Exact Mass: 371.0746072
Exact Mass Matches: 371.0746072
Found 5 metabolites which its exact mass value is equals to given mass value 371.0746072,
within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error
4.0E-5 dalton.
1-{4-[3,5-DI(TRIFLUOROMETHYL)PHENOXY]PHENYL}-1H-PYRROLE
AS1949490
C20H18ClNO2S (371.07467180000003)
AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC50 values of 0.34, 0.62, 13, >50, >50, and >50 μM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes[1][2].
