Exact Mass: 350.2331212
Exact Mass Matches: 350.2331212
Found 500 metabolites which its exact mass value is equals to given mass value 350.2331212,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
(S)-[10]-Gingerol
(10)-Gingerol is a beta-hydroxy ketone, a member of phenols and a monomethoxybenzene. (10)-Gingerol is a natural product found in Zingiber officinale with data available. See also: Ginger (part of). (S)-[10]-Gingerol is found in ginger. (S)-[10]-Gingerol is a constituent of ginger, the rhizome of Zingiber officinale. Constituent of ginger, the rhizome of Zingiber officinale. (S)-[10]-Gingerol is found in herbs and spices and ginger. 10-Gingerol is a major pungent constituent in the ginger oleoresin from fresh rhizome, with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM[1][2]. 10-Gingerol is a major pungent constituent in the ginger oleoresin from fresh rhizome, with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM[1][2].
Tetrahydrocorticosterone
Tetrahydrocorticosterone belongs to the class of organic compounds known as 21-hydroxysteroids. These are steroids carrying a hydroxyl group at the 21-position of the steroid backbone. Thus, tetrahydrocorticosterone is considered to be a steroid lipid molecule. Tetrahydrocorticosterone is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. Tetrahydrocorticosterone is one of the major urinary metabolites from corticosterone. Premenopausal patients with early breast cancer excrete subnormal amounts of tetrahydrocorticosterone as compared with the normal subjects of corresponding ages (PMID: 1133844). D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Tetrahydrodeoxycortisol
Tetrahydrodeoxycortisol (THS) is a mineralocorticoid, the main urinary metabolite of 11-deoxycortisol. THS excretion is significantly associated with tetrahydroaldosterone excretion, total androgen excretion, and cortisol metabolites. Aldosterone synthesis is highly heritable and is affected by genotype at CYP11B1. Variation in the region of chromosome 8 including the genes steroid 11-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) influences mineralocorticoid and glucocorticoid metabolism; differences in 11-hydroxylation efficiency can have downstream effects on mineralocorticoid synthesis. Such effects may be of relevance to the development of low-renin essential hypertension. Genotype differences in CYP11B1 explains approx. 5\\% of the variance in urinary THS excretion in the population. Excretion of THS is heritable (19.4\\%) and the T-allele of the −344 C/T polymorphism of CYP11B2 is more strongly assocd. with higher THS levels than the C-allele. (PMID: 16984984, 15522937, 15272911) [HMDB] Tetrahydrodeoxycortisol (THS) is a mineralocorticoid, the main urinary metabolite of 11-deoxycortisol. THS excretion is significantly associated with tetrahydroaldosterone excretion, total androgen excretion, and cortisol metabolites. Aldosterone synthesis is highly heritable and is affected by genotype at CYP11B1. Variation in the region of chromosome 8 including the genes steroid 11-beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) influences mineralocorticoid and glucocorticoid metabolism; differences in 11-hydroxylation efficiency can have downstream effects on mineralocorticoid synthesis. Such effects may be of relevance to the development of low-renin essential hypertension. Genotype differences in CYP11B1 explains approximately 5\\% of the variance in urinary THS excretion in the population. Excretion of THS is heritable (19.4\\%) and the T-allele of the -344 C/T polymorphism of CYP11B2 is more strongly associated with higher THS levels than the C-allele. (PMID: 16984984, 15522937, 15272911). D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
9-fluoro-11,17-dihydroxy-2,17-dimethylandrost-4-en-3-one
Pregnanetriolone
Pregnanetriolone belongs to the family of Sesterterpenes. These are terpenes compsed of five consecutive isoprene units.
Tetrahydro-21-deoxycortisol
5alpha-Androstane-2alpha-fluoro-17beta-ol-3-one acetate
MG(18:4(6Z,9Z,12Z,15Z)/0:0/0:0)
MG(18:4(6Z,9Z,12Z,15Z)/0:0/0:0) is a monoacylglyceride. A monoglyceride, more correctly known as a monoacylglycerol, is a glyceride consisting of one fatty acid chain covalently bonded to a glycerol molecule through an ester linkage. Monoacylglycerol can be broadly divided into two groups; 1-monoacylglycerols (or 3-monoacylglycerols) and 2-monoacylglycerols, depending on the position of the ester bond on the glycerol moiety. Normally the 1-/3-isomers are not distinguished from each other and are termed alpha-monoacylglycerols, while the 2-isomers are beta-monoacylglycerols. Monoacylglycerols are formed biochemically via release of a fatty acid from diacylglycerol by diacylglycerol lipase or hormone sensitive lipase. Monoacylglycerols are broken down by monoacylglycerol lipase. They tend to be minor components only of most plant and animal tissues, and indeed would not be expected to accumulate because their strong detergent properties would have a disruptive effect on membranes. 2-Monoacylglycerols are a major end product of the intestinal digestion of dietary fats in animals via the enzyme pancreatic lipase. They are taken up directly by the intestinal cells and converted to triacylglycerols via the monoacylglycerol pathway before being transported in lymph to the liver. Mono- and Diglycerides are commonly added to commercial food products in small quantities. They act as emulsifiers, helping to mix ingredients such as oil and water that would not otherwise blend well.
