Exact Mass: 414.1777

Exact Mass Matches: 414.1777

Found 5 metabolites which its exact mass value is equals to given mass value 414.1777, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

GR 159897

GR 159897

C23H27FN2O2S (414.1777)


GR 159897 is a highly potent, selective, competitive, brain-penetrated non-peptide neurokinin 2 (NK2) receptor antagonist. GR 159897 has little or no affinity for NK1 and NK3 receptors. GR 159897 inhibits binding of [3H]GR100679 to human NK2 (hNK2)-CHO cells and rat colon membranes with pKis of 9.51 and 10, respectively. Antagonizes bronchoconstriction. Anxiolytic-like and anti-tumor effects[1][2].

   

5-Fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulphinyl]methyl]-1-piperidinyl]ethyl]-1H-indole

5-Fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulphinyl]methyl]-1-piperidinyl]ethyl]-1H-indole

C23H27FN2O2S (414.1777)


   

5-bromo-14-isopropyl-11-methoxy-4,8-dimethyltetracyclo[10.2.1.0¹,¹⁰.0⁴,⁹]pentadecane-7,8-diol

5-bromo-14-isopropyl-11-methoxy-4,8-dimethyltetracyclo[10.2.1.0¹,¹⁰.0⁴,⁹]pentadecane-7,8-diol

C21H35BrO3 (414.1769)


   

(1s,4s,5s,7s,8s,9s,10s,11s,12s,14s)-5-bromo-14-isopropyl-11-methoxy-4,8-dimethyltetracyclo[10.2.1.0¹,¹⁰.0⁴,⁹]pentadecane-7,8-diol

(1s,4s,5s,7s,8s,9s,10s,11s,12s,14s)-5-bromo-14-isopropyl-11-methoxy-4,8-dimethyltetracyclo[10.2.1.0¹,¹⁰.0⁴,⁹]pentadecane-7,8-diol

C21H35BrO3 (414.1769)