Exact Mass: 393.1607804
Exact Mass Matches: 393.1607804
Found 148 metabolites which its exact mass value is equals to given mass value 393.1607804,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Erlotinib
C22H23N3O4 (393.16884780000004)
Erlotinib hydrochloride (trade name Tarceva, Genentech/OSIP, originally coded as OSI-774) is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. Similar to gefitinib, erlotinib specifically targets the epidermal growth factor receptor (EGFR) tyrosine kinase. It binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. Erlotinib has recently been shown to be a potent inhibitor of JAK2V617F activity. JAK2V617F is a mutant of tyrosine kinase JAK2, is found in most patients with polycythemia vera (PV) and a substantial proportion of patients with idiopathic myelofibrosis or essential thrombocythemia. The study suggests that erlotinib may be used for treatment of JAK2V617F-positive PV and other myeloproliferative disorders. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01E - Protein kinase inhibitors > L01EB - Epidermal growth factor receptor (egfr) tyrosine kinase inhibitors C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C163952 - EGFR-targeting Agent C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors D000970 - Antineoplastic Agents
6'-Apiosyllotaustralin
C16H27NO10 (393.16348819999996)
6-Apiosyllotaustralin is found in root vegetables. 6-Apiosyllotaustralin is a constituent of the roots of Manihot esculenta (cassava). Constituent of the roots of Manihot esculenta (cassava). 6-Apiosyllotaustralin is found in root vegetables.
Epoxyfumitremorgin C
C22H23N3O4 (393.16884780000004)
Epoxyfumitremorgin C is from Aspergillus fumigatus. From Aspergillus fumigatus
gamma-Glutamylfelinylglycine
1-[5-(2-Cyclopropyl-5,7-dimethylimidazo[4,5-b]pyridin-3-ylmethyl)thiophen-2-yl]cyclopent-3-ene carboxylic acid
6-methoxyspirotryprostatin B
C22H23N3O4 (393.16884780000004)
An indole alkaloid isolated from a marine-derived fungal strain Aspergillus sydowii PFW1-13 and has been shown to exhibit cytotoxic activity.
2-((6-O-(beta-D-apiofuranosyl)-beta-D-glucopyranosyl)oxy)-2-methylbutanenitrile
C16H27NO10 (393.16348819999996)
6-(1-hydroxyethyl)-5,6-dihydrochelerythrine
C23H23NO5 (393.15761480000003)
6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine
C23H23NO5 (393.15761480000003)
Cys Gly Lys Ser
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Gly Gly Asn Phe
Gly Lys Cys Ser
Gly Lys Ser Cys
Gly Asn Phe Gly
Gly Asn Gly Phe
Gly Ser Cys Lys
Gly Ser Lys Cys
Lys Cys Gly Ser
Lys Cys Ser Gly
Lys Gly Cys Ser
Lys Gly Ser Cys
Lys Ser Cys Gly
Lys Ser Gly Cys