5a-Tetrahydrocorticosterone
5a-tetrahydrocorticosterone is highly sensitive to adrenocorticotropic hormone (ACTH) secretion. High levels of 5a-Tetrahydrocorticosterone are a warning sign of hypertension. (PMID: 16597193,7473516). 5a-tetrahydrocorticosterone is highly sensitive to adrenocorticotropic hormone (ACTH) secretion. High levels of 5a-Tetrahydrocorticosterone are a warning sign of hypertension. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
MG(0:0/18:4(6Z,9Z,12Z,15Z)/0:0)
MG(0:0/18:4(6Z,9Z,12Z,15Z)/0:0) is a monoacylglyceride. A monoglyceride, more correctly known as a monoacylglycerol, is a glyceride consisting of one fatty acid chain covalently bonded to a glycerol molecule through an ester linkage. Monoacylglycerol can be broadly divided into two groups; 1-monoacylglycerols (or 3-monoacylglycerols) and 2-monoacylglycerols, depending on the position of the ester bond on the glycerol moiety. Normally the 1-/3-isomers are not distinguished from each other and are termed alpha-monoacylglycerols, while the 2-isomers are beta-monoacylglycerols. Monoacylglycerols are formed biochemically via release of a fatty acid from diacylglycerol by diacylglycerol lipase or hormone sensitive lipase. Monoacylglycerols are broken down by monoacylglycerol lipase. They tend to be minor components only of most plant and animal tissues, and indeed would not be expected to accumulate because their strong detergent properties would have a disruptive effect on membranes. 2-Monoacylglycerols are a major end product of the intestinal digestion of dietary fats in animals via the enzyme pancreatic lipase. They are taken up directly by the intestinal cells and converted to triacylglycerols via the monoacylglycerol pathway before being transported in lymph to the liver. Mono- and Diglycerides are commonly added to commercial food products in small quantities. They act as emulsifiers, helping to mix ingredients such as oil and water that would not otherwise blend well. [HMDB] MG(0:0/18:4(6Z,9Z,12Z,15Z)/0:0) is a monoacylglyceride. A monoglyceride, more correctly known as a monoacylglycerol, is a glyceride consisting of one fatty acid chain covalently bonded to a glycerol molecule through an ester linkage. Monoacylglycerol can be broadly divided into two groups; 1-monoacylglycerols (or 3-monoacylglycerols) and 2-monoacylglycerols, depending on the position of the ester bond on the glycerol moiety. Normally the 1-/3-isomers are not distinguished from each other and are termed alpha-monoacylglycerols, while the 2-isomers are beta-monoacylglycerols. Monoacylglycerols are formed biochemically via release of a fatty acid from diacylglycerol by diacylglycerol lipase or hormone sensitive lipase. Monoacylglycerols are broken down by monoacylglycerol lipase. They tend to be minor components only of most plant and animal tissues, and indeed would not be expected to accumulate because their strong detergent properties would have a disruptive effect on membranes. 2-Monoacylglycerols are a major end product of the intestinal digestion of dietary fats in animals via the enzyme pancreatic lipase. They are taken up directly by the intestinal cells and converted to triacylglycerols via the monoacylglycerol pathway before being transported in lymph to the liver. Mono- and Diglycerides are commonly added to commercial food products in small quantities. They act as emulsifiers, helping to mix ingredients such as oil and water that would not otherwise blend well.
