Exact Mass: 426.244
Exact Mass Matches: 426.244
Found 102 metabolites which its exact mass value is equals to given mass value 426.244
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Oxatomide
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AE - Piperazine derivatives D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents Oxatomide is a first-generation piperazine H1-antihistamine. D018926 - Anti-Allergic Agents Oxatomide is a potent and orally active dual H1-histamine receptor and P2X7 receptor antagonist with antihistamine and anti-allergic activity. Oxatomide almost completely blocks the ATP-induced current in human P2X7 receptors (IC50 of 0.95 μM). Oxatomide inhibits ATP-induced Ca2+ influx with an IC50 value of 0.43 μM and also inhibits serotonin[1][2].
Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)amino)propyl)-4-hydroxy-3-methoxy-alpha-(1-methylethyl)-
(4S,7R)-7-[(1E,3E,5E,7E)-8-[(2S,5R,6S)-5,6-dihydro-5-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl]nona-1,3,5,7-tetraen-1-yl]-4,6,7-trimethyl-2-oxabicyclo[2.2.1]heptane-3,5-dione|wortmannilactone F
(5Z,8Z,11Z,13E,17Z)-2-eicosa-15(S)-hydroxy-5,8,11,13,17-pentaenoylphloroglucinol
7alpha,21-dihydroxy-3-oxo-24,25,26,27-tetranorapotirucall-1,14,20(22)-trien-21,23-olide
16beta-acetyloxy-14-hydroxy-bufa-5,20,22-trienolide
(5beta,9alpha,10alpha)-7-O-(3alpha-methoxy-8(12)-drimen-11-yl)-scopoletin|driportlandin
Ile Pro Pro Thr
Ile Pro Thr Pro
Ile Thr Pro Pro
Leu Pro Pro Thr
Leu Pro Thr Pro
Leu Thr Pro Pro
Pro Ile Pro Thr
Pro Ile Thr Pro
Pro Leu Pro Thr
Pro Leu Thr Pro
Pro Pro Ile Thr
Pro Pro Leu Thr
Pro Pro Thr Ile
Pro Pro Thr Leu
Pro Thr Ile Pro
Pro Thr Leu Pro
Pro Thr Pro Ile
Pro Thr Pro Leu
Thr Ile Pro Pro
Thr Leu Pro Pro
Thr Pro Ile Pro
Thr Pro Leu Pro
Thr Pro Pro Ile
Thr Pro Pro Leu
2-eicosa-15S-hydroxy-5Z,8Z,11Z,13E,17Z-pentaenoylphloroglucinol
10,15-Dihydro-5,5,10,10,15,15-hexamethyl-5H-tribenzo[a,f,k]trindene
1,3-diisocyanato-2-methylbenzene,2-ethyl-2-(hydroxymethyl)propane-1,3-diol,hexane-1,6-diol
oxatomide
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AE - Piperazine derivatives D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents D018926 - Anti-Allergic Agents Oxatomide is a potent and orally active dual H1-histamine receptor and P2X7 receptor antagonist with antihistamine and anti-allergic activity. Oxatomide almost completely blocks the ATP-induced current in human P2X7 receptors (IC50 of 0.95 μM). Oxatomide inhibits ATP-induced Ca2+ influx with an IC50 value of 0.43 μM and also inhibits serotonin[1][2].
N-[3-(diethylamino)propyl]-4-[(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazo]-4-oxobutanamide
(3aS,5S,9aS)-2-[(2-methylphenyl)methyl]-5-(1-methyl-3-phenyl-4-pyrazolyl)-3a,4,5,7,8,9-hexahydro-3H-pyrrolo[3,4-h]pyrrolizin-1-one
1-(4-Azidobenzyl)-4-[2-(diphenylmethoxy)ethyl]piperidine
2,3-dihydroxypropyl [2-hydroxy-3-[(Z)-tridec-9-enoxy]propyl] hydrogen phosphate
SB269652
SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor (D2R); a new chemical probe that can differentiate D2R monomers from dimers or oligomers depending on the observed pharmacology. IC50 value: 0.2/0.5 nM [1] Target: D3 receptor antagonist SB269,652 potently (low nanomolar range) abolished specific binding of [(3)H]nemanopride and [(3)H]spiperone to Chinese hamster ovary-transfected D(3) receptors when radioligands were used at 0.2 and 0.5 nM, respectively. However, even at high concentrations (5 μM), SB269,652 only submaximally inhibited the specific binding of these radioligands when they were employed at 10-fold higher concentrations. By analogy, although SB269,652 potently blocked D(3) receptor-mediated activation of Gα(i3) and phosphorylation of extracellular-signal-regulated kinase (ERK)1/2, when concentrations of dopamine were increased by 10-fold, from 1 μM to 10 μM, SB269,652 only submaximally inhibited dopamine-induced stimulation of Gα(i3) [1].