Exact Mass: 362.1065

Exact Mass Matches: 362.1065

Found 1 metabolites which its exact mass value is equals to given mass value 362.1065, within given mass tolerance error 8.0E-6 dalton. Try search metabolite list with more accurate mass tolerance error 1.6E-6 dalton.

L-745870 (hydrochloride)

L-745870 (hydrochloride)

C18H20Cl2N4 (362.1065)


L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors[1][2][3].