(+)-cis-3-Methylfentanyl
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics
Butanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-
15-Hydroxy-11alpha,9alpha-(epoxymethano)prosta-5,13-dienoic acid
(Z)-7-[(1R,4S,5R,6S)-5-[(E,3R)-3-Hydroxyoct-1-enyl]-2-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid
(5E)-5-[(3Ar,4S,5S,6aR)-5-hydroxy-4-[(E,3R)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid
Adamantylamide-alanyl-isoglutamine
C18H30N4O3 (350.23177899999996)
N-[(S)-[1-(Dimethylamino)cyclopentyl](phenyl)methyl]-2,6-dimethylbenzamide
Isocarbacyclin
(3S,8R,9S,10R,13S,14S)-10,13-Dimethyl-17-pyrimidin-5-yl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol
N-Phenyl-N-[1-[(2S)-1-phenylpropan-2-yl]piperidin-4-yl]propanamide
5-Heptenoic acid, 7-((1S,2R,3S,4R)-3-((1E,3R)-3-hydroxy-1-octen-1-yl)-7-oxabicyclo(2.2.1)hept-2-yl)-, (5Z)-
ent-14S,15-Dihydroxy-1(10),13(16)-halimadien-18-oic acid methyl ester
Methyl 2beta,3beta-dihydroxy-8(17),13E-labdadien-15-oate
3,5-Dihydroxy-4-(3,7-dimethylocta-2,7-dienyl)bibenzyl
carbacyclin
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors
Mefentanyl
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics
(3R,5R,6R,8S,9R,10R,13R,14R,17S,20R)-3,5-cyclopregnane-6,8,14,20-tetraol
3-Ac-(3beta,5alpha,6alpha,17beta)-Androstane-3,6,17-triol
methyl-2-oxo-3beta,4beta-epoxy-neo-clerodan-15-oate|methyl-3,4-beta-epoxy-kolavan-2-on-15-oate
methyl-(13R,14R)-epoxy-15-hydroxy-1(10)-ent-halimen-18-oate
3beta,8beta,14beta-Trihydroxy-20-oxo-5alpha,17alpha-pregnan
3alpha,16,18-trihydroxy-14beta-methoxy-ent-abieta-7,15(17)-diene|parvifoline M
16-hydroxy-17-methoxy-ent-labda-7,13(14)-diene-15-oic acid
methyl-7alpha-hydroxyl-7,8-dihydro-8(17)-dehydrogrindeloate
3alpha-Hydroxy-15-oxo-seco-beyeran-16-saeure-methylester
hydroperoxyclerodane|Methyl 3beta-hydroperoxy-4,18-dehydro-3,4-dihydrokolavenoate
(3alpha,5beta,17alphaOH,20S)-3,17,20-Trihydroxypregnan-1-one
3alpha,16,18-trihydroxy-7beta-methoxy-ent-abieta-8(14),15(17)-diene|parvifoline N
17-hydroxygrindelic acid methyl ester|methyl 17-oxygrindelate
(3alpha,5beta,7beta,15beta)-3,7,15-Trihydroxypregnan-20-one
19-Carboxylic acid,Me ester-(ent-16betaOH)-16,17,19-Kauranetriol
ceriopsin B|methyl 16(R)-16,17-dihydroxybeyeran-18-oate
10(S),11(S),12(S)-hepoxilin B3 methyl ester|erythro hepoxilin B3 methyl ester|Methyl (10S,11R,12S)-10-hydroxy-11,12,-epoxyeicosa-5(Z),8(Z),14(Z)-trienoate
19-Hydroxy-15-oxo-seco-beyeran-16-saeure-methylester
8,9-diacetoxyheptadeca-1,11,14-triene|Di-Ac-1,11,14-Heptadecatriene-8,9-diol
(2R)-2-[(3aR,7aR)-3-Methoxy-5-[(1S)-1,3,3-trimethylcyclohexyl]-1,3,3a,6,7,7a-hexahydroisobenzofuran-4-yl]propanoic acid
3beta,12beta,14beta,20beta-Tetrahydroxy-pregnen-5-en, Boucerin
18,19-epoxy-18alpha-methoxy-ent-clerod-3-en-15-oic acid
3beta,20alpha-dihydroxy-5alpha-pregnan-21-oic acid
3-Ac-(3beta,5alpha,16alpha,17alpha)-Androstane-3,16,17-triol
(8R,12R,15S)-11-deoxyprostaglandin E2 methyl ester|11-Desoxy-PGE(2)-methylester|methyl-(5Z,13E)-(8R,12R,15S)-15-hydroxy-9-oxoprosta-5,13-dienoate
methyl 13(S*)-acetoxy-9(Z),11(E),15(Z)-octadecatrienoate
ent-lab-8(17),14-dien-13,16-diol-18-oic acid methyl ester
15,16-epoxy-15alpha-methoxy-ent-clerod-3-en-18-oic acid
3alpha,17beta-dihydroxy-17alpha-methyl-5alpha-androstane-2beta-carboxylic acid
6,18-dihydroxy-ent-labda-7,13E-dien-15-oic acid methyl ester
17-Ac-(3beta,5alpha,6alpha,17beta)-Androstane-3,6,17-triol
methyl (1R,4S,5S,9S,1R)-1-(1,5-dimethyl-4-oxohexyl)-9-hydroxy-4-methyl-spiro<4.5>dec-7-ene-8-carboxylate|methyl (1R,4S,5S,9S,1R)-1-(1,5-dimethyl-4-oxohexyl)-9-hydroxy-4-methyl-spiro[4.5]dec-7-ene-8-carboxylate
(betaxi,1S,2R,4aR,7S,8aR)-7-formyloxy-1,2,3,4,4a,7,8,8a-octahydro-beta,1,2,4a,5-pentamethylnaphthalene-1-pentanoic acid|2beta-(formyloxy)clerod-3-en-15-oic acid
3beta,4alpha,20R-trihydroxy-5alpha-pregn-16-one|toonasterone A
(4alpha,16alpha)-17-(acetyloxy)-19-nor-ent-kaurane-4,16-diol|rel-(2R,4aR,4bS,8R,8aS,10aS,12R)-12-[(acetyloxy)methyl]dodecahydro-4b,8-dimehyl-1H-2,10a-ethanophenanthrene-8,12-diol
