Exact Mass: 381.09880080000005

Exact Mass Matches: 381.09880080000005

Found 1 metabolites which its exact mass value is equals to given mass value 381.09880080000005, within given mass tolerance error 1.6E-6 dalton. Try search metabolite list with more accurate mass tolerance error 3.2E-7 dalton.

PI3K/Akt/CREB activator 1

PI3K/Akt/CREB activator 1

C19H15F4NO3 (381.09880080000005)


PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD)[1].