Exact Mass: 367.049
Exact Mass Matches: 367.049
Found 4 metabolites which its exact mass value is equals to given mass value 367.049,
within given mass tolerance error 8.0E-6 dalton. Try search metabolite list with more accurate mass tolerance error
1.6E-6 dalton.
3-(4-Methylsulfonylphenyl)-4-phenyl-5-trifluoromethylisoxazole
3-(4-Methanesulphonylphenyl)-4-phenyl-5-(trifluoromethyl)-1,2-oxazole
3-(4-Methylsulfonylphenyl)-4-phenyl-5-trifluoromethylisoxazole
3-(4-Methylsulfonylphenyl)-4-phenyl-5-trifluoromethylisoxazole
CAY10404 is a potent and selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 1 nM and a selectivity index (SI; COX-1 IC50/COX-2 IC50) of >500000. CAY10404 is a potent PKB/Akt and MAPK signaling pathways inhibitor and induces apoptosis in non-small cell lung cancer (NSCLC) cells. CAY10404, a diarylisoxazole, has good analgesic, anti-inflammatory, and anti-cancer activities[1][2][3].
