Exact Mass: 362.1065

Exact Mass Matches: 362.1065

Found 1 metabolites which its exact mass value is equals to given mass value 362.1065, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

L-745870 (hydrochloride)

L-745870 (hydrochloride)

C18H20Cl2N4 (362.1065)


L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors[1][2][3].