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Tarceva
C22H23N3O4 (393.16884780000004)
6'-Apiosyllotaustralin
C16H27NO10 (393.16348819999996)
Epoxyfumitremorgin C
C22H23N3O4 (393.16884780000004)
(2S)-2-acetamido-N-[(2S)-1-[[(2S)-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]propanamide
Urea, N-[(2-chloro-6,8-dimethyl-3-quinolinyl)methyl]-N-(2-methylphenyl)-N-2-propenyl- (9CI)
21-Amino-17-hydroxypregna-1,4-diene-3,11,20-trione hydrochloride
C21H28ClNO4 (393.1706758000001)
5-(6-(BENZYLOXY)NAPHTHALEN-2-YL)-2,2-DIMETHYL-5-NITRO-1,3-DIOXANE
C23H23NO5 (393.15761480000003)
4-Cyanophenyl 4-(6-acryloyloxyhexyloxy)benzoate
C23H23NO5 (393.15761480000003)
3-(7-CYANO-5-(2-NITROPROPYL)INDOLIN-1-YL)PROPYL BENZOATE
C22H23N3O4 (393.16884780000004)
METHYL 4-(4-METHYL-5-(2-(TRIFLUOROMETHYL)PHENYL)-4H-1,2,4-TRIAZOL-3-YL)BICYCLO[2.2.2]OCTANE-1-CARBOXYLATE
7-[2-[[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]amino]ethyl]-1,3-dimethylpurine-2,6-dione,hydrochloride
C18H24ClN5O3 (393.15675840000006)
Nalbuphine Hydrochloride
C21H28ClNO4 (393.1706758000001)
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist D002491 - Central Nervous System Agents > D000700 - Analgesics
9H-Purine-9-acetic acid, 6-[bis[(1,1-diMethylethoxy)carbonyl]aMino]-
4-(4-CBZ-PIPERAZIN-1-YL-METHYL)-2-TRIFLUOROMETHYLANILINE
4-(3-(4-(1-methyl-1H-pyrazol-5-yl)phenylthio)phenyl)-tetrahydro-2H-pyran-4-carboxamide
PF-4191834 (PF-04191834) is an orally active, noniron chelating, and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) (IC50=229 nM), displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX, shows no activity toward the cyclooxygenase enzymes, and is effective in inflammation and pain[1].
L-seryl-L-tyrosine 2-naphthylamide
C22H23N3O4 (393.16884780000004)
1-(3,4-dihydro-2H-quinolin-1-yl)-2-[[1-(4-ethoxyphenyl)-2-imidazolyl]thio]ethanone
2-((6-O-(beta-D-apiofuranosyl)beta-D-glucopyranosyl)oxy)-2-methylbutanenitrile
C16H27NO10 (393.16348819999996)
3-[(2E,4E,6E)-6,8-dimethyldeca-2,4,6-trienoyl]-1-hydroxy-5-(4-oxidophenyl)-2-oxopyridin-4-olate
C23H23NO5-2 (393.15761480000003)
3-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]-1-phenylpyrrolidine-2,5-dione
C22H23N3O4 (393.16884780000004)
2-amino-3-cyano-5-oxo-1-spiro[7,8-dihydro-6H-1-benzopyran-4,4-piperidine]carboxylic acid (phenylmethyl) ester
C22H23N3O4 (393.16884780000004)
1-[4-(4-Phenylmethoxyphenyl)-2-thiazolyl]-4-piperidinecarboxamide
2,5-Dimethyl-3-furancarboxylic acid [2-(2-ethoxyanilino)-2-oxo-1-phenylethyl] ester
C23H23NO5 (393.15761480000003)
1-(4-fluorophenyl)-3-[(2S,3R,6S)-2-(hydroxymethyl)-6-[2-(4-morpholinyl)-2-oxoethyl]-3,6-dihydro-2H-pyran-3-yl]urea
