Exact Mass: 393.1044114

Exact Mass Matches: 393.1044114

Found 43 metabolites which its exact mass value is equals to given mass value 393.1044114, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Q-100035

19-ethyl-19-hydroxy-8-nitro-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione

C20H15N3O6 (393.096081)

Rubitecan

(19S)-19-ethyl-19-hydroxy-8-nitro-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione

C20H15N3O6 (393.096081)

Rubitecan is a pyranoindolizinoquinoline that is camptothecin in which the hydrogen at position 9 has been replaced by a nitro group. It is a prodrug for 9-aminocamptothecin. It has a role as an antineoplastic agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a prodrug. It is a pyranoindolizinoquinoline, a C-nitro compound, a semisynthetic derivative, a tertiary alcohol and a delta-lactone. Rubitecan is a semisynthetic agent related to camptothecin with potent antitumor and antiviral properties. Rubitecan binds to and inhibits the enzyme topoisomerase I and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells; this agent also prevents repair of reversible single-strand DNA breaks. (NCI04) C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059004 - Topoisomerase I Inhibitors C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor > C1748 - Topoisomerase Inhibitor D004791 - Enzyme Inhibitors Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells[1][2][3].

CAY10571

4-[5-(4-fluorophenyl)-2-[4-9methylsulfonyl)phenyl]-1H-imidazol-4-yl]-pyridine

C21H16FN3O2S (393.0947208)

9-nitro-20(S)-camptothecin

C20H15N3O6 (393.096081)

Annotation level-1

h_255_rad140

C20H16ClN5O2 (393.0992466)

bis[4-(1,1-dimethylethyl)phenyl]-Iodonium

C20H26I+ (393.1079166)

9-nitrocamptothecin

C20H15N3O6 (393.096081)

Fmoc-β-(2-thienyl)-D-alanine

C22H19NO4S (393.1034734000001)

3-Butyl-1,1,2-trimethyl-1H-benz[e]indolium iodide

C19H24IN (393.0953414)

FMOC-3-L-ALA(2-THIENYL)-OH

C22H19NO4S (393.1034734000001)

Fmoc-(R)-3-Amino-3-(2-thienyl)-propionic acid

C22H19NO4S (393.1034734000001)

7-[(3R)-3-isothiocyanatopyrrolidin-1-yl]-N,N-dimethyl-2,1,3-benzoxadiazole-4-sulfonamide

C16H19N5O5S (393.1106844)

Fmoc-D-3-Thienylalanine

C22H19NO4S (393.1034734000001)

4,4,4-(1,3,5-Triazine-2,4,6-triyl)tris[benzaldehyde]

C24H15N3O3 (393.11133600000005)

FMoc-L-3-Thienylalanine

C22H19NO4S (393.1034734000001)

Testolone

C20H16ClN5O2 (393.0992466)

C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist > C242 - Anti-Androgen C274 - Antineoplastic Agent > C129818 - Antineoplastic Hormonal/Endocrine Agent

Rel-(9R,12S)-9,10,11,12-tetrahydro-9,12-epoxy-1H-diindolo[1,2,3-FG:3,2,1-KL]pyrrolo[3,4-I][1,6]benzodiazocine-1,3(2H)-dione

C24H15N3O3 (393.11133600000005)