Exact Mass: 411.10865540000003

Exact Mass Matches: 411.10865540000003

Found 1 metabolites which its exact mass value is equals to given mass value 411.10865540000003, within given mass tolerance error 3.2E-7 dalton. Try search metabolite list with more accurate mass tolerance error 6.4E-8 dalton.

VU6019650

VU6019650

C18H22FN3O3S2 (411.10865540000003)


VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR (IC50=36 nM), can be used for opioid use disorder (OUD) relief. VU6019650 can cross blood brain barrier, potentially modulates the mesolimbic dopaminergic reward circuitry. VU6019650 blocks Oxotremorine M iodide (HY-101372A) induced increases of neuronal firing rates of midbrain dopamine neurons in the ventral tegmental area (VTA)[1][2].