Exact Mass: 400.07473339999996
Exact Mass Matches: 400.07473339999996
Found 1 metabolites which its exact mass value is equals to given mass value 400.07473339999996,
within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error
0.0002 dalton.
MRK-898
MRK-898
C20H9F5N4 (400.07473339999996)
MRK-898 is an orally active GABA(A) receptor modulator. MRK-898 binds to α1, α2, α3 or α5 subunit of GABA(A) receptor with Ki values of 1.2 nM, 1.0 nM, 0.73 nM, and 0.50 nM, respectively. However, α1-containing GABA(A) receptors are identified as the "sedative" and α2- and/or α3-containing receptors as the "anxiolytic" subtype(s)[1].