12R-12,13-dihydroxylabda-8(20),14-diene-19-oic acid methyl ester
(12S,13E)-12-hydroxy-15-methoxylabda-8(17),13-dien-18-oic acid|(1R*,4aR*,5S*,8aR*)-5-[(2S,3E)-decahydro-2-hydroxy-5-methoxy-3-methylpent-3-en-1-yl]-1,4a-dimethyl-6-methylidenenaphthalene-1-carboxylic acid
Me ester-15-Hydroperoxy-5,8,11,13-eicosatetraenoic
(1xi,3xi,5xi,20xi)-1,3,20-Trihydroxypregnan-11-one
1,19-dihydroxy-6,7-epoxy-12-oxo-smallantha-2Z,10E,14(21)-triene
3-Me ether-3,4-Dihydroxy-13-cleroden-15,16-olide|3alpha-metoxy-4beta-hydroxy-5beta,10beta-cis-17alpha,20alpha-cleroda-13(14)-en-15,16-olide
methyl (13E)-6alpha,18-dihydroxycleroda-3,13-dien-15-oate
methyl-(14S)-14,15-dihydroxylabda-8(17),13(16)-dien-19-oate
(16alpha)-16,17-dihydroxy-ent-atisan-19-oic acid methyl ester|methyl 16beta,17-dihydroxy-ent-atisan-19-oate|methyl 17-hydroxy-16beta-hydroxy-ent-atisan-19-oate
1,19-dihydroxy-6,7-epoxy-12-oxo-smallantha-2Z,10E,13E-triene
2-(3,7-dimethylocta-2,6-dienyl)-5-(2-phenylethyl)benzene-1,3-diol
12beta,17-Dihydroxy-16alpha-(-)-kauran-19-saeure-methylester
(2S,5R,8R,9S,10R)-2-hydroperoxy-ent-clerod-3,13-dien-15-oic acid methyl ester
2,4-bis(3-methylbut-2-enyl)-5-(2-phenylethyl)benzene-1,3-diol
(5R)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one
10-gingerol
10-Gingerol is a major pungent constituent in the ginger oleoresin from fresh rhizome, with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM[1][2]. 10-Gingerol is a major pungent constituent in the ginger oleoresin from fresh rhizome, with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM[1][2].
C21H34O4_1-Naphthalenepentanoic acid, decahydro-5-(methoxycarbonyl)-beta,5,8a-trimethyl-2-methylene
4-acetyloxy-8-(3-oxo-2-pent-2-enylcyclopenten-1-yl)octanoic acid
(5R)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one
4-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-1-hydroxyethyl]-2H-furan-5-one
6,10a-dihydroxy-4-(hydroxymethyl)-4,7,11b-trimethyl-1,2,3,4a,5,6,6a,7,11,11a-decahydronaphtho[2,1-f][1]benzofuran-9-one
(3E,4R)-3-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one
5-(4-carboxy-3-methylbutyl)-5,6,8a-trimethyl-3-oxo-4a,6,7,8-tetrahydro-4H-naphthalene-1-carboxylic acid
2,4-bis(3-methylbut-2-enyl)-5-(2-phenylethyl)benzene-1,3-diol
5-(5-methoxycarbonyl-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl)-3-methylpentanoic acid
6,8-dihydroxy-3-(10-hydroxyundecyl)-3,4-dihydroisochromen-1-one
5-(4-carboxy-3-methylbutyl)-5,6,8a-trimethyl-3-oxo-4a,6,7,8-tetrahydro-4H-naphthalene-1-carboxylic acid [IIN-based: Match]
(5R)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one [IIN-based on: CCMSLIB00000848859]
6,8-dihydroxy-3-(10-hydroxyundecyl)-3,4-dihydroisochromen-1-one [IIN-based on: CCMSLIB00000846799]
5-(4-carboxy-3-methylbutyl)-5,6,8a-trimethyl-3-oxo-4a,6,7,8-tetrahydro-4H-naphthalene-1-carboxylic acid [IIN-based on: CCMSLIB00000847901]
5-(4-carboxy-3-methylbutyl)-5,6,8a-trimethyl-3-oxo-4a,6,7,8-tetrahydro-4H-naphthalene-1-carboxylic acid [IIN-based on: CCMSLIB00000847900]
(5R)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one [IIN-based: Match]
6,8-dihydroxy-3-(10-hydroxyundecyl)-3,4-dihydroisochromen-1-one [IIN-based: Match]
(5R)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one_34.2\\%
(5R)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one_major
(3E,4R)-3-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one_major
6,8-dihydroxy-3-(10-hydroxyundecyl)-3,4-dihydroisochromen-1-one_major
(5R)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one_36.6\\%
2,4-bis(3-methylbut-2-enyl)-5-(2-phenylethyl)benzene-1,3-diol_major
8-(3-((1-Ethoxy-2-methyl-1-oxopropan-2-yl)oxy)phenyl)octanoic acid
5,6,15-trihydroxy-7,9,13-Eicosatrien-11-ynoic acid
Prostaglandin K2
Allotetrahydrocorticosterone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Resolvin E1
A resolvin that is (6Z,8E,10E,14Z,16E)-icosa-6,8,10,14,16-pentaenoic acid which is substituted at positions 5, 12 and 18 by hydroxy groups (the 5S,12R,18R stereoisomer).
