Exact Mass: 400.038708
Exact Mass Matches: 400.038708
Found 4 metabolites which its exact mass value is equals to given mass value 400.038708,
within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error
0.0002 dalton.
5-(5-Iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
5-[5-iodo-4-methoxy-2-(propan-2-yl)phenoxy]pyrimidine-2,4-diamine
af-353
2,4-Pyrimidinediamine, 5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-
AF-353 (Ro-4) is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3[1][2].