at a faster rate than menaquinones. Vitamin K is recognised as a factor required for normal blood coagulation, and in relation to its role in bone metabolism. Vitamin K is a substrate for a liver microsomal enzyme that catalyzes the conversion of specific glutamyl residues to gamma-carboxyglutamyl residues in a limited number of proteins. These include the vitamin K-dependent clotting factors: prothrombin (factor II), factor VII, factor IX, and factor X. In the absence of vitamin K, nonfunctional clotting factors are synthesized and hemorrhage can result. Vitamin K is a coenzyme for glutamate carboxylase, which mediates the conversion of glutamate to gamma-carboxyglutamate (Gla). There are at least three Gla proteins associated with bone tissue, of which osteocalcin is the most abundant and best known. Trabecular and cortical bone appear to contain substantial concentrations of both phylloquinone and menaquinones. (PMID: 8642453, 8527227, 15018483, 1573141).
Ganoderal A
Ganoderal A is found in mushrooms. Ganoderal A is a constituent of Ganoderma lucidum (reishi) Constituent of Ganoderma lucidum (reishi). Ganoderal A is found in mushrooms. Ganoderal A, an oxygenated sterol from G. lucidum, is a cholesterol synthesis inhibitor[1]. Ganoderal A, an oxygenated sterol from G. lucidum, is a cholesterol synthesis inhibitor[1].
Manglupenone
Manglupenone is found in fruits. Manglupenone is a constituent of the stem bark of Mangifera indica var. Dusehri Constituent of the stem bark of Mangifera indica variety Dusehri. Manglupenone is found in fruits.
ganoderal A
Ganoderal A is a triterpenoid. ganoderal A is a natural product found in Ganoderma pfeifferi, Ganoderma, and Ganoderma lucidum with data available. Ganoderal A, an oxygenated sterol from G. lucidum, is a cholesterol synthesis inhibitor[1]. Ganoderal A, an oxygenated sterol from G. lucidum, is a cholesterol synthesis inhibitor[1].
7beta-(1S,5-dimethyl-4-hexenyl)-3aalpha,4,4aalpha,5,6,7,8,8a,9,9aalpha-decahydro-5,8abeta-dimethyl-5-methylenspiro(bicyclo[2.2.2]oct-5-en-2,3(2H)-naphtho[2,3-b]furan)-2-on|7beta-(1S,5-dimethyl-4-hexenyl)-3aalpha,4,4aalpha,5,6,7,8,8a,9,9aalpha-decahydro-5,8abeta-dimethyl-5-methylenspirooct-5-en-2,3(2H)-naphtho<2,3-b>furan>-2-on
(22E,24R)-3alpha-ureido-ergosta-4,6,8(14)22-tetraene
7beta-(1S,5-dimethyl-4-hexenyl)-3aalpha,5,6,7,8,8a,9,9aalpha-octahydro-5,5beta,8abeta-trimethylspiro(bicyclo[2.2.2]oct-5-en-2,3(2H)-naphtho[2,3-b]furan)-2-on|7beta-(1S,5-dimethyl-4-hexenyl)-3aalpha,5,6,7,8,8a,9,9aalpha-octahydro-5,5beta,8abeta-trimethylspirooct-5-en-2,3(2H)-naphtho<2,3-b>furan>-2-on
(13Z,15E,17E,22E)-3beta-hydroxymalabarica-13,15,17,22,24-pentaen-12-one
Manglupenone
Ergosta-5,7,22,24(28)-tetraen-3beta-yl acetate
A sterol ester that is ergosta-5,7,22,24(28)-tetraen-3beta-ol in which the hydroxyl hydrogen is substituted by an acetyl group.
[3-carboxy-2-[(10E,13E,16E)-nonadeca-10,13,16-trienoyl]oxypropyl]-trimethylazanium
(22S,24R)-3alpha-ureido-ergosta-4,6,8(14),22-tetraene
A member of the class of ureas that is urea substituted by a (3beta,22E)-ergosta-4,6,8(14),22-tetraen-3-yl group at position 1. Isolated from the fruit bodies of the fungus Chlorophyllum molybdites, it exhibits cytotoxicity against Kato III cells.
(6Z,9Z,12Z,15Z,18Z,21Z,24Z,27Z)-triaconta-6,9,12,15,18,21,24,27-octaenoic acid
L-365260 (hemihydrate)
L-365260 hemihydrate is an orally active and selective antagonist of non-peptide gastrin and brain cholecystokinin receptor (CCK-B), with Kis of 1.9 nM and 2.0 nM, respectively. L-365260 hemihydrate interacts in a stereoselective and competitive manner with guinea pig stomach gastrin and brain CCK receptors[1][2][3].
