Exact Mass: 319.1045

Exact Mass Matches: 319.1045

Found 2 metabolites which its exact mass value is equals to given mass value 319.1045, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

   

Ro 67-7476

Ro 67-7476

C17H18FNO2S (319.1042)


Ro 67-7476 is a potent positive allosteric modulator of mGluR1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC50 of 60.1 nM[1][2]. Ro 67-7476 is a potent P-ERK1/2 agonist?and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate (EC50=163.3 nM)[3].