1-(4-fluorophenyl)-3-[(2R,3S,6R)-2-(hydroxymethyl)-6-[2-(4-morpholinyl)-2-oxoethyl]-3,6-dihydro-2H-pyran-3-yl]urea
1-(4-fluorophenyl)-3-[(2S,3R,6R)-2-(hydroxymethyl)-6-[2-(4-morpholinyl)-2-oxoethyl]-3,6-dihydro-2H-pyran-3-yl]urea
1-(4-fluorophenyl)-3-[(2R,3S,6S)-2-(hydroxymethyl)-6-[2-(4-morpholinyl)-2-oxoethyl]-3,6-dihydro-2H-pyran-3-yl]urea
Cyclohexyl 2-methyl-4-thiophen-2-yl-3,4-dihydropyrimido[1,2-a]benzimidazole-3-carboxylate
(2,5-Dioxopyrrolidin-1-yl) 4-(3,6-diaminoacridin-10-ium-10-yl)butanoate
Erlotinib
C22H23N3O4 (393.16884780000004)
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01E - Protein kinase inhibitors > L01EB - Epidermal growth factor receptor (egfr) tyrosine kinase inhibitors C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C163952 - EGFR-targeting Agent C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors D000970 - Antineoplastic Agents
CJ-13,610
CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM[1]. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid
1-[(6s)-2,3-dihydroxy-7,8-dimethoxy-5-methyl-6h-benzo[c]phenanthridin-6-yl]propan-2-one
C23H23NO5 (393.15761480000003)
7-benzyl-6,10-dihydroxy-4-(sec-butyl)-15-oxa-2,5,8-triazatricyclo[8.5.0.0³,⁸]pentadeca-1,3,5,11,13-pentaen-9-one
C22H23N3O4 (393.16884780000004)
5-ethanimidoyl-4,18-dihydroxy-8,8,16-trimethyl-7,16-diazapentacyclo[9.7.1.0²,⁹.0³,⁷.0¹⁵,¹⁹]nonadeca-1(18),4,11(19),12,14-pentaene-6,17-dione
C22H23N3O4 (393.16884780000004)
20-ethoxy-17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0²,¹⁰.0⁴,⁸.0¹⁴,¹⁹]henicosa-1(13),2,4(8),9,11,14(19),15,17-octaene
C23H23NO5 (393.15761480000003)
(1s)-1-[(20s)-17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0²,¹⁰.0⁴,⁸.0¹⁴,¹⁹]henicosa-1(13),2,4(8),9,11,14,16,18-octaen-20-yl]ethanol
C23H23NO5 (393.15761480000003)
(7s,10r)-7-benzyl-4-[(2r)-butan-2-yl]-6,10-dihydroxy-15-oxa-2,5,8-triazatricyclo[8.5.0.0³,⁸]pentadeca-1,3,5,11,13-pentaen-9-one
C22H23N3O4 (393.16884780000004)
(2r,3s,9r)-5-ethanimidoyl-4,18-dihydroxy-8,8,16-trimethyl-7,16-diazapentacyclo[9.7.1.0²,⁹.0³,⁷.0¹⁵,¹⁹]nonadeca-1(18),4,11(19),12,14-pentaene-6,17-dione
C22H23N3O4 (393.16884780000004)
(4s,7s)-7-benzyl-4,6-dihydroxy-4-(sec-butyl)-15-oxa-2,5,8-triazatricyclo[8.5.0.0³,⁸]pentadeca-1(10),2,5,11,13-pentaen-9-one
C22H23N3O4 (393.16884780000004)
(4s,7s)-7-benzyl-6-hydroxy-4-isopropyl-4-methoxy-15-oxa-2,5,8-triazatricyclo[8.5.0.0³,⁸]pentadeca-1(10),2,5,11,13-pentaen-9-one
C22H23N3O4 (393.16884780000004)
2-hydroxy-6-methoxy-6'-(2-methylprop-1-en-1-yl)-1',7'-diazaspiro[indole-3,5'-tricyclo[7.3.0.0³,⁷]dodecan]-3'-ene-2',8'-dione
C22H23N3O4 (393.16884780000004)
