Exact Mass: 431.0884078

Exact Mass Matches: 431.0884078

Found 1 metabolites which its exact mass value is equals to given mass value 431.0884078, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

TP0463518

TP0463518

C20H18ClN3O6 (431.0884078)


TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2 with an IC50 value of 22 nM[1].