Exact Mass: 411.10865540000003

Exact Mass Matches: 411.10865540000003

Found 1 metabolites which its exact mass value is equals to given mass value 411.10865540000003, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

VU6019650

VU6019650

C18H22FN3O3S2 (411.10865540000003)


VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR (IC50=36 nM), can be used for opioid use disorder (OUD) relief. VU6019650 can cross blood brain barrier, potentially modulates the mesolimbic dopaminergic reward circuitry. VU6019650 blocks Oxotremorine M iodide (HY-101372A) induced increases of neuronal firing rates of midbrain dopamine neurons in the ventral tegmental area (VTA)[1][2].