Exact Mass: 419.0250680000001

Exact Mass Matches: 419.0250680000001

Found 2 metabolites which its exact mass value is equals to given mass value 419.0250680000001, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

(Rac)-PT2399

(Rac)-PT2399

C17H10F5NO4S (419.0250680000001)


(Rac)-PT2399 (Compound 10e), the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM[1].

   

PT2399

PT2399

C17H10F5NO4S (419.0250680000001)


PT2399 is a potent and selective HIF-2α antagonist, which directly binds to HIF-2α PAS B domain with an IC50 of 6 nM. PT2399 displays potent antitumor activity in vivo[1][2][3].