Exact Mass: 350.0134786

Exact Mass Matches: 350.0134786

Found 36 metabolites which its exact mass value is equals to given mass value 350.0134786, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Apigenin 7-sulfate

[5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl]oxidanesulfonic acid

C15H10O8S (350.00963800000005)

Apigenin 7-sulfate is isolated from Bixa orellana (annatto) Apigenin is a flavone that is the aglycone of several glycosides. It is a yellow crystalline solid that has been used to dye wool. Apigenin is a plant-derived flavonoid that has significant promise as a skin cancer chemopreventive agent. Apigenin inhibits the expression of involucrin (hINV), a marker of keratinocyte differentiation, is increased by differentiating agents via a protein kinase Cdelta (PKCdelta), Ras, MEKK1, MEK3 cascade that increases AP1 factor level and AP1 factor binding to DNA elements in the hINV promoter. Apigenin suppresses the 12-O-tetradeconylphorbol-13-acetate-dependent increase in AP1 factor expression and binding to the hINV promoter and the increase in hINV promoter activity. Apigenin also inhibits the increase in promoter activity observed following overexpression of PKCdelta, constitutively active Ras, or MEKK1. The suppression of PKCdelta activity is associated with reduced phosphorylation of PKCdelta-Y311. Activation of hINV promoter activity by the green tea polyphenol, (-)-epigellocathecin-3-gallate, is also inhibited by apigenin, suggesting that the two chemopreventive agents can produce opposing actions in keratinocytes. (PMID: 16982614); Apigenin, a flavone abundantly found in fruits and vegetables, exhibits antiproliferative, anti-inflammatory, and antimetastatic activities through poorly defined mechanisms. This flavonoid provides selective activity to promote caspase-dependent-apoptosis of leukemia cells and uncover an essential role of PKCdelta during the induction of apoptosis by apigenin. (PMID: 16844095); Apigenin markedly induces the expression of death receptor 5 (DR5) and synergistically acts with exogenous soluble recombinant human tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to induce apoptosis in malignant tumor cells. On the other hand, apigenin-mediated induction of DR5 expression is not observed in normal human peripheral blood mononuclear cells. Moreover, apigenin does not sensitize normal human peripheral blood mononuclear cells to TRAIL-induced apoptosis. (PMID: 16648565); Apigenin is a potent inhibitor of CYP2C9, an enzyme responsible for the metabolism of many pharmaceutical drugs in the body. Isolated from Bixa orellana (annatto)

Genistein 7-sulfate

[5-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl]oxidanesulfonic acid

C15H10O8S (350.00963800000005)

Chloromonilicin

C16H11ClO7 (350.0193286)

An organic heterotricyclic compound that is 5-chloro-10-hydroxy-8-methyl-1H-oxepino[4,3-b]chromene-3,11-dione which is substituted at positions 1, 5, 8, and 10 by methoxycarbonyl, chlorine, methyl, and hydroxy groups, respectively (the 1S enantiomer). Found in Monilia fructicola and in the mycoherbicide Alternaria sonchi.

Exact Mass: 350.0134786

Exact Mass Matches: 350.0134786

Apigenin 7-sulfate

Genistein 7-sulfate

Chloromonilicin

Galangin-8-sulfonate

Apigenin 7-sulfate

3-[(2-{[(3,5-Dichloro-2-hydroxyphenyl)methylene]amino}phenyl)sulfanyl]propanenitrile

SCHEMBL299473

Genistein 7-O-phosphate

ammonium heptafluorotantalate(v)

1,7-dichlorooctamethyltetrasiloxane

TERT-BUTYL 5-METHOXY-3,4-DIHYDRO-1,7-NAPHTHYRIDINE-1(2H)-CARBOXYLATE

2-(2,4-DICHLORO-5-FLUORO-BENZOYL)-MALONIC ACID DIETHYL ESTER

dimethyl perfluoro-3,6-dioxaoctane-1,8-dioate

6-(2,6-Dichlorophenyl)-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-imine

tert-Butyl 5-iodo-4-methoxypyridin-2-ylcarbamate

[4-[3-(3,4-DICHLOROPHENYL)-1-OXO-2-PROPENYL]PHENOXY]-ACETIC ACID

[4-[3-(3,4-dichlorophenyl)-3-oxo-1-propenyl]phenoxy-acetic acid

1,3,4-Oxadiazole,2-(3-bromophenyl)-5-(2-naphthalenyl)-

methyl 5-bromo-2-methoxy-4-phenylmethoxybenzoate

2-(1-AMINOETHYL)-N-(5-CHLORO-4-(TRIFLUOROMETHYL)PYRIDIN-2-YL)THIAZOLE-5-CARBOXAMIDE

3-Chloro-5-(4-chloro-phenyl)-4-(2,6-difluoro-phenyl)-6-methyl-pyridazine

2-(4-BROMOPHENYL)-5-(1-NAPHTHYL)-1,3,4-OXADIAZOLE

5-[Bis-2(chloro-ethyl)-amino]-2,4-dintro-benzamide

(+)-Chloromonilicin

Bis(2,4-dinitrophenyl) ether

Genistein 4-sulfate

1-(3,5-dichlorophenyl)-3-(N-hydroxyanilino)pyrrolidine-2,5-dione

[2-Hydroxy-5-(7-hydroxy-4-oxochromen-2-yl)phenyl] hydrogen sulate

[3-(6,7-Dihydroxy-4-oxochromen-2-yl)phenyl] hydrogen sulate

[3-(3,5-Dihydroxy-7-oxochromen-2-yl)phenyl] hydrogen sulfate

2-Iodo-1-phenoxy-3-trimethylsiloxypropane

Genistein 7-sulfate

methyl 5-chloro-4,8-dihydroxy-6-(hydroxymethyl)-9-oxoxanthene-3-carboxylate

3,5,7-trihydroxy-4-oxo-2-phenylchromene-8-sulfonic acid

methyl 5-chloro-10-hydroxy-8-methyl-3,11-dioxo-1h-oxepino[4,3-b]chromene-1-carboxylate

(4,5-dihydroxy-7-methyl-9,10-dioxoanthracen-2-yl)oxidanesulfonic acid