Exact Mass: 383.04391080000005
Exact Mass Matches: 383.04391080000005
Found 5 metabolites which its exact mass value is equals to given mass value 383.04391080000005,
within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error
4.0E-5 dalton.
3-{[(1s)-2,2-Difluoro-1-Hydroxy-7-(Methylsulfonyl)-2,3-Dihydro-1h-Inden-4-Yl]oxy}-5-Fluorobenzonitrile
C17H12F3NO4S (383.04391080000005)
Belzutifan
C17H12F3NO4S (383.04391080000005)
Belzutifan
C17H12F3NO4S (383.04391080000005)
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents D000970 - Antineoplastic Agents Belzutifan (PT2977) is an orally active and selective HIF-2α inhibitor with an IC50 of 9 nM. Belzutifan, as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile. Belzutifan is a potential treatment for clear cell renal cell carcinoma (ccRCC)[1].
3-{[(1s)-2,2-Difluoro-1-Hydroxy-7-(Methylsulfonyl)-2,3-Dihydro-1h-Inden-4-Yl]oxy}-5-Fluorobenzonitrile
C17H12F3NO4S (383.04391080000005)
PT-2385
C17H12F3NO4S (383.04391080000005)
PT-2385 is a selective HIF-2α inhibitor with a Ki of less than 50 nM[1][2].
