Exact Mass: 352.1223

Exact Mass Matches: 352.1223

Found 4 metabolites which its exact mass value is equals to given mass value 352.1223, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

   

A-582941 (dihydrochloride)

A-582941 (dihydrochloride)

C17H22Cl2N4 (352.1221)


A-582941 dihydrochloride is a potent, selective and brain-penetrant partial agonist of α7 nAChR, with Kis of 10.8 and 16.7 nM in rat brain membranes and human frontal cortex, respectively. A-582941 dihydrochloride also binds to human 5-HT3 receptor with a Ki of 150 nM. A-582941 has the potential for cognitive deficits associated with various neurodegenerative and psychiatric disorders research[1][2].

   

JNJ-46778212

JNJ-46778212

C20H17FN2O3 (352.1223)


JNJ-46778212 (VU 0409551) is an mGlu5 positive allosteric modulator with an EC50 of 260 nM.

   

Ro 10-5824 (dihydrochloride)

Ro 10-5824 (dihydrochloride)

C17H22Cl2N4 (352.1221)


Ro 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist, with Ki of 5.2 nM.