Exact Mass: 354.1492
Exact Mass Matches: 354.1492
Found 5 metabolites which its exact mass value is equals to given mass value 354.1492,
within given mass tolerance error 8.0E-6 dalton. Try search metabolite list with more accurate mass tolerance error
1.6E-6 dalton.
4-Amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide
4-Amino-8-(2-fluoro-6-methoxy-phenyl)-N-propylcinnoline-3-carboxamide
AZD7325 is a potent and orally active partial selective PAM of GABAAα2 and Aα3 receptor (Ki=0.3 and 1.3 nM, respectively), and has less antagonistic efficacy at the Aα1?and Aα5?receptor subtypes[1][4]. AZD7325 is a moderate?CYP1A2?and a potent?CYP3A4?inducer in vitro[2]. AZD7325 has the potential for the investigation of anxiety and dravet syndrome[3]. PAM: positive allosteric modulator.
5-(4-fluorophenyl)-N-({5H,6H,7H,8H,9H-[1,2,4]triazolo[4,3-a]azepin-3-yl}methyl)furan-2-carboxamide
5-(4-fluorophenyl)-N-({5H,6H,7H,8H,9H-[1,2,4]triazolo[4,3-a]azepin-3-yl}methyl)furan-2-carboxamide
2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]-N-(3-fluorophenyl)acetamide
2-[ethyl-[(4-oxo-1H-quinazolin-2-yl)methyl]amino]-N-(3-fluorophenyl)acetamide