(ent-6alpha,7alpha,12alpha)-6,7,12-Trihydroxy-16-kauren-19-oic acid
Oryzalic acid A
Oryzalic acid B
5-[5-(Methoxycarbonyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]-3-methylpentanoic acid
6,8-Dihydroxy-3-(10-hydroxyundecyl)-3,4-dihydro-1H-isochromen-1-one
(E)-4-acetoxy-8-(3-oxo-2-(pent-2-en-1-yl)cyclopent-1-en-1-yl)octanoic acid
6,10a-Dihydroxy-4-(hydroxymethyl)-4,7,11b-trimethyl-2,3,4,4a,5,6,6a,7,10a,11,11a,11b-dodecahydrophenanthro[3,2-b]furan-9(1H)-one
5-(4-Carboxy-3-methylbutyl)-5,6,8a-trimethyl-3-oxo-3,4,4a,5,6,7,8,8a-octahydro-1-naphthalenecarboxylic acid
ST 21:1;O4
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Pregnanetriolone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
3-BETA,11-BETA,21-TRIHYDROXY-5-ALPHA-PREGNAN-20-ONE
9-O-methanoprostaglandin I
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents D050299 - Fibrin Modulating Agents D002317 - Cardiovascular Agents
15-Hydroxy-11alpha,9alpha-(epoxymethano)prosta-5,13-dienoic acid
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents D009676 - Noxae > D016877 - Oxidants > D010545 - Peroxides
N-[[1-(Dimethylamino)cyclopentyl](phenyl)methyl]-2,6-dimethyl benzamide
3,4-Dihydro-6,8-dihydroxy-3-(10-hydroxyundecyl)isocoumarin
(2alpha,5alpha,17beta)-17-(Acetyloxy)-2-fluoro-androstan-3-one
5alpha-Androstane-2beta-fluoro-17beta-ol-3-one acetate
(5E,13E)-11-Hydroxy-9,15-dioxoprosta-5,13-dien-1-oic acid
Tetrahydrocorticosterone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones Tetrahydrocorticosterone is one of the major urinary metabolites from corticosterone. Premenopausal patients with early breast cancer excrete subnormal amounts of tetrahydrocorticosterone as compared with the normal subjects of corresponding ages. (PMID 1133844) [HMDB]
3,5-Dihydroxy-4-(3,7-dimethyl-2,6-octadienyl) bibenzyl
(Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-methylidenecyclopentyl]hept-5-enoic acid
(5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoic acid
A polyunsaturated fatty acid that is (6E,8Z,11Z,14Z,16E)-icosapentaenoic acid substituted at positions 5 and 18 by hydroperoxy and hydroxy groups respectively (the 5S, 18S-stereoisomer).
8-iso-15-keto-PGE2
8-iso-15-keto-PGE2 is an isoprostane. Isoprostanes are arachidonic acid metabolites produced by peroxidative attack of membrane lipids. These accumulate to substantial levels in many clinical conditions characterized in part by accumulation of free radicals and reactive oxygen species, including asthma, hypertension and ischemia reperfusion injury. For this reason, they are frequently used as markers of oxidative stress; however, many are now finding that these molecules are not inert, but in fact evoke powerful biological responses in an increasing array of cell types. In many cases, these biological effects can account in part for the various features and manifestations of those clinical conditions. Thus, it may be possible that the isoprostanes are playing somewhat of a causal role in those disease states (PMID: 14504139). Dinoprostone is a naturally occurring prostaglandin E2 (PGE2) and the most common and most biologically active of the mammalian prostaglandins. It has important effects in labour and also stimulates osteoblasts to release factors which stimulate bone resorption by osteoclasts (a type of bone cell that removes bone tissue by removing the bones mineralized matrix). PGE2 has been shown to increase vasodilation and cAMP production, to enhance the effects of bradykinin and histamine, to induce uterine contractions and to activate platelet aggregation. PGE2 is also responsible for maintaining the open passageway of the fetal ductus arteriosus; decreasing T-cell proliferation and lymphocyte migration and activating the secretion of IL-1alpha and IL-2. PGE2 exhibits both pro- and anti-inflammatory effects, particularly on dendritic cells (DC). Depending on the nature of maturation signals, PGE2 has different and sometimes opposite effects on DC biology. PGE2 exerts an inhibitory action, reducing the maturation of DC and their ability to present antigen. PGE2 has also been shown to stimulate DC and promote IL-12 production when given in combination with TNF-alpha. PGE2 is an environmentally bioactive substance. Its action is prolonged and sustained by other factors especially IL-10. It modulates the activities of professional DC by acting