Exact Mass: 367.04899580000006
Exact Mass Matches: 367.04899580000006
Found 5 metabolites which its exact mass value is equals to given mass value 367.04899580000006,
within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error
0.0002 dalton.
3-(4-Methylsulfonylphenyl)-4-phenyl-5-trifluoromethylisoxazole
C17H12F3NO3S (367.04899580000006)
CAY10404
C17H12F3NO3S (367.04899580000006)
3-(4-Methylsulfonylphenyl)-4-phenyl-5-trifluoromethylisoxazole
C17H12F3NO3S (367.04899580000006)
CAY10404 is a potent and selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 1 nM and a selectivity index (SI; COX-1 IC50/COX-2 IC50) of >500000. CAY10404 is a potent PKB/Akt and MAPK signaling pathways inhibitor and induces apoptosis in non-small cell lung cancer (NSCLC) cells. CAY10404, a diarylisoxazole, has good analgesic, anti-inflammatory, and anti-cancer activities[1][2][3].