Exact Mass: 381.09880080000005

Exact Mass Matches: 381.09880080000005

Found 1 metabolites which its exact mass value is equals to given mass value 381.09880080000005, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

PI3K/Akt/CREB activator 1

PI3K/Akt/CREB activator 1

C19H15F4NO3 (381.09880080000005)


PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD)[1].