Exact Mass: 411.10865540000003
Exact Mass Matches: 411.10865540000003
Found 1 metabolites which its exact mass value is equals to given mass value 411.10865540000003,
within given mass tolerance error 2.048E-11 dalton. Try search metabolite list with more accurate mass tolerance error
4.096E-12 dalton.
VU6019650
VU6019650
VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR (IC50=36 nM), can be used for opioid use disorder (OUD) relief. VU6019650 can cross blood brain barrier, potentially modulates the mesolimbic dopaminergic reward circuitry. VU6019650 blocks Oxotremorine M iodide (HY-101372A) induced increases of neuronal firing rates of midbrain dopamine neurons in the ventral tegmental area (VTA)[1][2].
