Exact Mass: 407.1183768

Exact Mass Matches: 407.1183768

Found 11 metabolites which its exact mass value is equals to given mass value 407.1183768, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

Sitagliptin

(2R)-4-oxo-4-[3-(TRIFLUOROMETHYL)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine

C16H15F6N5O (407.11807319999997)


Sitagliptin is a new oral hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. This enzyme-inhibiting drug is to be used either alone or in combination with metformin or a thiazolidinedione for control of type 2 diabetes mellitus. The drug works to competitively inhibit a protein/enzyme, dipeptidyl peptidase 4 (DPP-4), that results in an increased amount of active incretins (GLP-1 and GIP), reduced amount of release of glucagon (diminishes its release) and increased release of insulin. A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BH - Dipeptidyl peptidase 4 (dpp-4) inhibitors C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C98086 - Dipeptidyl Peptidase-4 Inhibitor D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D054795 - Incretins COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D007004 - Hypoglycemic Agents > D054873 - Dipeptidyl-Peptidase IV Inhibitors D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors C471 - Enzyme Inhibitor > C783 - Protease Inhibitor Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

rac-Sitagliptin

4-oxo-4-(3-(Trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine

C16H15F6N5O (407.11807319999997)


   

Sitagliptin

Sitagliptin

C16H15F6N5O (407.11807319999997)


A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BH - Dipeptidyl peptidase 4 (dpp-4) inhibitors C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C98086 - Dipeptidyl Peptidase-4 Inhibitor D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D054795 - Incretins COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D007004 - Hypoglycemic Agents > D054873 - Dipeptidyl-Peptidase IV Inhibitors D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors C471 - Enzyme Inhibitor > C783 - Protease Inhibitor Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 84 CONFIDENCE standard compound; INTERNAL_ID 2257 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2903

   

Fmoc-(R)-3-Amino-4-(2-thienyl)-butyric acid

Fmoc-(R)-3-Amino-4-(2-thienyl)-butyric acid

C23H21NO4S (407.1191226000001)


   

Fmoc-(S)-3-Amino-4-(3-thienyl)-butyric acid

Fmoc-(S)-3-Amino-4-(3-thienyl)-butyric acid

C23H21NO4S (407.1191226000001)


   

Fmoc-(R)-3-Amino-4-(3-thienyl)-butyric acid

Fmoc-(R)-3-Amino-4-(3-thienyl)-butyric acid

C23H21NO4S (407.1191226000001)


   

Fmoc-(S)-3-Amino-4-(2-thienyl)-butyric acid

Fmoc-(S)-3-Amino-4-(2-thienyl)-butyric acid

C23H21NO4S (407.1191226000001)


   

7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrazine

7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrazine

C16H15F6N5O (407.11807319999997)


   

Cyclohexylmethyl-[3-[1-(3,4-dichlorophenyl)ethylamino]-2-hydroxypropyl]phosphinic acid

Cyclohexylmethyl-[3-[1-(3,4-dichlorophenyl)ethylamino]-2-hydroxypropyl]phosphinic acid

C18H28Cl2NO3P (407.1183768)


   

5,6-dimethoxy-4,7-bis(4-methoxyphenyl)-1,3-benzothiazole

5,6-dimethoxy-4,7-bis(4-methoxyphenyl)-1,3-benzothiazole

C23H21NO4S (407.1191226000001)