on their differentiation, maturation and their ability to secrete cytokines. PGE2 is a potent inducer of IL-10 in bone marrow-derived DC (BM-DC), and PGE2-induced IL-10 is a key regulator of the BM-DC pro-inflammatory phenotype (PMID: 16978535). Prostaglandins are eicosanoids. The eicosanoids consist of the prostaglandins (PGs), thromboxanes (TXs), leukotrienes (LTs), and lipoxins (LXs). The PGs and TXs are collectively identified as prostanoids. Prostaglandins were originally shown to be synthesized in the prostate gland, thromboxanes from platelets (thrombocytes), and leukotrienes from leukocytes, hence the derivation of their names. All mammalian cells except erythrocytes synthesize eicosanoids. These molecules are extremely potent, able to cause profound physiological effects at very dilute concentrations. All eicosanoids function locally at the site of synthesis, through receptor-mediated G-protein linked signalling pathways. 8-iso-15-keto-PGE2 is an isoprostane. Isoprostanes are arachidonic acid metabolites produced by peroxidative attack of membrane lipids. These accumulate to substantial levels in many clinical conditions characterized in part by accumulation of free radicals and reactive oxygen species, including asthma, hypertension and ischemia reperfusion injury. For this reason, they are frequently used as markers of oxidative stress; however, many are now finding that these molecules are not inert, but in fact evoke powerful biological responses in an increasing array of cell types. In many cases, these biological effects can account in part for the various features and manifestations of those clinical conditions. Thus, it may be possible that the isoprostanes are playing somewhat of a causal role in those disease states. (PMID: 14504139)
(3E)-3-[2-[(8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one
(1E,3R,4S,10R,11S)-14-(methoxymethyl)-3,10-dimethyl-6-propan-2-yltricyclo[9.3.0.03,7]tetradeca-1,6-diene-4,9,14-triol
(5S)-hydroperoxy-18-hydroxy-EPE
An icosanoid that is (6E,8Z,11Z,14Z,16E)-icosa-6,8,11,14,16-pentaenoic acid substituted at positions 5S and 18 by hydroperoxy and hydroxy groups respectively.
2(3H)-Furanone, 3-[2-[decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-
(E)-7-[3-[(1E,5E)-3-hydroxyocta-1,5-dienyl]-2,6-dioxabicyclo[3.1.1]heptan-4-yl]hept-5-enoic acid
(Z)-7-[(1R,4S,5R,6S)-5-[(E,3R)-3-Hydroxyoct-1-enyl]-2-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid
(5Z)-7-[(1alpha,4alpha)-3beta-[(1E,3S)-3-Hydroxy-1-octenyl]-7-oxabicyclo[2.2.1]heptane-2alpha-yl]-5-heptenoic acid
(5S)-Hydroperoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate
(5E)-5-[(3Ar,4S,5S,6aR)-5-hydroxy-4-[(E,3R)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid
(Z)-7-[(1R,3R)-3-Hydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopentyl]hept-5-enoic acid
(5Z)-5-[5-hydroxy-4-[(1E,5E)-3-hydroxyocta-1,5-dienyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid
(2E,6E)-8-{[(2E,6E)-8-hydroxy-2,6-dimethylocta-2,6-dienoyl]oxy}-2,6-dimethylocta-2,6-dienoic acid
A natural product found in Anarrhinum orientale.
(5Z)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors
rel-(-)-(1S,4S,7S,10R)-1,4,7-trihydroxycembra-2E,8-(19),11Z-trien-20,10-olide
A cembrane diterpenoid that is cembra-2E,8-(19),11Z-trien-20,10-olide substituted by hydroxy groups at positions 1, 4 and 7. It has been isolated from the leaves of Croton gratissimus.
rel-(+)-(1S,4S,7R,10R)-1,4,7-trihydroxycembra-2E,8-(19),11Z-trien-20,10-olide
A cembrane diterpenoid that is cembra-2E,8-(19),11Z-trien-20,10-olide substituted by hydroxy groups at positions 1, 4 and 7. It has been isolated from the leaves of Croton gratissimus.
(7E,11E)-14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-1-oxacyclotetradeca-7,11-diene-2,6,10-trione
7-(1-Azepanyl)-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine
1-[1-(1-Adamantyl)butyl]-3-(2-oxolanylmethyl)thiourea
C20H34N2OS (350.23917140000003)
(E)-7-[(1R,4S,5S,6R)-6-[(3S)-3-hydroxyoct-1-enyl]-2-oxabicyclo[2.2.1]heptan-5-yl]hept-5-enoic acid
N-tert-butyl-N-(2,6-diisopropyl-4-phenoxyphenyl)methanediimine
rel-(+)-(1S,4R,8S,10R)-1,4,8-trihydroxycembra-2E,6E,11Z-trien-20,10-olide
A cembrane diterpenoid that is cembra-2E,8-(19),11Z-trien-20,10-olide substituted by hydroxy groups at positions 1, 4 and 8. It has been isolated from the leaves of Croton gratissimus.