(1s,12s,13r)-12-hydroxy-5-methoxy-12-(2-methoxyphenyl)-6-methyl-16-oxa-7-azatetracyclo[11.2.1.0²,¹¹.0³,⁸]hexadeca-2,5,8,10-tetraen-4-one
C23H23NO5 (393.15761480000003)
(1r,12s,13s)-12-hydroxy-5-methoxy-12-(2-methoxyphenyl)-6-methyl-16-oxa-7-azatetracyclo[11.2.1.0²,¹¹.0³,⁸]hexadeca-2,5,8,10-tetraen-4-one
C23H23NO5 (393.15761480000003)
(1s,12r,13r)-12-hydroxy-5-methoxy-12-(2-methoxyphenyl)-6-methyl-16-oxa-7-azatetracyclo[11.2.1.0²,¹¹.0³,⁸]hexadeca-2,5,8,10-tetraen-4-one
C23H23NO5 (393.15761480000003)
(7s,10s)-7-benzyl-6,10-dihydroxy-4-(sec-butyl)-15-oxa-2,5,8-triazatricyclo[8.5.0.0³,⁸]pentadeca-1,3,5,11,13-pentaen-9-one
C22H23N3O4 (393.16884780000004)
2-{[(2s,3r,4s,5s,6s)-6-{[(2s,3s)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl](hydroxy)methyl}-3,4,5-trihydroxyoxan-2-yl]oxy}-2-methylbutanenitrile
C16H27NO10 (393.16348819999996)
(2z,6z,8s,11s,13e)-11-hydroxy-15-(2-hydroxy-1,3-thiazol-4-yl)-3,8-dimethyl-15-oxopentadeca-2,6,13-trienoic acid
C20H27NO5S (393.1609852000001)
7-benzyl-4,6-dihydroxy-4-(sec-butyl)-15-oxa-2,5,8-triazatricyclo[8.5.0.0³,⁸]pentadeca-1(10),2,5,11,13-pentaen-9-one
C22H23N3O4 (393.16884780000004)
7-benzyl-6-hydroxy-4-isopropyl-4-methoxy-15-oxa-2,5,8-triazatricyclo[8.5.0.0³,⁸]pentadeca-1(10),2,5,11,13-pentaen-9-one
C22H23N3O4 (393.16884780000004)
(7s,10r)-7-benzyl-6-hydroxy-4-isopropyl-10-methoxy-15-oxa-2,5,8-triazatricyclo[8.5.0.0³,⁸]pentadeca-1,3,5,11,13-pentaen-9-one
C22H23N3O4 (393.16884780000004)
(3s,6's,9's)-2-hydroxy-6-methoxy-6'-(2-methylprop-1-en-1-yl)-1',7'-diazaspiro[indole-3,5'-tricyclo[7.3.0.0³,⁷]dodecan]-3'-ene-2',8'-dione
C22H23N3O4 (393.16884780000004)
7-benzyl-6-hydroxy-4-isopropyl-10-methoxy-15-oxa-2,5,8-triazatricyclo[8.5.0.0³,⁸]pentadeca-1,3,5,11,13-pentaen-9-one
C22H23N3O4 (393.16884780000004)
(21r)-5,10,11-trimethoxy-16-azapentacyclo[12.7.0.0²,⁷.0⁸,¹³.0¹⁶,²⁰]henicosa-1(14),2(7),3,5,8(13),9,11,19-octaene-6,21-diol
C23H23NO5 (393.15761480000003)
n-{2-[12-methoxy-11-(methylsulfanyl)-8,14-diazatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(17),2,4,6,9,11,13,15-octaen-10-yl]ethyl}propanimidic acid
1-{17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0²,¹⁰.0⁴,⁸.0¹⁴,¹⁹]henicosa-1(13),2,4(8),9,11,14,16,18-octaen-20-yl}ethanol
C23H23NO5 (393.15761480000003)
5,10,11-trimethoxy-16-azapentacyclo[12.7.0.0²,⁷.0⁸,¹³.0¹⁶,²⁰]henicosa-1(14),2(7),3,5,8(13),9,11,19-octaene-6,21-diol
C23H23NO5 (393.15761480000003)
5,6,7-trimethoxy-4-(4-methoxyphenyl)-1-methyl-3h-naphtho[2,3-d]imidazol-2-imine
C22H23N3O4 (393.16884780000004)
(7s,10s)-7-benzyl-4-[(2r)-butan-2-yl]-6,10-dihydroxy-15-oxa-2,5,8-triazatricyclo[8.5.0.0³,⁸]pentadeca-1,3,5,11,13-pentaen-9-one
C22H23N3O4 (393.16884780000004)