Exact Mass: 403.1429

Exact Mass Matches: 403.1429

Found 116 metabolites which its exact mass value is equals to given mass value 403.1429, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Perphenazine

2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol

C21H26ClN3OS (403.1485)

Perphenazine is only found in individuals that have used or taken this drug. It is an antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine. [PubChem]Binds to the dopamine D1 and dopamine D2 receptors and inhibits their activity. The mechanism of the anti-emetic effect is due predominantly to blockage of the dopamine D2 neurotransmitter receptors in the chemoreceptor trigger zone and vomiting centre. Perphenazine also binds the alpha andrenergic receptor. This receptors action is mediated by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. N - Nervous system > N05 - Psycholeptics > N05A - Antipsychotics > N05AB - Phenothiazines with piperazine structure D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent Perphenazine is an orally active dopamine receptor and histamine-1 receptor antagonist, with Ki values of 0.56 nM (D2), 0.43 nM (D3), 6 nM (5-HT2A), respectively. Perphenazine also binds to Alpha-1A adrenergic receptor. Perphenazine inhibits cancer cell proliferation, and induces apoptosis. Perphenazine can be used in the research of mental disease, cancer, inflammation[1][3][5].

Hydroxyethylflurazepam

7-chloro-1-{2-[ethyl(2-hydroxyethyl)amino]ethyl}-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one

C21H23ClFN3O2 (403.1463)

(2Z)-2-methylbut-2-enoic acid rel-(7R,9S)-7,8,9,10-tetrahydro-5-hydroxy-7-(1-hydroxy-1-methylethyl)-4-methyl-10-methyleneoxepino[2,3-g]benzothiazol-9-yl ester|(8beta,10alpha)-8-(angeloyloxy)-5,10-epoxythiazolo[5,4-a]bisabola-1,3,5,7(14)-tetraene-4,11-diol

(2Z)-2-methylbut-2-enoic acid rel-(7R,9S)-7,8,9,10-tetrahydro-5-hydroxy-7-(1-hydroxy-1-methylethyl)-4-methyl-10-methyleneoxepino[2,3-g]benzothiazol-9-yl ester|(8beta,10alpha)-8-(angeloyloxy)-5,10-epoxythiazolo[5,4-a]bisabola-1,3,5,7(14)-tetraene-4,11-diol

C21H25NO5S (403.1453)

3-(L-alanyl-L-homoserinyl-L-aspartyl-betacarboxy)-4-hydroxy-5-oxopyrazole

C14H21N5O9 (403.1339)

meta-topolin 9-glucoside

C18H21N5O6 (403.1492)

2-(5-hydroxy-1,6-dioxo-7-phenyl-1H,6H-benzo[de]isoquinolin-2-yl)-3-methyl-pentanoic acid|N-(1-Carboxy-2-methylbutyl)-lachnanthopyridon

C24H21NO5 (403.142)

ortho-topolin-9-glucoside

C18H21N5O6 (403.1492)

perphenazine

Perphenazine aka 2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol

C21H26ClN3OS (403.1485)

N - Nervous system > N05 - Psycholeptics > N05A - Antipsychotics > N05AB - Phenothiazines with piperazine structure D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C29710 - Antipsychotic Agent Perphenazine is an orally active dopamine receptor and histamine-1 receptor antagonist, with Ki values of 0.56 nM (D2), 0.43 nM (D3), 6 nM (5-HT2A), respectively. Perphenazine also binds to Alpha-1A adrenergic receptor. Perphenazine inhibits cancer cell proliferation, and induces apoptosis. Perphenazine can be used in the research of mental disease, cancer, inflammation[1][3][5].

Ala Cys Asn Pro

(2S)-1-[(2S)-2-[(2R)-2-[(2S)-2-aminopropanamido]-3-sulfanylpropanamido]-3-carbamoylpropanoyl]pyrrolidine-2-carboxylic acid