(2S)-hydroxy[(9Z,12Z,15Z)-octadeca-9,12,15-trienoylamino]acetate
3alpha,20alpha,21-Trihydroxy-5beta-pregnane-11-one
2-(1,5-Diphenylpentan-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
C23H31BO2 (350.24169759999995)
9-Fluoro-11beta,17beta-dihydroxy-2,17-dimethylandrost-4-en-3-one
(5S,6Z,8E,10E,14Z)-5,20-dihydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid
(7E,9E,11Z,13E,15R,17Z)-5,6,15-trihydroxyicosa-7,9,11,13,17-pentaenoic acid
(6Z,8E,10E,14Z,16E,18R)-5,12,18-trihydroxyicosa-6,8,10,14,16-pentaenoic acid
(3E)-4-hydroxy-3-[2-[6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]oxolan-2-one
1-[(10S,13S,16R,17S)-3,16,17-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone
[1-[(4Z,7Z,10Z,13Z)-hexadeca-4,7,10,13-tetraenoxy]-3-hydroxypropan-2-yl] acetate
3,3,5,5-Tetra-methyl-4,4-dicyclopropyl-methyloxy-biphenyl
1-Methyl-4-(11-methoxycarbonyl-5,9-dimethyl-1-oxoundeca-4,8-dienyl)-piperadine
methyl (4Z,8E)-4,8-dimethyl-12-oxo-12-[4-(trideuteriomethyl)piperazin-1-yl]dodeca-4,8-dienoate
1-O-(1-Oxo-6,9,12,15-octadecatetraenyl)-L-glycerol
1,1,1-Trideuteriomethyl-4-(5,9-dimethyl-11-methoxycarbonyl-1-oxoundeca-4,8-dienyl)-piperadine
[(2S)-2,3-dihydroxypropyl] (9E,11E,13E,15E)-octadeca-9,11,13,15-tetraenoate
Gingerol
(10)-Gingerol is a beta-hydroxy ketone, a member of phenols and a monomethoxybenzene. (10)-Gingerol is a natural product found in Zingiber officinale with data available. See also: Ginger (part of). 10-Gingerol is a major pungent constituent in the ginger oleoresin from fresh rhizome, with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM[1][2]. 10-Gingerol is a major pungent constituent in the ginger oleoresin from fresh rhizome, with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM[1][2].
15-dehydro-prostaglandin D2
The 15-dehydro derivative of prostaglandin D2.
5S-hydroperoxy-18R-hydroxy-6E,8Z,11Z,14Z,16E-eicosapentaenoic acid
3alpha,11beta,17alpha-Trihydroxy-5beta-pregnan-20-one
Tetrahydrodeoxycortisol
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Prostaglandin D3
A member of the class of prostaglandins D that is prosta-5,13,17-trien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5Z,13E,15S,17Z-stereoisomer).
(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxy-20-oxoicosa-6,8,10,14-tetraenoic acid
5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one
Prostaglandin H3
A member of the class of prostaglandins H that is 9,11-epidioxyprosta-5,13,17-trienoic acid carrying an additional hydroxy substituent at the 15S-position.
15-oxolipoxin A4
A C20 hydroxy fatty acid having (5S)- and (6R)- -hydroxy groups as well as a 15-oxo group and (7E)- (9E)-, (11Z)- and (13E)-double bonds.
5(S)-hydroperoxy-18(R)-hydroxy-(6E,8Z,11Z,14Z,16E)-icosapentaenoic acid
A polyunsaturated fatty acid that is (6E,8Z,11Z,14Z,16E)-icosapentaenoic acid substituted at positions 5 and 18 by hydroperoxy and hydroxy groups respectively (the 5S, 18R-stereoisomer).
20-Oxoleukotriene b4
A leukotriene that is leukotriene B4 bearing an additional oxo substituent at position 20.
(18S)-resolvin E1
A resolvin that is (6Z,8E,10E,14Z,16E)-icosa-6,8,10,14,16-pentaenoic acid which is substituted at positions 5, 12 and 18 by hydroxy groups (the 5S,12R,18S stereoisomer).
DG(18:4)
Provides by LipidSearch Vendor. © Copyright 2006-2024 Thermo Fisher Scientific Inc. All rights reserved
DG(17:4)
Provides by LipidSearch Vendor. © Copyright 2006-2024 Thermo Fisher Scientific Inc. All rights reserved
methyl (2s,4as,4br,8r,8as,10as)-10a-formyl-8-(hydroxymethyl)-2,4b,8-trimethyl-decahydrophenanthrene-2-carboxylate
methyl 2-{4-hydroxy-2,5,5,5',8a-pentamethyl-4a,6,7,8-tetrahydro-4h-spiro[naphthalene-1,2'-oxolan]-5'-yl}acetate
methyl 2-[(1s,4as,5's,8as)-2-(hydroxymethyl)-5,5,5',8a-tetramethyl-4a,6,7,8-tetrahydro-4h-spiro[naphthalene-1,2'-oxolan]-5'-yl]acetate
(3s)-5-[(1s,4ar,5r,8ar)-5-(methoxycarbonyl)-5,8a-dimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]-3-methylpentanoic acid
methyl 10a-formyl-7-hydroxy-2,4b,8,8-tetramethyl-decahydrophenanthrene-2-carboxylate
methyl (1s,4s,5r,9s,10r,13r,14s)-14-hydroxy-14-(hydroxymethyl)-5,9-dimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecane-5-carboxylate
(1e,3r,4s,9s,10r,11s,14r)-6-isopropyl-14-(methoxymethyl)-3,10-dimethyltricyclo[9.3.0.0³,⁷]tetradeca-1,6-diene-4,9,14-triol
2-[3-methoxy-5-(1,3,3-trimethylcyclohexyl)-1,3,3a,6,7,7a-hexahydro-2-benzofuran-4-yl]propanoic acid
methyl 12-hydroxy-14-(hydroxymethyl)-5,9-dimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecane-5-carboxylate
methyl (2e)-5-[(1s,4as,6r,7s,8ar)-6,7-dihydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]-3-methylpent-2-enoate
(1s,4s,5r,9s,10s,13r,14s)-5-hydroxy-14-(hydroxymethyl)-5,9-dimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-14-yl acetate
methyl 5-(3,6-dihydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)-3-methylpent-2-enoate
methyl 2-{3-hydroxy-2,5,5,5',8a-pentamethyl-4a,6,7,8-tetrahydro-4h-spiro[naphthalene-1,2'-oxolan]-5'-yl}acetate
methyl (2s,4as,4br,7r,8as,10as)-10a-formyl-7-hydroxy-2,4b,8,8-tetramethyl-decahydrophenanthrene-2-carboxylate
(5s)-3-[(3e)-6-[(1s,2s)-2-hydroxy-2,6,6-trimethylcyclohexyl]-4-methylhex-3-en-1-yl]-5-methoxy-5h-furan-2-one
(1s,4s,5r,9s,10r,13r,14s)-5-hydroxy-14-(hydroxymethyl)-5,9-dimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecan-14-yl acetate
(3r)-5-[(1s,2r,4ar,7s,8ar)-7-(formyloxy)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]-3-methylpentanoic acid
(1s,3as,3br,5ar,6s,7s,9ar,9bs,11as)-6,7-dihydroxy-1-[(1r)-1-hydroxyethyl]-9a,11a-dimethyl-tetradecahydrocyclopenta[a]phenanthren-2-one
(3r,4r,9s,10r,11s,14r)-6-isopropyl-14-(methoxymethyl)-3,10-dimethyltricyclo[9.3.0.0³,⁷]tetradeca-1,6-diene-4,9,14-triol
1-{5-[(2e)-3,7-dimethylocta-2,6-dien-1-yl]-1,3,5-trihydroxycyclohex-2-en-1-yl}-3-methylbutan-1-one
methyl 10-hydroxy-10-[3-(oct-2-en-1-yl)oxiran-2-yl]deca-5,8-dienoate
5-[5-(methoxycarbonyl)-5,8a-dimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]-3-methylpentanoic acid
5-[7-(formyloxy)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]-3-methylpentanoic acid
methyl 5-(3-ethenyl-3,4-dihydroxybutyl)-1,4a-dimethyl-6-methylidene-hexahydro-2h-naphthalene-1-carboxylate
methyl (1s,4ar,5s,8ar)-5-[(4s)-4,5-dihydroxy-3-methylidenepentyl]-1,4a-dimethyl-6-methylidene-hexahydro-2h-naphthalene-1-carboxylate
14-[hydroxy(methoxy)methyl]-5,9-dimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecane-5-carboxylic acid
16,17-dihydroxy-16beta-(i)-kauran-19-oic acid
{"Ingredient_id": "HBIN001746","Ingredient_name": "16,17-dihydroxy-16beta-(i)-kauran-19-oic acid","Alias": "NA","Ingredient_formula": "C21H34O4","Ingredient_Smile": "CC12CCCC(C1CCC34C2CCC(C3)C(C4)(CO)O)(C)C(=O)OC","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "30918","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
annosquamosin d
{"Ingredient_id": "HBIN016235","Ingredient_name": "annosquamosin d","Alias": "NA","Ingredient_formula": "C21H34O4","Ingredient_Smile": "CC(=O)OC1(CC23CCC4C(C2CCC1C3)(CCCC4(C)O)C)CO","Ingredient_weight": "350.5 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "1328","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "11759899","DrugBank_id": "NA"}